Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1995-1999  (4)
  • 1965-1969
  • 1955-1959
  • 1998  (4)
Source
Material
Years
  • 1995-1999  (4)
  • 1965-1969
  • 1955-1959
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Evolution of a Mammalian Promoter Through Changes in Patterns of Transcription Factor Binding (1998)
    Springer
    Journal of molecular evolution 46 (1998), S. 639-648 
    Details
    ISSN: 1432-1432
    Keywords: Key words: Transcription — Promoter — Regulatory element —Mus genus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. Previously, we identified evolutionarily derived changes in the pattern of nuclear factor binding to overlapping sites (termed A, B, and C, in proximal to distal order) within the promoter region of the murine D7Rp2e gene. In Mus domesticus, strong binding occurs at site B, with weak binding at sites A and C; in M. pahari, strong binding is observed at sites A and C, with weak binding at site B. The M. pahari-specific occupancy pattern is associated with repression of transcription. Presently, we have identified two interspecies changes, a single A → G substitution within site B and a 7-bp indel within site C, that are primary determinants of the interspecies differences. These mutations alter both the pattern of binding site occupancy and the ability to repress transcription. The results are discussed in terms of a model involving a dynamic equilibrium between states of binding site occupancy, the nature of which can be modified during evolution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006344
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Advertising and information costs: an empirical study (1998)
    Bingley : Emerald
    International journal of social economics 25 (1998), S. 1334 
    Details
    ISSN: 0306-8293
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: As pointed out previously by economists, the implicit demand for cost-saving information by potential buyers generates a derived demand for advertising by sellers. This study adds to the body of evidence that reveals the positive role of advertising in the market process. The evidence presented here suggests that sellers do respond to the higher time costs faced by transient populations by providing advertising qua information in a manner that minimizes the total cost of voluntary exchange.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1108/03068299810213945
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Regeneration of plantlets from cotyledon and embryonal axis explants of Vigna mungo L. Hepper (1998)
    Springer
    Plant cell, tissue and organ culture 55 (1998), S. 75-78 
    Details
    ISSN: 1573-5044
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Sexually mature black gram plantlets were efficiently regenerated from seed-derived cotyledon and embryonal axis explants.The explants were capable of producing multiple shoots when cultured on modified MS medium containing B5 vitamins supplemented with 6-benzylaminopurine (BAP) and α-naphthaleneacetic acid (NAA) within 15 days. The regenerated shoots were elongated on MS basal medium and rooted on MS medium containing indole-3-butyric acid (IBA). Rooted plantlets were transferred to soil with 75% success, where they attained sexual maturity and produced viable seeds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1026481310822
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    High-level Constitutive Expression of α1-acid Glycoprotein and Lack of Protection Against Tumor Necrosis Factor-induced Lethal Shock in Transgenic Mice (1998)
    Springer
    Transgenic research 7 (1998), S. 429-435 
    Details
    ISSN: 1573-9368
    Keywords: transgenic ; acute phase ; hepatitis ; cytokines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract α1-Acid glycoprotein (AGP) is an acute phase protein produced by hepatocytes. Although its exact biological function remains controversial, it was shown to protect galactosamine-sensitized or normal mice against hepatitis and lethal shock induced by tumor necrosis factor (TNF). Rat-AGP- transgenic mice, constitutively producing several mg AGP per ml serum were tested for their response to a combined challenge with TNF and D-(+)-galactosamine. A previously characterized, single transgenic line (9.5–5) was used. In contrast to our expectations both heterozygous or homozygous transgenic mice were not protected by the endogenously overproduced AGP. However, both transgenic and non-transgenic mice were protected by pretreatment with interleukin-1, an effect which we believe is mediated by the induction of acute phase proteins like AGP. Furthermore, both types of mice were protected by exogenous bovine AGP, suggesting that the lack of protection by endogenous AGP is not because of a repressed response to AGP. Finally, we demonstrate that purified AGP from the serum of transgenic mice is as protective as the AGP from non-transgenic mice or rats. The results suggest that AGP is protective only when its concentration is rapidly induced, perhaps because the endogenous steady state synthesis of AGP, in non-transgenic as well as transgenic mice, is coupled to the production of an AGP-binding factor. This study provides an interesting example of differences in outcome to a lethal challenge between an acute administered and a chronically produced protective protein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008810429645
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...