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  • 1995-1999  (5)
  • 1905-1909
  • 1996  (5)
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  • 1995-1999  (5)
  • 1905-1909
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  • 1
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Reliable operation of discharges with negative central magnetic shear has led to significant increases in plasma performance and reactivity in both low confinement, L-mode, and high confinement, H-mode, regimes in the DIII-D tokamak [Plasma Physics and Controlled Nuclear Fusion Research 1986 (International Atomic Energy Agency, Vienna, 1987), Vol. 1, p. 159]. Using neutral beam injection early in the initial current ramp, a large range of negative shear discharges have been produced with durations lasting up to 3.2 s. The total noninductive current (beam plus bootstrap) ranges from 50% to 80% in these discharges. In the region of shear reversal, significant peaking of the toroidal rotation [fφ(0)∼30–60 kHz] and ion temperature [Ti(0)∼15–22 keV] profiles are observed. In high-power discharges with an L-mode edge, peaked density profiles are also observed. Confinement enhancement factors up to H≡τE/τITER-89P∼2.5 with an L-mode edge, and H∼3.3 in an edge localized mode (ELM)-free H mode, are obtained. Transport analysis shows both ion thermal diffusivity and particle diffusivity to be near or below standard neoclassical values in the core. Large pressure peaking in the L mode leads to high disruptivity with βN≡βT/(I/aB)≤2.3, while broader pressure profiles in the H mode gives low disruptivity with βN≤4.2. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The confinement and the stability properties of the DIII-D tokamak [Plasma Physics and Controlled Nuclear Fusion Research 1986 (International Atomic Energy Agency, Vienna, 1987), Vol. 1, p. 159] high-performance discharges are evaluated in terms of rotational and magnetic shear, with an emphasis on the recent experimental results obtained from the negative central magnetic shear (NCS) experiments. In NCS discharges, a core transport barrier is often observed to form inside the NCS region accompanied by a reduction in core fluctuation amplitudes. Increasing negative magnetic shear contributes to the formation of this core transport barrier, but by itself is not sufficient to fully stabilize the toroidal drift mode (trapped-electron-ηi mode) to explain this formation. Comparison of the Doppler shift shear rate to the growth rate of the ηi mode suggests that the large core E×B flow shear can stabilize this mode and broaden the region of reduced core transport. Ideal and resistive stability analysis indicates the performance of NCS discharges with strongly peaked pressure profiles is limited by the resistive interchange mode to low βN≤2.3. This mode is insensitive to the details of the rotational and the magnetic shear profiles. A new class of discharges, which has a broad region of weak or slightly negative magnetic shear (WNS), is described. The WNS discharges have broader pressure profiles and higher β values than the NCS discharges, together with high confinement and high fusion reactivity. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Hitherto, the relationship between malignancy-associated morphological features in single tumour cells and the expression of markers indicating functional properties of these cells remained widely unknown. This study was aimed at describing differences in the size, shape and chromatin structure between tumour cells with different marker expression for progesterone receptors (PgR) and p53. Two series of breast cancers, consisting of 50 PgR-positive, and 39 p53-negative and 49 p53-positive mammary carcinomas, were investigated. The immunohistochemical staining was performed on paraffin sections using 3-amino-9-ethylcarbazole as the chromogenic substrate. By means of a cytometry workstation equipped with a computer-controlled motorised scanning stage, about 500 positive and negative tumour cells in each case were localised in the microscope and categorised by a scoring system for their staining intensity. After destaining, the tissue sections were Feulgen-stained. Then, all the tumour cells were relocated automatically and analysed by high resolution image cytometry. Among the numerous size, shape, and texture features used in the system, several variables of the nuclear contour and chromatin structure were found to be significantly different between the positive and negative tumour cell populations. Nuclei without PgR had more malignancy-associated morphological features than PgR-positive cells. Whereas p53-negative nuclei had a higher degree of regularity, their positive counterparts exhibited higher DNA ploidy values.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric radiology 26 (1996), S. 750-753 
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective. The objective of this study was to evaluate the postoperative technetium-99m-labeled methylene diphosphonate (99mTc-MDP) scintigraphic appearance of limb-sparing procedures in patients treated for bone tumors.Materials and methods. We retrospectively reviewed the medical records and assessed planar bone scans, subjectively and semiquantitatively, of all patients treated with limb-sparing procedures at our institution who survived at least 1 year following resection of the primary lesion.Results. The operative sites of 20 of the evaluable 45 patients (44 %) demonstrated normal tracer avidity during follow-up (median 12 months). Nine patients (20 %) demonstrated normal avidity on their first follow-up bone scans (median 6 months). Coincident99mTc-MDP bone scans were obtained on 11 patients who developed 12 postoperative complications or injury during the study and accurately identified the lesion in eight (67 %).Conclusion. Although many patients have abnormal99mTc-MDP avidity in the operative site after limb-sparing surgery, almost half eventually have normalization of uptake. However, planar bone scans have limited use for assessing the primary tumor site postoperatively as persistent abnormal avidity may preclude detection of changes associated with development of postoperative complications.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1998
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Limb-sparing procedures utilizing endoprostheses improve both the quality of life and functional level of patients treated for primary bone sarcomas. Herein, we present the imaging findings of an uncommon cause of prosthetic failure, i. e., foreign body reaction, manifested by progressive multifocal osteolysis along the prosthetic femoral shaft.
    Type of Medium: Electronic Resource
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