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  • 1995-1999  (2)
  • 1997  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 52 (1997), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In a double-blind, placebo-controlled study we investigated the effect of a single pre-induction intravenous dose of dexmedetomidine 2 μg.kg−1 on anaesthetic requirements and peri-operative haemodynamic stability in 50 patients undergoing minor orthopaedic and general surgery. Patients were anaesthetised with nitrous oxide/oxygen/fentanyl, supplemented if necessary with isoflurane. The mean (SD) intra-operative isoflurane concentration was lower in the dexmedetomidine-treated patients than controls (0.01 (0.03)% compared to 0.1 (0.1)%; p = 0.001) although six of the 25 treated patients required isoflurane at some stage. The haemodynamic response to tracheal intubation and extubation was reduced in the dexmedetomidine group as was intra-operative heart rate variability; postoperative analgesic and anti-emetic requirements and peri-operative serum catecholamine concentrations were lower in the dexmedetomidine group. Hypotension and bradycardia occurred more frequently after dexmedetomidine.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Der Internist 38 (1997), S. 325-336 
    ISSN: 1432-1289
    Keywords: Schlüsselwörter Diagnostische Studien ; A-priori- Wahrscheinlichkeit ; Prävalenz ; Sensitivität ; Spezifität ; ROC-Analyse ; Prädiktive Werte ; Wirksamkeitsnachweis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zum Thema Die zur Diagnoseevaluierung methodisch-technischen und methodisch-diagnostischen Grundlagen werden in der vorliegenden Übersichtsarbeit dargelegt. In Analogie zur Beurteilung der Wirksamkeit von Therapiemaßnahmen wird ein vergleichbares Ordnungsprinzip für Diagnostikmaßnahmen vorgestellt. Der interessierte Leser findet grundsätzliche Begriffe der Statistik erläutert und im Detail auch statistische Formeln.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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