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  • 1995-1999  (2)
  • 1999  (1)
  • 1997  (1)
  • Diagnostic radiology  (1)
  • Glucose tolerance  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Emergency radiology 4 (1997), S. 218-224 
    ISSN: 1438-1435
    Keywords: Diagnostic radiology ; Observer performance ; Spine injuries ; Spine, fractures ; Spine, radiography ; Trauma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We undertook this study to identify causes of false-negative cervical spine plain radiographic interpretations in a series of experimental readings. One hundred eighty-nine examinations (three views), including 97 patients with acute injuries and 92 normal controls from the same emergency room population, were presented to 14 radiologists. The false-negative rate was 17% (2646 readings). The most frequently missed injuries were laminar fractures, atlantoaxial subluxations, pillar fractures, and fractures of C1 and C2. Analysis of 38 cases with 47 fractures missed by two or more readers showed that 20 *43%) involved the C1–C2 area, and 14 (30%) involved the laminae, and articular pillars. Analysis revealed one or more possible contributing causes for the diagnostic error in 21 injuries: marked osteopenia (2), overlying structures (4), a combination of overexposure and overlying structures (2), and satisfaction of search (13). For 26 injuries (55%), no extrinsic cause was evident, and 23 of these (88%) involved the C1–C2 region or the laminar/articular pillar region.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1041
    Keywords: Key words Deflazacort ; Prednisone ; Glucose tolerance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Abstract Objective: To compare the diabetogenic effects of deflazacort (D) versus prednisone (PN) using a dosage ratio of 1.5 mg deflazacort:1 mg prednisone. Methods: Thirty-three patients suffering from various active connective tissue or chronic inflammatory diseases were randomized to be treated with D or PN, assuming a therapeutic equipotency ratio of 1.5 mg D:1 mg PN. Neither dosage nor glucocorticoid employed were modified during the study. Patients had not received steroid treatment during the month prior to their inclusion date. Fasting glucose, glycosilated haemoglobin and fructosamine were determined before and after 1 month of treatment. Non-diabetic patients were also submitted to an oral glucose tolerance test (OGTT) at entry and after 1 month. Results were compared by univariate, and multivariate tests to correct the effects of age, body mass index and diagnosis. Results: After 1 month of treatment there were no differences between D and PN in fasting glucose, glycosilated haemoglobin, or fructosamine. OGTT performed after treatment showed similar glucose values for both treatment groups. Patients treated with D had insulin levels at min 60 of the post-treatment OGTT which were higher than those treated with PN [114.1 (62.8) mcUI · ml−1 versus 73.5 (32.7) mcUI · ml−1, P = 0.049], but the difference lost its statistical significance in the multivariate analysis. Conclusion: D and PN have similar effects on glucose tolerance when an equipotency ratio of 1.5 mg D:1 mg PN is employed. Previous studies employing a ratio of 1.2:1 mg may have understimated the adverse effects of D on glucose metabolism.
    Type of Medium: Electronic Resource
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