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  • 1
    Electronic Resource
    Electronic Resource
    Development of a two-dimensional space-resolved high speed sampling camera : Proceedings of the 12th topical conference on high temperature plasma diagnostics (1999)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 625-628 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We developed a two-dimensional spatial resolved high-speed UV sampling camera (HISAC) to study energy transport in laser-produced plasmas. The HISAC is composed of an optical bundle of fibers coupled to a streak camera to obtain a two-dimensional spatial resolution with a temporal resolution of less than a few 10 ps. This HISAC system was demonstrated in the experiments on inferred uniformity measurements of laser-ablation pressures as well as on energy transport in ultraintense laser-plasma interactions. Two-dimensional shock heating was temporally resolved in a hemispherical target, resulting in the distribution of the ablation pressure as a function of laser incidence angle. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1149383
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  • 2
    Electronic Resource
    Electronic Resource
    Dielectric relaxation of water and heavy water in the whole fluid phase (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 3026-3036 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Recently we developed a new microwave spectroscopy technique in the frequency range up to 40 GHz, and measured the static dielectric constant and the dielectric relaxation time for supercritical water. In the present work we report the dielectric properties of heavy water at temperatures and pressures up to 770 K and 59 MPa, respectively. The static dielectric constant of D2O as well as H2O are well described by the Uematsu–Franck formula when the number density instead of the mass density is used as the input parameter. The dielectric relaxation time decreases rapidly with increasing temperature in liquid H2O and D2O and jumps to a large value at the liquid–gas transition. The relaxation time of D2O is longer than that of H2O in the liquid state, and the difference becomes smaller with decreasing density in the gaseous state. For both H2O and D2O the most relevant parameter determining the relaxation time is the temperature at high densities or at low temperatures, and it is the density at low densities or at high temperatures. Based upon the observation that the dielectric relaxation time becomes fairly long in the dilute limit, we have concluded that the dielectric relaxation in the gaseous state is governed by the binary collision of water molecules and explained the relaxation time quantitatively by the collision time. We have extended the interpretation of the dielectric relaxation to the liquid state by taking into account the contribution of bound water molecules that are incorporated in the hydrogen-bond network. Anomalous relaxation at low temperatures is also discussed. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.477897
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  • 3
    Electronic Resource
    Electronic Resource
    A slow mode wave as a possible source of Pi 2 and associated particle precipitation: a case study (1999)
    Springer
    Annales geophysicae 17 (1999), S. 674-681 
    Details
    ISSN: 0992-7689
    Keywords: Magnetospheric physics (auroral phenomena; energetic particles, precipitating; MHD waves and instabilities)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract An intensification of auroral luminosity referred to as an auroral break-up often accompanies the onset of geomagnetic pulsation (Pi 2) at the dip-equator. One such auroral break-up occurred at 2239 UT on 16 June, 1986, being accompanied by weak substorm activity (AE≈50 nT) which was recorded in all-sky image of Syowa Station, Antarctica (66.2°S, 71.8°E in geomagnetic coordinates). The associated Pi 2 magnetic pulsation was detected by a fluxgate magnetometer in the afternoon sector at the dip-equator (Huancayo, Peru; 1.44°N, 355.9° in geomagnetic coordinates; 12.1°S, 75.2°W in geographic coordinates; L = 1.00). In spite of the large separation of the two stations in longitude and latitude, the auroral break-up and subsequent luminosity modulation were seen to be correlated with the wave form of the ground Pi 2 pulsation. This occurred in such a way that the luminosity maximum was seen to occur at the phase of maximum amplitudes of Pi 2 wave form. We argue that the observed correlation could be interpreted as indicating a Pi 2-modulation of a field-aligned acceleration of the low energy electrons that may occur near the equator of the midnight magnetosphere.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s00585-999-0674-4
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  • 4
    Electronic Resource
    Electronic Resource
