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  • 1995-1999  (2)
  • 1999  (2)
  • Key Words. Kinesin; kinesin-like proteins; microtubule-based motors; axonal transport; neurons.  (1)
  • Phenotype  (1)
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Years
  • 1995-1999  (2)
Year
  • 1999  (2)
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Acute myeloid leukemia M2 and t(8;21)(q22;q22) with an unusual phenotype: myeloperoxidase (+), CD13 (–), CD14 (–), and CD33 (–) (1999)
    Springer
    Annals of hematology 78 (1999), S. 237-240 
    Details
    ISSN: 1432-0584
    Keywords: Key words Acute myeloid leukemia ; Phenotype ; t(8;21)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Cases of myeloid surface antigen-negative acute myeloid leukemia (AML) are rare. We describe the morphological, cytochemical, immunologic, and cytogenetic features of two patients with AML with maturation (FAB M2) and the phenotype MPO+, CD13 (–), CD33(–), CD56(+). Cytogenetic studies demonstrated t(8;21)(q22;q22). These findings suggest an association between the lack of CD13 and CD33 in myeloperoxidase-positive AML and the presence of t(8;21).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002770050508
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Kinesins in the nervous system (1999)
    Springer
    Cellular and molecular life sciences 56 (1999), S. 200-216 
    Details
    ISSN: 1420-9071
    Keywords: Key Words. Kinesin; kinesin-like proteins; microtubule-based motors; axonal transport; neurons.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Both the development and the maintenance of neurons require a great deal of active cytoplasmic transport. Much of this transport is driven by microtubule motor proteins. Membranous organelles and other macromolecular assemblies bind motor proteins that then use cycles of adenosine 5′-triphosphate hydrolysis to move these ‘cargoes’ along microtubules. Different sets of cargoes are transported to distinct locations in the cell. The resulting differential distribution of materials almost certainly plays an important part in generating polarized neuronal morphologies and in maintaining their vectorial signalling activities. A number of different microtubule motor proteins function in neurons; presumably they are specialized for accomplishing different transport tasks. Questions about specific motor functions and the functional relationships between different motors present a great challenge. The answers will provide a much deeper understanding of fundamental transport mechanisms, as well as how these mechanisms are used to generate and sustain cellular asymmetries.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000180050422
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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