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  • 2000-2004  (8)
  • 1970-1974
  • 1965-1969
  • 2000  (8)
  • 1
    Electronic Resource
    Electronic Resource
    A reply (2000)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 55 (2000), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2000.01557-35.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Speed of onset of regional analgesia in labour: a comparison of the epidural and spinal routes (2000)
    Oxford : Blackwell Science Ltd
    Anaesthesia 55 (2000), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study compares the speed of onset of effective analgesia in two randomly assigned groups of patients requesting analgesia in labour. Patients in the combined spinal–epidural group (n = 69) were given a subarachnoid injection of 1.5 ml containing bupivacaine 2.5 mg and fentanyl 25 μg for initiation of analgesia. Patients in the epidural group (n = 73) were given an epidural injection of 10 ml containing bupivacaine 12.5 mg and fentanyl 50 μg. Mean (SD) onset times to the first pain-free contraction were 10.0 (5.7) min in the combined spinal–epidural group and 12.1 (6.5) min in the epidural group (p = 0.054). Patients in the combined spinal–epidural group suffered a higher incidence of motor weakness and proprioceptive deficit than those in the epidural group (p = 0.01). The incidence of technique failure and side-effects was similar in the two groups. It is our contention that the statistically nonsignificant difference in onset times does not justify the additional potential for side-effects and the extra cost of the equipment involved in the combined spinal–epidural technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2000.01071.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    A controlled study of relative periodontal attachment loss in people with HIV infection (2000)
    Copenhagen : Munksgaard International Publishers
    Journal of clinical periodontology 27 (2000), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective: To compare the progression of periodontal destruction in people with and without HIV.Method: Relative attachment loss on 6 index teeth was compared between 19 people with HIV and 17 people without HIV infection over 12 and 18 month follow ups.Results: The proportions of sites with 1, 2 or 3 mm of relative attachment loss were similar in the study and control groups. Mean maximum relative attachment loss was similar in both groups after 12 months but greater in the study group after 18 months.Conclusions: The data are not compelling evidence of greater periodontal destruction associated with HIV infection. Large scale cohort studies or meta-analyses would be more conclusive.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-051x.2000.027004273.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Predictors of tobacco and alcohol consumption and their relevance to oral cancer control amongst people from minority ethnic communities in the South Thames health region, England (2000)
    Copenhagen : Munksgaard International Publishers
    Journal of oral pathology & medicine 29 (2000), S. 0 
    Details
    ISSN: 1600-0714
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The purpose of this study was to examine the determinants of the health behaviour of ethnic groups in relation to alcohol and tobacco use. A cross-sectional questionnaire survey was carried out using network sampling amongst community groups in the South Thames region of the United Kingdom. Self-classified ethnic groups were identified: Black-African; Black–Caribbean; Indian; Pakistani; Bangladeshi and Chinese/Vietnamese. A total of 1113 people were recruited in the study. In all of the ethnic groups, men were more likely than women to smoke tobacco. Chewing of pan and tobacco was common in the South Asian communities and alcohol consumption was high among the Black–Caribbean group. Those factors were predicted by education, employment, gender and being born in the UK. It is important to examine the determinants of such risk behaviours in order to aid appropriate targeting of health promotion interventions, particularly those related to cancer control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0714.2000.290504.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Pore Characterisation and Interconnectivity Studies on Bioactive 58 S Sol-Gel Glass (2000)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 192-195 (Sept. 2000), p. 625-628 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/45/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.192-195.625.pdf
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  • 6
    Electronic Resource
    Electronic Resource
    Differential effect of FBN1 mutations on in vitro proteolysis of recombinant fibrillin-1 fragments (2000)
    Springer
    Human genetics 〈Berlin〉 107 (2000), S. 216-224 
    Details
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Mutations in the fibrillin-1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant disorder of connective tissue with highly variable clinical manifestations. FBN1 contains 47 epidermal growth factor (EGF)-like modules, 43 of which display a consensus sequence for calcium binding (cbEGF). Calcium binding by cbEGF modules is thought to be essential for the conformation and stability of fibrillin-1. Missense mutations in cbEGF modules are the most common mutations found in MFS and generally affect one of the six highly conserved cysteines or residues of the calcium-binding consensus sequence. We have generated a series of recombinant fibrillin-1 fragments containing six cbEGF modules (cbEGF nos. 15–20) with various mutations at different positions of cbEGF module no. 17, which is known to contain a cryptic cleavage site for trypsin. A mutation affecting a residue of the calcium-binding consensus sequence (K1300E) found in a patient with relatively mild clinical manifestations of classic MFS caused a modest increase in susceptibility to in vitro proteolysis by trypsin, whereas a mutation affecting the sixth cysteine residue of the same cbEGF module (C1320S) reported in a severely affected patient caused a dramatic increase in susceptibility to in vitro proteolysis by trypsin. A mutation at the cryptic cleavage site for trypsin abolished sensitivity of wild-type fragments and fragments containing K1300E to trypsin proteolysis. Whereas the relevance of in vitro proteolysis to the in vivo pathogenesis of MFS remains unclear, our findings demonstrate that individual mutations in cbEGF modules can affect these modules differentially and may suggest an explanation for some genotype-phenotype relationships in MFS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004390000368
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Pancreatitis: computed tomography and magnetic resonance imaging (2000)
    Springer
    European radiology 10 (2000), S. 401-408 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Computed tomography – Magnetic resonance imaging – Acute pancreatitis – Chronic pancreatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The value of CT in management of severe acute pancreatitis is well established. Some, but not all, experimental studies suggest a detrimental effect of intravenous iodinated contrast agents in acute pancreatitis, but although initial clinical data tends to support this, the positive advantages of enhanced CT outweigh the possible risks. Magnetic resonance imaging has been shown to be as effective as CT in demonstrating the presence and extent of pancreatic necrosis and fluid collections, and probably superior in indicating the suitability of such collections for percutaneous drainage. Image-guided intervention remains a key approach in the management of severely ill patients, and the indications, techniques and results of radiological intervention are reviewed herein. Both CT and MRI can be used to diagnose advanced chronic pancreatitis, with the recent addition of MRCP as a viable alternative to diagnostic endoscopic retrograde cholangiopancreatography (ERCP). Both MRCP and CT/MR imaging of the pancreatic parenchyma still have limitations in the recognition of the earliest changes of chronic pancreatitis – for which ERCP and tests of pancreatic function remain more sensitive – but the clinical significance of these minor changes remains contentious.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050066
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Poor results of distal trapezium resection for trapeziometacarpal-1 osteoarthritis (2000)
    Springer
    European journal of plastic surgery 23 (2000), S. 227-231 
    Details
    ISSN: 1435-0130
    Keywords: Key words Trapeziometacarpal-1 ; Osteoarthritis ; Distal trapezium resection ; Failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Eleven patients (mean age 54 years, range 46–67 years) with osteoarthritis limited to the trapeziometacarpal-1 joint underwent a distal trapezium resection. In nine cases the palmaris longus tendon and in two cases a Swanson condylar implant was used as interposition material. The results were very disappointing. Only one patient was satisfied. Nine patients were reoperated upon (mean interval period 43 months, range 3–110) because of pain. In two cases, the cause was dislocation of the Swanson condylar implant. In the other seven cases, prominent bone on the trapezium, ulnar osteophytes, scaphotrapezial osteoarthritis, sclerosis of the trapezium remnant, and impingement were causal factors. In future, the selection of patients for this operation will be performed with even greater care. Despite these poor results, a definitive conclusion about the indication for this procedure can only be made after evaluation of an improved operative procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002380050257
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