    Association between M/L55-polymorphism of paraoxonase enzyme and oxidative DNA damage in patients with type 2 diabetes mellitus and in control subjects (1999)
    Springer
    Human genetics 〈Berlin〉 105 (1999), S. 179-180 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. The paraoxonase enzyme (PON) gene polymorphism causes a change of methionine (M-allele) to leucine (L-allele). PON may reduce low density lipoprotein oxidation and prevent atherosclerosis. Urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a sensitive index of oxidative DNA damage. We have studied the association between the PON genotypes and the urinary excretion of 8-OHdG. The study population consisted of 93 Finnish type 2 diabetes patients and 106 non-diabetic control subjects. The 24-h excretion of 8-OHdG was significantly higher in diabetic patients than in control subjects (P〈0.001). In control subjects, the ratio of the 8-OHdG/glomerular filtration rate increased in order of genotype from MM to ML to LL (P〈0.0412). These results suggest that lipid peroxidation may have an effect on DNA oxidation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004399900074
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  • 5
    Electronic Resource
    Electronic Resource
    Streptococcus intermedius-brain abscess in chronic granulomatous disease (1999)
    Springer
    European journal of pediatrics 158 (1999), S. 872-873 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310051231
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  • 6
    Electronic Resource
    Electronic Resource
    Nitric oxide increases the amount of murine cytomegalovirus-DNA in mice latently infected with the virus (1999)
    Springer
    Archives of virology 144 (1999), S. 2273-2290 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary.  At 5 wk after the intraperitoneal infection of murine cytomegalovirus (MCMV) in adult (C3H/He × BALB/c) F1 (CBF1) mice, MCMV-DNA was noted mainly in the salivary glands (SG). Since graft-versus-host reaction (GVHR) is well known as a major risk factor for CMV reactivation, parental BALB/c spleen cells were then intravenously transferred to these mice to induce GVHR. A high copy number of full-length MCMV-DNA was thus observed in the lungs as well as the hearts and livers at 4 to 6 wk after the cell transfer, whereas the copy numbers in SG after the cell transfer were comparable to those before the transfer. It was therefore suggested that the amount of MCMV-DNA noted in these organs had been increased by GVHR. However, no transcripts of MCMV-DNA could be detected. Since a marked expression of mRNA of inducible nitric oxide synthetase (iNOS) was noted in the lungs and the hearts during the course of GVHR, the role of NO in the increase of MCMV-DNA after the cell transfer was next examined. The administration of L-arginine, a substrate for NO, increased the amount of MCMV-DNA in the lungs and the hearts after the induction of GVHR. In contrast, the material which suppressed iNOS induction inhibited the emergence of MCMV-DNA. Therefore, the NO generated during the course of GVHR increased the amount of the viral DNA in the lungs and the hearts of the mice latently infected with MCMV. If the increase in the amount of viral genome is the initial step of viral reactivation from the latent state, then NO would thus trigger the initial step of the reactivation of the DNA virus. As the lungs are the major organ to produce NO after systemic stimulation, the observations of this study may explain why the lungs are the major site of CMV latency and why GVHR triggers CMV reactivation. These findings are thus considered to demonstrate that NO plays a novel role in viral infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007050050644
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  • 7
    Electronic Resource
    Electronic Resource
    Medication-induced hallucination and cerebral blood flow in Parkinson’s disease (1999)
    Springer
    Journal of neurology 246 (1999), S. 365-368 
    Details
    ISSN: 1432-1459
    Keywords: Key words Hallucination ; Parkinson’s disease ; Cerebral blood flow ; Single photon emission ; computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although hallucinations in Parkinson’s disease (PD) are not unusual in the long-term treatment with anti-parkinsonian agents, their mechanism is not fully understood. We compared both the neuropsychiatric state and the results of 99mTc-labeled hexamethyl propyleneamine oxime single-photon emission computed tomography in 12 PD patients with medication-induced hallucinations and 21 PD patients without hallucinations. Hallucinatory patients showed significantly lower cerebral blood flow in left temporal regions than nonhallucinatory patients. The cerebral blood flow reduction in these regions may be related to the mechanism of medication-induced hallucinations in PD.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004150050364
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