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  • 1995-1999  (7)
  • 1995  (7)
  • 1
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This presentation reviews recent progress in knowledge of (i) molecular biology and immunology of allergens and (ii) the methods for the modulation of allergen-specific immune response, with special emphasis on our grass pollen allergens, particularly Pao p IX AL, used as a model. The last few years have seen tremendous progress in molecular characterization of allergens, leading to synthesis of a number of recombinant allergens. Furthermore, studies of the structure-activity relationship of allergens have led to the delineation of the epitopes of these allergens and of widespread cross-reactivities among diverse allergens. In view of the requirement for extensive pre-clinical studies, the application of the recombinant allergens and epitopes in the clinical realm has just begun. Studies in murine systems suggest that these allergens and/or their epitopic peptides downregulate allergen-specific immune responses de novo. The potential and drawbacks of the recombinant allergens and peptides for improving the existing immunotherapeutic approaches and for developing new approaches to specific immunotherapy are discussed.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Astrophysics and space science 231 (1995), S. 89-92 
    ISSN: 1572-946X
    Keywords: Gamma-ray:Bursts ; ISM:Individual (G10.0-0.3) ; Supernova remnants
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We present CO(1-0) observations toward the soft gamma-ray repeater SGR 1806-20. We discuss the implications on the distance to the X-ray counterpart: AX 1805.7-2025. We also present an upper limit at λ = 1.3 mm for the thermal emission from dust and high resolution IRAS maps of the region. SGR 1806-20 is very likely associated with the H II complex W31. The G10.0-0.3 supernova remnant (SNR) could be expanding in the very low density region produced by the wind of the bright O9-B2 star recently detected.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 44 (1995), S. 507-513 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract  Ruminal cellulolytic bacteria (Fibrobacter succinogenes S85 or Ruminococcus flavefaciens FD-1) were combined with the non-ruminal bacterium Clostridium kluyveri and grown together on cellulose and ethanol. Succinate and acetate produced by the cellulolytic organisms were converted to butyrate and caproate only when the culture medium was supplemented with ethanol. Ethanol (244 mM) and butyrate (30 mM at pH 6.8) did not inhibit cellulose digestion or product formation by S85 or FD-1; however caproate (30 mM at pH 6.8) was moderately inhibitory to FD-1. Succinate consumption and caproate production were sensitive to culture pH, with more caproic acid being produced when the culture was controlled at a pH near neutrality. In a representative experiment under conditions of controlled pH (at 6.8) 6.0 g cellulose l-1 and 4.4 g ethanol l-1 were converted to 2.6 g butyrate l-1 and 4.6 g caproate l-1. The results suggest that bacteria that efficiently produce low levels of ethanol and acetate or succinate from cellulose should be useful in cocultures for the production of caproic acid, a potentially useful industrial chemical and bio-fuel precursor.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Applied microbiology and biotechnology 44 (1995), S. 507-513 
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Ruminal cellulolytic bacteria (Fibrobacter succinogenes S85 or Ruminococcus flavefaciens FD-1) were combined with the non-ruminal bacterium Clostridium kluyveri and grown together on cellulose and ethanol. Succinate and acetate produced by the cellulolytic organisms were converted to butyrate and caproate only when the culture medium was supplemented with ethanol. Ethanol (244 mM) and butyrate (30 mM at pH 6.8) did not inhibit cellulose digestion or product formation by S85 or FD-1; however caproate (30 mM at pH 6.8) was moderately inhibitory to FD-1. Succinate consumption and caproate production were sensitive to culture pH, with more caproic acid being produced when the culture was controlled at a pH near neutrality. In a representative experiment under conditions of controlled pH (at 6.8) 6.0 g cellulose 1−1 and 4.4 g ethanol 1−1 were converted to 2.6 g butyrate 1−1 and 4.6 g caproate 1−1. The results suggest that bacteria that efficiently produce low levels of ethanol and acetate or succinate from cellulose should be useful in cocultures for the production of caproic acid, a potentially useful industrial chemical and bio-fuel precursor.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Journal of low temperature physics 101 (1995), S. 605-610 
    ISSN: 1573-7357
    Keywords: 72.15. Jf ; 71.20.Hk ; 71.55.Jv
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Advances in the synthesis of organic conducting polymer systems has increased the electrical conductivity of these systems by several orders of magnitude in the last decade. Several practical applications are envisioned for such systems, but a thorough understanding of the conduction mechanisms and identification of the charge carriers is lacking, making design and implementation for bulk synthesis difficult. In order to clarify our understanding of the electrical properties of these systems, the resistivity and magnetoresistivity of various polymers doped near the metal - insulator transition, such as polyaniline protonated by camphor sulfonic acid (PANi-CSA) and polypyrrole doped with PF6 (PPy-PF6), have been studied down to 25 mK in magnetic fields up to 16 T.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Journal of superconductivity 8 (1995), S. 393-396 
    ISSN: 1572-9605
    Keywords: high temperature superconductivity ; pressure effect
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract We have observed a δ-independent linear pressure effect on Tc of HgBa2CuO4+δ under hydrostatic pressures up to 1.7 GPa for δ≤0.30 but a nonlinear effect for δ〉0.30. These results, together with previous doping data, show a possible non-rigidity of the electron bands of the compounds, based on which previous phenomenological models of the pressure effect on Tc are built, and thus suggest only a restricted universality for the inverse parabolic relation between Tc and charge carriers per CuO2-layer. In other words, factors in addition to charge carriers can affect high temperature superconductivity.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Journal of superconductivity 8 (1995), S. 465-466 
    ISSN: 1572-9605
    Keywords: penetration depth ; doping
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology , Physics
    Notes: Abstract The magnetic penetration depth λ(T) of three HgBa2CuO4+δ samples with 0.16 〈 δ ≤ 0.27 has been determined from the reversible magnetization. The obtained λ follows a BCS-like correlation of 1/λ2 ∝ 1−(T/Tc)2 over whole measured temperature range in an underdoped sample with Tc ∼ 90 K, but deviates significantly from similar fits in an overdoped sample with the same Tc and an optimum doped sample, whose 1/λ2 's depends on T nearly linearly below Tc/2. This asymmetry between the underdoped and overdoped samples suggests that the T-dependence of 1/λ2 is affected by doping in a complicated way.
    Type of Medium: Electronic Resource
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