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  • 2005-2009
  • 2000-2004  (2)
  • 1980-1984
  • 1930-1934
  • Altimetry  (1)
  • Arthritis  (1)
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  • 2005-2009
  • 2000-2004  (2)
  • 1980-1984
  • 1930-1934
Year
  • 1
    ISSN: 1432-1459
    Keywords: Key words HLA ; Rheumatic ¶fever ; Sydenham’s chorea ; Carditis ; Arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sydenham’s chorea (SC) may occur in rheumatic fever (RF) patients without arthritis and carditis. In this study we typed HLA antigens and alleles in patients presenting with the distinct major clinical manifestations of RF, i.e., chorea, carditis, or arthritis, in population and family studies. We evaluated 91 patients with RF for HLA-A, HLA-B, and HLA-DR antigens; of these, 33 had pure chorea, 26 pure carditis, 16 pure arthritis, and 16 carditis plus arthritis. We also typed 24 SC patients and their unaffected siblings for HLA-DRB1 and HLA-DQB1 alleles using molecular methods. HLA-B49 and HLA-DR1 antigens were overrepresented in the total group of patients with RF and in all the subgroups studied, excluding the SC subgroup in which the frequency of HLA-DR1 antigen was not increased. The frequencies of the HLA-DRB1 and HLA-DQB1 alleles in patients with pure chorea were not significantly different from those observed in controls. Similarly, the frequencies of HLA class II alleles in SC patients did not differ significantly from those observed in unaffected siblings. These findings show that immunogenetic susceptibility to RF varies according to the major clinical manifestation presented by the patient.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of geodesy 74 (2000), S. 399-413 
    ISSN: 1432-1394
    Keywords: Key words: Ocean tides ; Altimetry ; T/P ; ERS-1 ; GEOSAT
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract.  Aliasing of the diurnal and semi-diurnal tides is a major problem when estimating the ocean tides from satellite altimetry. As a result of aliasing, the tides become correlated and many years of altimeter observations may be needed to seperate them. For the three major satellite altimetry missions to date i.e., GEOSAT, ERS-1, and TOPEX/POSEIDON (T/P), the alias periods as well as the Rayleigh periods over which the tides decorrelate can be identified. Especially in case of GEOSAT and ERS-1, severe correlation problems arise. However, it is shown by means of covariance analyses that the tidal phase advance differences on crossing satellite groundtracks can significantly reduce the correlations among the diurnal and semi-diurnal tides and among these tides and the seasonal cycles of ocean variability. Therefore, it has been attempted to solve a multi-satellite response tidal solution for the diurnal and semi-diurnal bands from a total of 7 years of altimetry. Unfortunately, it could be shown that the GEOSAT and ERS-1 orbit errors are too large to improve a 3-year T/P tidal solution with about 2 years of GEOSAT and 2 years of ERS-1 altimeter observations. However, these results are preliminary and it is expected that more accurate orbits, which have become available recently for ERS-1, and additional altimeter data from ERS-2 and the GEOSAT Follow-On (GFO) should lead to an improved T/P tidal model.
    Type of Medium: Electronic Resource
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