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  • 1995-1999  (2)
  • 1955-1959
  • 1999  (2)
  • Schlüsselwörter:Sicherheitsarchitektur, Mehrseitige Sicherheit, Konfigurierung, Aushandlung, Interoperabilität  (1)
  • Chemistry
  • NADPH-diaphorase
  • preimplantation diagnosis
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Informatik, Forschung und Entwicklung 14 (1999), S. 95-108 
    ISSN: 0949-2925
    Keywords: Schlüsselwörter:Sicherheitsarchitektur, Mehrseitige Sicherheit, Konfigurierung, Aushandlung, Interoperabilität ; Key words: Security architecture, multilateral security, configuration, negotiation, interoperability ; CR Subject Classifications: C.2.4, H.5.2, K.4.4, K.6.5
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Abstract. We present a prototype of a security architecture. It enables developers and users of distributed applications to employ multilateral security. Users can express their security goals (e.g. confidentiality, anonymity, integrity and accountability) and select the according cryptographic mechanisms. The communicating parties negotiate security goals and mechanisms to secure the communication. Therefore the architecture comprises components for configuration and negotiation as well as so called security gateways. Building on secure local systems it allows to set up flexible multilateral security for distributed applications.
    Notes: Zusammenfassung. Wir stellen eine prototypische Implementierung einer Sicherheitsarchitektur vor. Sie unterstützt Nutzer und Entwickler verteilter Anwendungen bei der Umsetzung bzw. Integration von mehrseitiger Sicherheit. Nutzer können Schutzziele wie Vertraulichkeit, Anonymität, Integrität und Zurechenbarkeit anwendungsbezogen formulieren und ihnen zugeordnete kryptographische Mechanismen konfigurieren. Der konkrete Schutz einer Kommunikation über Datennetze wird zwischen den Partnern ausgehandelt. Heterogenen Anforderungen der Nutzer bzw. Applikationen und heterogenen Eigenschaften der Schutzmechanismen wird durch Architekturkomponenten für Konfigurierung und Aushandlung sowie sog. Sicherheitsgateways Rechnung getragen. Die Architektur setzt jeweils lokal sichere Basissysteme voraus und ermöglicht darauf aufbauend flexible mehrseitige Sicherheit für verteilte Anwendungen.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-7330
    Keywords: preimplantation diagnosis ; chromosome 13, 18, and 21 aneuploidies ; FISH ; first and second polar bodies ; IVF
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: We previously demonstrated that aneuploidy-free oocytes may be preselected by testing the first and second polar bodies removed from oocytes following their maturation and fertilization. The present paper describes the results of the application of the method in 659 in vitro fertilization cycles from patients of advanced maternal age. Methods: Using micromanipulation techniques, 3943 oocytes were tested by polar body sampling and fluorescent in situ hybridization analysis using specific probes for chromosomes 13, 18, and 21. Results: Fluorescent in situ hybridization results were available for 3217 (81.6%) of 3943 oocytes studied, of which 1388 (43.1%) had aneuploidies; 35.7% of the aneuploidies were of first meiotic division origin, and 26.1% of second meiotic division origin. Most errors in the first meiotic division were represented by chromatid malsegregation. The transfer of embryos deriving from 1558 of 1829 aneuploidy-free oocytes in 614 treatment cycles resulted in 131 clinical pregnancies and 88 healthy children born after confirmation of the polar body diagnosis. Conclusions: Polar body testing of oocytes provides an accurate and reliable approach for prevention of age-related aneuploidies in in vitro fertilization patients of advanced maternal age.
    Type of Medium: Electronic Resource
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