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  • 11
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    The @journal of product & brand management 8 (1999), S. 170-184 
    ISSN: 1061-0421
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Rather than taking the more traditional approach of measuring brand equity for accounting or strategic reasons, the approach taken here is concerned with optimizing brand equity through parsimonious manipulation of the marketing mix. To this end a macro-model is first developed; this model is then operationalized and tested (in terms of predicted versus actual brand share) in three Korean markets. The contribution of the paper lies in the development of a methodology through which management can efficiently build brand power in their markets. The statistical methods (factor analysis and preference regression) are commonly used in commercial research and the research requirements to build such a model are quite modest - the proposed model makes a theoretical contribution but can also be used as a practical managerial tool.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 22 (1999), S. 0 
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The object of this study is to establish a new test method for evaluating stress corrosion cracking (SCC) susceptibility of high-strength steel using a small punch (SP) test and acoustic emission (AE). A miniaturized specimen (10 × 10 × 0.5 mm) is adopted for SCC evaluation. The experiments are conducted at various loading rates and at various orientations of the specimen. The cumulative average amplitude of the AE signal per unit equivalent fracture strain (εqf ) increases as the SCC susceptibility increases. Through the load–displacement behaviour, the fracture energy (ESP ), the SEM fractographs, and the correlation between the SCC susceptibility and the AE characteristics, it is proved that the small punch test method combined with AE measurements is a useful method to evaluate the SCC susceptibility of high-strength steel.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Oxford BSL : Blackwell Science Ltd
    British journal of dermatology 139 (1998), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Fas, a cell surface receptor and member of the tumour necrosis factor receptor superfamily, induces apoptosis upon oligomerization by its ligand (Fas ligand: FasL). Detailed studies have revealed that Fas is broadly expressed in normal human tissues, but relatively little is known about the range of cell types capable of expressing FasL. The aim of this study was to determine the in vivo patterns of expression of Fas and FasL in human skin tissues. Immunohistochemistry was performed using paraffin-embedded samples of normal and neoplastic skin tissues. In normal skin, FasL was expressed in the epidermis, sebaceous glands, sweat glands and outer root sheath of the hair. In squamous cell carcinomas (SCC), all cases analysed expressed FasL at high levels, whereas 60% of basal cell carcinomas (BCC) were positive for FasL. Expression of Fas in normal skin was observed in the basal and spinous layers of the epidermis, the outer root sheath of the hair, and the sebaceous glands. Expression of Fas was observed in all the SCC tested and none of the BCC tested. Expression of FasL by normal cells and tumour cells in skin tissue, demonstrated for the first time in the present study, may provide an important clue to understanding skin physiology, and immune evasion of skin tumours.
    Type of Medium: Electronic Resource
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  • 14
    ISSN: 1574-695X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: In order to develop an effective means to treat and prevent Pseudomonas aeruginosa infections, we have purified P. aeruginosa outer membrane protein (Oprs)-specific human IgG antibody using a large-scale affinity column. In this study, we investigated the cross-protective activity of the purified anti-Oprs IgG against various immunotype strains of P. aeruginosa. The anti-Oprs IgG reacted with Oprs isolated from seven Fisher-Devlin immunotype strains of P. aeruginosa and was able to promote opsonophagocytic killing of all seven immunotype strains by human phagocytic cells. Administration of 500 μg anti-Oprs IgG to mice raised the LD50 of the P. aeruginosa strains by 8–250-fold, indicating the protective capacity against heterologous P. aeruginosa strains as well as homologous strains. In contrast, despite high titers against P. aeruginosa Oprs, total serum IgG isolated from burn patient sera was no better than normal serum IgG in protecting mice from infection with P. aeruginosa. These data demonstrate that the affinity-purified human anti-Oprs IgG could afford protection against heterologous immunotype P. aeruginosa strains and provide a rationale to use anti-Oprs IgG as an adjunct for treatment of P. aeruginosa infections in humans.
