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  • 1995-1999  (2)
  • 1996  (2)
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  • 1995-1999  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Histopathology 29 (1996), S. 0 
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report on two cases of low grade follicle centre cell lymphoma with a pronounced parafollicular monocytoid/marginal zone B-cell component. One patient had a history of preceeding follicular high grade B-cell lymphoma of centroblastic type showing the same light chain restriction and identical immunoglobulin heavy chain gene rearrangement as the low grade lymphoma diagnosed 15 months later. Morphologically, in both cases the two constituents of the low grade tumours were clearly distinguishable. Immunohistochemically, the follicular component strongly expressed bcl-2 protein in contrast to a weak staining of the marginal zone B-cell component. Performing PCR, a rearrangement of the major breakpoint region of bcl-2 was not found. Identical light chain restriction of the follicular and the monocytoid B-cell/marginal zone components strongly indicates a clonal relationship between them. A monocytoid/marginal zone B-cell component in follicular lymphoma probably results from differentiation of the follicle centre cells and does not indicate a composite lymphoma.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0942-0940
    Keywords: Electrical stimulation ; nerve ; neurography ; neuromonitoring ; brain stem ; cauda equina
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To facilitate use of various stimulation modes for intra-operative monitoring during neurosurgical procedures, we designed and produced a variable stimulation system that consists of a coaxial bipolar flush-tip insulated stimulation electrode, and a switch box to administer monopolar or bipolar stimulation through the same stimulation electrode. The electrode is composed of components that are readily available, so that its construction can be duplicated by others at minimal expense. For mapping of neural tissue during surgical procedures, we use the monopolar stimulation mode to identify relative large areas around the site of stimulation which are free of motor nerve fibres. The bipolar stimulation mode is most useful for precise localization of motor nerve fibres and in distinguishing motor from non-motor fibres.
    Type of Medium: Electronic Resource
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