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Picosecond time-resolved x-ray diffraction probe of coherent lattice dynamics (abstract) (invited) : Papers from the 12th National Synchrotron Radiation Instrumentation Conference (2002)

Reis, D. A. ; DeCamp, M. F. ; Bucksbaum, P. H. ; [et al.]

[S.l.] : American Institute of Physics (AIP)

Review of Scientific Instruments 73 (2002), S. 1361-1361

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ISSN: 1089-7623

Source: AIP Digital Archive

Topics: Physics , Electrical Engineering, Measurement and Control Technology

Notes: The short pulses of hard x rays from synchrotron and laser based sources are sensitive probes of lattice dynamics on an ultrafast time scale. Using pump–probe time-resolved x-ray diffraction, we are able to follow the propagation of a picosecond coherent acoustic pulse in an ultrafast laser-strained single crystal. Comparison of the data with dynamical diffraction simulations allows for the quantitative determination of both the surface and bulk components of the associated strain. This technique is scalable to femtosecond and shorter time scales as x-ray pulses become shorter in duration, such as in fourth generation light sources. In addition, the diffraction of x rays off of coherent optical phonons may lead to the production of a femtosecond x-ray switch. © 2002 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1448147

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Effects of a bleaching agent containing 35% carbamide peroxide on the immunolocalization of cyclin D and p16 (2002)

GOMEZ, R. S. ; De CASTRO ALBUQUERQUE, R. ; DUTRA, R. A. ; [et al.]

Oxford, UK : Blackwell Science Ltd

Journal of oral rehabilitation 29 (2002), S. 0

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ISSN: 1365-2842

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Summary The evidences that p16 and cyclin D alterations occur in the earlier stages of many human cancers and that its immunolocalization can be used to study the cell cycle regulation, coupled with the possibility that chronic use of carbamide peroxide would induce DNA damage and cell cycle alteration, prompted us to analyse the effect of carbamide peroxide on the immunolocalization of these proteins in rat oral mucosa. Ten male Wistar rats were selected and submitted to topical application of 35% carbamide peroxide over buccal mucosa. The procedures were carried out twice a week for 3 months consecutively. The animals were killed after the last treatment and the buccal mucosa was removed and stored at −70 °C. Only distilled water was applied over the buccal mucosa of the control animals. The biotin–streptavidin amplified system was used for identification of cyclin D and p16 antigens and the percentage of basal and suprabasal cells positive for each one were obtained. The results did not show any difference between the experimental and control groups regarding the immunolocalization of cyclin D and p16. In conclusion, the present study showed that chronic use of carbamide peroxide does not induce cell cycle alteration in the oral mucosa of rats.