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  • 1995-1999  (3)
  • 1980-1984
  • 1965-1969
  • 1998  (3)
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  • 1995-1999  (3)
  • 1980-1984
  • 1965-1969
Year
  • 1
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To determine the proportion and nature of congenital anomalies in babies born to women exposed to newly marketed drugs during the first trimester.Design Non-interventional observational cohort studies.Methods The women were identified in confidence by the Prescription Pricing Authority. The doctor was sent a questionnaire to determine clinical events, including pregnancy, occurring after the drug was dispensed. A supplementary questionnaire determined the outcome of each reported pregnancy.Setting General medical practice in England.Population Women exposed to newly marketed drugs in whom pregnancy was recorded.Main outcome measures Outcomes of pregnancies, the proportion and nature of congenital anomalies in the babies born.Results 2511 pregnancies were reported. In 831 of these pregnancies a newly marketed drug had been taken during the first trimester and in 74 during the secondkhird trimester. The outcome was ascertained for 780 (94%) of these 831 pregnancies: 547 (66%) births; 10 (1%) ectopic pregnancies; 94 (11%) spontaneous miscarriages; 5 (〈 1%) missed abortions; 120 (14%0) legal abortions; and 4 (C 1%) intrauterine deaths. 557 infants were born, of whom 14 (2.5%) had congenital anomalies.Conclusions The proportion of live infants with a congenital abnormality born to mothers exposed to newly marketed drugs in the first trimester was similar to the percentage of congenital anomalies estimated by the Ofice for National Statistics. These data add valuable information to the safety database of these drugs.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Reaction kinetics and catalysis letters 65 (1998), S. 87-91 
    ISSN: 1588-2837
    Keywords: benzidine ; diphenylamine ; radical formation ; on zeolite
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Solutions of benzidine and diphenylamine in benzene produce cation radical on the surface of zeolite, γ-alumina, MoO3 and MoO3 doped γ-alumina and zeolite. MoO3 doped zeolite behaved much differently than V2O5 doped zeolite in presence of benzidine or diphenylamine in benzene.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1572-9540
    Keywords: Penning trap ; highly charged ions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract We describe how a single hydrogen-like ion (C5+) is prepared, cooled with the method of resistive cooling and non-destructively detected with the image-current technique in a cryogenic Penning trap at T = 4 K. The storage time for C5+-ions in the cryogenically pumped vacuum chamber is longer than six months. The experimental techniques of preparing, cooling and detecting highly-charged ions in a Penning trap are relevant for precision experiments such as g-factor measurements, mass spectroscopy and laser spectroscopy.
    Type of Medium: Electronic Resource
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