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  • 1
    Electronic Resource
    Electronic Resource
    Sporotrichoid presentations in leprosy (2000)
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 25 (2000), S. 0 
    Details
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Two adult patients of leprosy, one woman and one man, presented with a clinical picture simulating sporotrichosis. The skin and regional nerve trunk was affected in one, and in the other the disease was confined to the nerve. Both had features of an upgrading reaction following anti-leprosy therapy; this was seen as erosion and scarring of the plaque, and acute onset of abscesses along the easily palpable and thickened nerve that ruptured through the skin. The diagnosis was supported by histopathology. In the light of other infections that give rise to a sporotrichoid pattern of infection it is concluded that leprosy should also be included in this category so that early diagnosis and use of corticosteroids can be implemented quickly to prevent nerve destruction.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2230.2000.00623.x
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  • 2
    Electronic Resource
    Electronic Resource
    Synthesis and phosphorylation of androgen receptor of the mouse brain cortex and their regulation by sex steroids during aging (2000)
    Springer
    Molecular and cellular biochemistry 203 (2000), S. 95-101 
    Details
    ISSN: 1573-4919
    Keywords: aging ; AR phosphorylation ; AR synthesis ; brain cortex ; sex steroids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract To examine the synthesis and phosphorylation of androgen receptor (AR) and their regulation by sex steroids, adult (24 weeks) and old (65 weeks) male and female mice were gonadectomized and administered with testosterone and estradiol. AR amount, synthesis and phosphorylation were measured in the brain cortex by immunoblotting and immunoprecipitation using antibody raised against rat AR transactivation domain (TAD) which was expressed in E. coli as a fusion protein. We found that the amount of AR was high in adult and declined in old mice of both sexes. Administration of testosterone and estradiol significantly down-regulated the level of AR in old male and adult female. Similarly, the rate of AR synthesis also declined with age. Exogenous treatment of gonadectomized mice with testosterone and estradiol reduced the extent of synthesis significantly in all groups except in old female. No sex-dependent variation was noticed either in the level or synthesis of AR. In contrast, the extent of phosphorylation was higher in old mice of both sexes as compared to their adult counterparts. Testosterone and estradiol supplementation resulted in remarkable increase in AR phosphorylation in all groups. Thus it is evident from our findings that the amount and synthesis of AR decrease but phosphorylation of AR increases in the brain cortex with advancing age of mice and they are regulated by testosterone and estradiol in age and sex-specific manner.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007064307220
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    An analysis of the role of grain size on superplasticity of γ titanium aluminides (2000)
    Springer
    Journal of materials science 35 (2000), S. 147-151 
    Details
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The superplastic data for several microcrystalline and submicrocrystalline TiAl alloys has been analyzed to establish the rate controlling mechanism. The results show that the lattice diffusion controlled slip-accommodated grain boundary sliding mechanism is operative for the entire grain size range, 150 nm–20 μm. The detail of the nature of α2 phase, i.e. ordered or disordered, does not influence the kinetics of superplastic flow. The optimum superplastic temperature decreases with the decrease in grain size. The optimum superplastic flow stress shows an intrinsic inverse dependence on the grain size. This grain size dependence of the optimum superplastic flow stress can be explained as the stress required to nucleate dislocations from grain boundary edge during slip accommodation of grain boundary sliding. Superplasticity in nanocrystalline TiAl remains an intriguing possibility because it has the potential for increasing the optimal superplastic strain rate or alternatively, decreasing the superplastic forming temperatures.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004713220757
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Landslide hazard susceptibility mapping based on terrain and climatic factors for tropical monsoon regions (2000)
    Springer
    Bulletin of engineering geology and the environment 58 (2000), S. 275-287 
    Details
    ISSN: 1435-9537
    Keywords: Key words Residual material ; Colluvium ; Basalt ; Monsoon area ; Weightings ; Landslide hazard zonation ; Mots clés Formations résiduelles ; Colluvions ; Basalte ; Région de mousson ; Zonage de l'aléa ; Glissement de terrain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Résumé Une altération météorique intense du substratum, des formations résiduelles et colluvions, des intensités de pluies aléatoires, sont les principaux facteurs responsables des glissements de terrain dans les régions tropicales de mousson. Les conditions d'un développement durable de ces régions nécessitent des informations sur la répartition spatiale des zones sujettes aux glissements de terrain. Ces facteurs ne sont pas pris en considération dans la pratique de la cartographie de l'aléa glissement de terrain. Cette étude met en lumière divers aspects propres aux glissements qui ont lieu sur la côte ouest de l'Inde, ainsi que la méthodologie développée pour cet objectif.
    Notes: Abstract  Deep weathering, residual material (colluvium) and random rainfall intensity are mainly responsible for landslides in tropical monsoon regions. These parameters are often not taken into consideration in a landslide susceptibility assessment. Sustainable resources development in this region requires information on the spatial distribution of areas susceptible to landslides. This study highlights various aspects of the landslides that take place on the west coast of India and a methodology developed for landslide susceptibility mapping.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100649900032
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  • 5
    Electronic Resource
    Electronic Resource
    Bianchi Cosmologies with Particle Creation and Bulk Viscosity (2000)
    Springer
    General relativity and gravitation 32 (2000), S. 1429-1438 
    Details
    ISSN: 1572-9532
    Keywords: Open thermodynamic systems ; Bianchi cosmologies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract In the context of open thermodynamic systems, we study in this paper the evolution of Bianchi cosmologies with time-dependent bulk viscosity and particle production. The possibility of an initial non-singularity occurs with a suitable choice of parameters as seen in the case of FRW models [Desikan, K. (1997). Gen. Rel. Grav. 29, 435.].
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1001977415807
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Cosmologies with Variable G and Λ from Action Principle (2000)
    Springer
    General relativity and gravitation 32 (2000), S. 1439-1447 
    Details
    ISSN: 1572-9532
    Keywords: Variable gravitation constant ; variable
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Cosmologies with variable G and Λ are developed in this paper from an action principle, and some exact cosmological models are presented. These models indicate that the era of variable G and Λ must have occurred, if at all, prior to other possible eras like radiation and dust.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1001973832645
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    Paper (German National Licenses)
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