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  • 2000-2004  (7)
  • 2004  (7)
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  • 2000-2004  (7)
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  • 1
    Electronic Resource
    Electronic Resource
    Soft press: the ultra-low pressure molding technology for powder cosmetics (2004)
    Oxford, UK : Blackwell Science Ltd
    International journal of cosmetic science 26 (2004), S. 0 
    Details
    ISSN: 1468-2494
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Pressed-powder cosmetics with an extremely soft and light sense of touch were prepared using a novel ultra-low pressure molding technology. These novel pressed-powder cosmetics have a very high porosity creating a light silky feeling. Furthermore, with this novel molding, large quantities of organic crystalline powder can be incorporated into the cosmetics resulting in a good spreadability and smooth sense of touch. The novel molding technology named soft press molding developed in the current study involves several characteristic stages: (i) mixing the binder dispersion; (ii) soft compression; and (iii) drying (volatilizing a disperse medium). The first process is the mixing of water-repellent powder with an aqueous dispersion of elastic film-forming polymer into a pendular or funicular state. After compressing and drying, an interspersed polymer effectively combines the particles forming contact between the particles. In this study, calcium lauroyl taurate (CaLT) was used as an example of an organic crystalline powder to provide a silky smooth sense of touch to a powdery foundation. CaLT particles deform to a thin layer readily when applied to skin, creating a smooth pleasing sensation while spreading. Conventional high-pressure molding causes deformation during compression resulting in hard-caking of the molded cosmetics. However, by using soft press molding, the powdery foundation can contain more than 30 wt% of CaLT without hard-caking, and the resultant powdery foundation expresses an extremely smooth sensation to the touch. Furthermore, this powdery foundation shows a natural finish approximating bare skin due to the deformation of a thin layer on application restricting the light scattering, a characteristic property of a powder.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1467-2494.2004.00244_1.x
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  • 2
    Electronic Resource
    Electronic Resource
    Human airway submucosal glands augment eosinophil chemotaxis during rhinovirus infection (2004)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 34 (2004), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Asthma exacerbations are frequently associated with rhinovirus (RV) infections. However, the contribution of airway submucosal gland (SMG) to exacerbations of asthma in RV respiratory infection has not been studied.Objective This study was undertaken to examine whether RV-infected human respiratory SMG cells produce pro-inflammatory cytokines and chemokines for eosinophils, and augment eosinophil transmigration across human airway epithelium.Methods We infected cultured human tracheal SMG cells with RV14, collected culture media at 1, 3, and 5 days after infection, and measured the chemotactic activity for eosinophils in the culture supernatant using a 48-well microchemotaxis chamber and a 51Cr-labelled eosinophil transmigration assay.Results Exposing a confluent human tracheal SMG cell monolayer to RV14 consistently led to infection. Human SMG cells with RV infection secreted soluble factors activating human eosinophil chemotaxis into the culture supernatant in a time-dependent manner, and the culture supernatant significantly augmented the transmigration of 51Cr-labelled eosinophils through human airway epithelial cell layers from the basal to mucosal side. These effects were completely abolished by a mixture of a monoclonal antibody regulated on activation, normal T cells expressed and secreted (RANTES) and an antibody to granulocyte macrophage-colony stimulating factor (GM-CSF).Conclusion These results suggest that human respiratory SMG cells may augment eosinophil transmigration across the airway epithelium through the secretion of RANTES and GM-CSF after RV infection, and may contribute to exacerbations of asthma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2222.2004.1865.x
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  • 3
    Electronic Resource
    Electronic Resource
    γ-Interferon enhances expression of CD14/MyD88 and subsequent responsiveness to lipopolysaccharide from Actinobacillus actinomycetemcomitans in human gingival fibroblasts (2004)
    Oxford, UK : Munksgaard International Publishers
    Journal of periodontal research 39 (2004), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives:  CD14, toll-like receptor 4 (TLR4) and MyD88 have been shown to mediate responsiveness in host cells to lipopolysaccharide. We investigated here the regulatory effects of inflammatory cytokines on the expression of membrane CD14 (mCD14), TLR4 and MyD88, and on subsequent responsiveness to lipopolysaccharide from Actinobacillus actinomycetemcomitans in human gingival fibroblasts.Materials and methods:  Following treatment with either interleukin-1β, tumor necrosis factor-α (TNF-α) or γ-interferon (IFN-γ), expression of mCD14/TLR4 and MyD88 was determined by flow cytometry and western blotting, respectively. After pretreatment with IFN-γ, cells were pre-incubated with either anti-CD14 antibody MY4 or anti-TLR4 antibody HTA125 and subsequently treated with A. actinomycetemcomitans lipopolysaccharide. Then, phosphorylation of mitogen-activated protein (MAP) kinases and IκBα was examined by western blotting, and production of interleukin-6 and interleukin-8 was measured by their respective enzyme-linked immunosorbent assay (ELISA) kits.Results:  IFN-γ stimulated expression of mCD14, whereas -1β and TNF-α did not. Expression of MyD88 but not TLR4 was also enhanced by IFN-γ. The lipopolysaccharide activated MAP kinases, such as extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK) and p38, and IκBα and stimulated production of interleukin-6 and interleukin-8. The lipopolysaccharide-stimulated interleukin-6 and interleukin-8 production was markedly inhibited by MY4 or HTA125. Pretreatment with IFN-γ augmented the following activation of MAP kinases and IκBα and production of interleukin-6 and interleukin-8 in response to the lipopolysaccharide.Conclusions:  These results suggest that the augmentation by IFN-γ of the responsiveness to A. actinomycetemcomitans lipopolysaccharide, such as activation of MAP kinases and IκBα and terminal cytokine production in human gingival fibroblasts, may be partially mediated by up-regulation of CD14 and MyD88 expression.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.2004.00749.x
