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  • 1
    Electronic Resource
    Electronic Resource
    Preparation and Absolute Configuration of (-)-(E)-α-trans-Bergamotenone (1998)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 81 (1998), S. 153-162 
    Details
    ISSN: 0018-019X
    Keywords: Chemistry ; Organic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The synthesis, absolute configuration, and olfactive evaluation of (-)-(E)-α-trans-bergamotenone (= (-)-(1′S,6′R,E)-5-(2′,6′-dimethylbicyclo[3.1.1]hept-2′-en-6′-yl)pent-3-en-2-one; (-)-1), as well as its homologue (-)-19 are reperted. The previously arbitrarily attributed absolute configuration of 1 and of (-)-α-trans-bergamotene (= (-)-(1 S,6R)-2,6-dimethyl-6-(4-methylpent-3-enyl)bicyclo[3.1. 1]hept-2-ene; (-)-2), together with those of the structurally related aldehydes (-)-3a,b and alcohols (-)-4a,b, have been rigorously assigned.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/hlca.19980810114
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Röntgenstrukturanalyse großer Biomoleküle (1998)
    Weinheim : Wiley-Blackwell
    Chemie in unserer Zeit 32 (1998), S. 22-33 
    Details
    ISSN: 0009-2851
    Keywords: Chemistry ; Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Crystallography is a powerful tool for the determination of three-dimensional structures of large biomolecules. In recent years, the number of published crystal structures has dramatically increased. this is due in part to the knowledge on the three-dimensional structure to the general understanding of biochemical processes is demonstrated for three selected examples. Crystal structures of human growth hormone bound to receptor peptides strongly suggests a general principle of receptor-mediated signal transduction. A self-splicing RNA nitron, seen in three dimensions, reveals general folding patterns in nucleic acids. Finally, HIV protease is discussed as a paradigm for structure-based drug design.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ciuz.19980320105
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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