    Type of Medium: Electronic Resource
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  • 15
    ISSN: 1572-879X
    Keywords: 1-butene ; skeletal isomerization ; fluorine-modified alumina ; acid site concentration ; monomolecular reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract γ-alumina catalysts modified with different weight loadings of fluorine have been used for skeletal isomerization of 1-butene in order to investigate the effects of the fluorine loading level on the conversion of 1-butene and the selectivity to isobutene formation. Increasing the actual loading of fluorine up to 0.012 wt% led to an increase in conversion of 1-butene over fluorine-modified γ-alumina catalysts, while the high selectivity to isobutene remains almost unchanged. On the other hand, a clear trend of increasing 1-butene conversion with a decreasing selectivity to isobutene is observed for the γ-alumina catalysts with higher loadings of fluorine. An analysis of the results from the thermal analysis, NH3 temperature-programmed desorption, infrared and the 1-butene sorption measurments clearly indicates that the number of strong acid sites in the modified γ-alumina catalysts is greatly enhanced at fluorine loadings higher than 0.012 wt%, leading to the acceleration of 1-butene oligomerization followed by cracking to light hydrocarbons. Therefore, the 1-butene isomerization selectivity from fluorine-modified γ-alumina catalysts can be understood in terms of a competition between the monomolecular and bimolecular reaction pathways, which highly depend on the concentration of strong acid sites.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Springer
    Catalysis letters 57 (1999), S. 209-215 
    ISSN: 1572-879X
    Keywords: 1-butene ; skeletal isomerization ; mesoporous material ; acid site concentration ; monomolecular reaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract On the skeletal isomerization of 1-butene, mesoporous materials with mesopores too large to expect any shape selectivity have been used in order to investigate the effects of the concentration of acid sites on the conversion of 1-butene and the selectivity for isobutene. The concentrations of acid sites can be varied through the control of the Si/Al ratio. The conversion of 1-butene increases with increasing the aluminium content of mesoporous materials, while the selectivity for isobutene decreases. The results of ammonia TPD, IR measurement of 1-butene adsorption, and TG analysis of used catalysts indicate that distant location of activated 1-butene molecules induces the monomolecular reaction over the mesoporous materials with low aluminium content, resulting in high selectivity for skeletal isomerization. On the mesoporous material with high aluminium content, however, the high concentration of activated 1-butene molecules accelerates the multimolecular oligomerization and, thus, reduces the selectivity.
    Type of Medium: Electronic Resource
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  • 17
    ISSN: 1572-882X
    Keywords: LiCl/1 ; 3‐dimethy‐2‐imidazolidinone solvent system ; homogeneous cellulose solution ; cellulose acetate ; O‐methylcellulose ; reaction characteristics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract In order to elucidate the nature of the LiCl/1,3‐dimethy‐2‐imidazolidinone (DMI) solvent system as one of the homogeneous reaction media of cellulose, cellulose acetate (CA) and O‐methylcellulose (MC) were prepared using this solvent system, and the distribution of substituents within anhydroglucose units was examined by 13C‐NMR. It was found that (i) homogeneous cellulose solutions can be easily prepared by heating 2, 5–12 and 100 parts of weight of cellulose, LiCl, and DMI, respectively, and (ii) the relative reactivity of hydroxyl groups is in the order C‐6 〉 C‐2 〉 C‐3 for both CA and MC. A remarkable feature of this solvent system is that the reaction efficiency in etherification is very high compared with other homogeneous solvent systems.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    Springer
    Journal of statistical physics 92 (1998), S. 519-542 
    ISSN: 1572-9613
    Keywords: Conductance ; electron waveguide ; electron scattering ; Landauer formula
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Ballistic electron waveguides are open quantum systems that can be formed at very low temperatures at a GaAs/AlGaAs interface. Dissipation due to electron–phonon and electron–electron interactions in these systems is negligible. Although the electrons only interact with the walls of the waveguide, they can have a complicated spectrum including both positive energy bound states and quasibound states which appear as complex energy poles of the scattering S-matrix or energy Green's function. The quasibound states can give rise to zeros in the waveguide conductance as the energy of the electrons is varied. The width of the conduction zeros is determined by the lifetimes of the quasibound states. The “complex energy spectrum” associated with the quasibound states also governs the survival probability of electrons placed in the waveguide cavities.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 68 (1999), S. 417-423 
    ISSN: 1432-0630
    Keywords: PACS: 42.62.-b; 42.55.Lt; 42.30.Va
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 34 (1998), S. 1-5 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. The Spirostomum ambiguum toxicity test has been intensively studied in the Department of Environmental Health Sciences, Warsaw University of Medicine for the last 5 years. The purpose of the present work was to develop and evaluate a miniaturized microplate version of the test, called the Spirotox test, and to estimate the toxicity of selected inorganic compounds to the Spirostomum ambiguum. The test was carried out in conventional 24-well (6 × 4) polystyrene multiwell plate. Preliminary test was one control and 11 toxicant concentrations with two duplicates. Definitive test was one control and five toxicant concentrations with three duplicates per concentration. Dilution of the sample was made directly in the plate. Toxicity series of heavy metals based on 24-h LC50 may be established as follows: Cu 〉 Ag 〉 Hg 〉 Cr 〉 Cd 〉 Zn 〉 Ni 〉 Pb 〉 Co 〉 Mn. The series may be divided into four classes: extremely toxic: below 0.1 ppm (Cu, Ag, Hg); very toxic: 0.1–1.0 ppm (Cr, Cd, Zn, Ni); toxic: 1.0–10 ppm (Pb, Co); and low toxic: above 10 ppm (Mn). Anions were much less toxic to S. ambiguum than cations. Using the same classification, only cyanide (CN) was toxic, other anions were low toxic. Toxicity series based on 24-h LC50 may be established as follows: CN 〉 SeO3 〉 Cr2O7 〉 NO2 〉 S2O3 〉WO4 〉 BO3.
    Type of Medium: Electronic Resource
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