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  • 4
    Electronic Resource
    Electronic Resource
    Neutrophilic phlebitis is characteristic of intestinal Behçet's disease and simple ulcer syndrome (2004)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 45 (2004), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim : To characterize the histological features of intestinal Behçet's disease and simple ulcer syndrome and to clarify the possible mechanisms involved in their development by analysing the type of inflammatory infiltrates in the diseased intestine and the expression of adhesion molecules on endothelial cells.Methods and results : Tissue samples from 10 patients diagnosed as having intestinal Behçet's disease or simple ulcer syndrome were studied. Immunohistochemical studies were performed on paraffin-embedded tissue using a labelled streptavidin–biotin method. In all cases, phlebitis was remarkably seen in submucosal inflammatory lesions, but the adjacent arteries were not affected. Inflammatory infiltrates around the affected vessels consisted of neutrophils and mononuclear cells, and neutrophils predominated over CD68+ macrophages and lymphocytes. The majority of mononuclear cells were CD3+ T cells, and CD4+ cells were more frequent than CD8+ T cells. As for adhesion molecule expression, intercellular adhesion molecule-1, but not vascular cell adhesion molecule-1, was expressed in most endothelial cells of the vessels with phlebitis, some of which were also positive for HLA-DR.Conclusion : Neutrophilic phlebitis may be involved in the pathogenesis of intestinal Behçet's disease and simple ulcer syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2004.01954.x
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  • 5
    Electronic Resource
    Electronic Resource
    Evidence from mucin core protein expression that some Paget's disease on areola can be of extramammary-like histogenesis and part of multisite disease (2004)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 151 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Triple extramammary Paget's disease, which consists ordinarily of bilateral axillary and genital lesions, is uncommon. Triple extramammary Paget's disease involving other sites has never been reported, although solitary extramammary Paget's disease can occur at various sites around the body. Erythematous plaques on the areola, axilla and genitalia of a 91-year-old man were surgically removed under the clinical diagnosis of multiple extramammary Paget's disease. Histology revealed that all three lesions consisted of intraepidermal nests of Paget cells and other isolated Paget cells scattered in the epidermis. Although adnexal invasion was observed in the genital lesion, neither intraductal invasion nor underlying breast carcinoma was detected in the areolar lesion. Immunohistochemically, the Paget cells in all lesions expressed simple epithelial cytokeratins (CK8, 18 and 19), mucin (MUC)1 and MUC5AC, but neither CK20 nor MUC2. From the histological findings, the present case was interpreted as triple extramammary Paget's disease rather than synchronous mammary and extramammary Paget's disease. Furthermore, the mucin core protein expression pattern, which was identical to that observed in extramammary Paget's disease, supported the above interpretation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.06087.x
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  • 6
    Electronic Resource
    Electronic Resource
    Detection of human papillomavirus type 56 DNA, belonging to a mucous high-risk group, in hair follicles in the genital area of a woman no longer suffering from viral warts (2004)
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 151 (2004), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Human papillomaviruses (HPVs) parasitize human epithelium, but it is not clear where they reside when they do not cause apparent infection. Hair follicles are important candidates as reservoirs.Objectives  A patient reported previously by us as having perianal warts caused mainly by HPV 56, demonstrated hair follicles in her genital area which bulged a little from the surface and appeared somewhat enlarged. We therefore examined whether DNA of HPV 56, a member of the mucous high-risk group, might be detectable in these structures.Methods  We obtained plucked hairs and performed an examination by polymerase chain reaction and subsequent reverse-phase dot blot hybridization (PCR-RDBH) and in situ hybridization (ISH).Results  Strong positive signals were obtained not only with PCR-RDBH but also with ISH.Conclusions  Hair follicles in the genital area might serve as reservoirs for HPVs belonging to the mucous high-risk group.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.2004.05955.x
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  • 7
    Electronic Resource
    Electronic Resource
    Deformation Measurement of Wood Subjected to Shearing Loads Using Electronic Speckle Pattern Interferometry (2004)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 261-263 (Apr. 2004), p. 1659-1664 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The two-dimensional deformation of wood under shearing loads is measured using an electronic speckle pattern interferometry (ESPI) technique. The radical and tangential sections of Douglas firs are used as specimens in the longitudinal direction. Results reveal that large two-dimensional deformation of the wood can be measured using the ESPI technique, the deformation values significantly vary for every part of the specimens, and the ring directions of earlywood and latewood, which compose the annual rings, have an effect on the two-dimensional deformation of wood
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/47/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.261-263.1659.pdf
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