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  • 1
    Electronic Resource
    Electronic Resource
    Oblique grain boundaries: Analysis of light and electron beam induced current profiles in silicon (1988)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 63 (1988), S. 4748-4750 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Asymmetrical light and electron beam induced current profiles have been previously attributed to a difference of the diffusion length on the two sides of the grain boundary. We show that this feature is instead due to the grain boundary not being perpendicular to the surface. In this geometry, the equations describing the minority-carrier diffusion are not solvable by analytical procedures. A method for their numerical solution is hereby introduced, fast enough to allow the use of minimization procedures. A good agreement has been found between fitted values of the grain boundary inclination and those directly measured.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.340135
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  • 2
    Electronic Resource
    Electronic Resource
    Selective and High-Yield Synthesis of Higher Fullerenes (1995)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 99 (1995), S. 17785-17788 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100050a018
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  • 3
    Electronic Resource
    Electronic Resource
    Silicon carbide formation by annealing C60 films on silicon (1997)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 81 (1997), S. 6141-6146 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Silicon carbide films were grown on (100) silicon substrates by deposition of 200-nm-thick C60 films, followed by annealing. The predeposited C60 is progressively destroyed by annealing, and carbon reacts with silicon to produce SiC. The reaction starts at the interface and continues by diffusion of silicon through the already formed SiC. At the lower temperatures (700 °C), the reaction is localized at the interface. Diffusion of silicon and formation of stoichiometric SiC requires annealing at 800 °C for t≥100 min and at 900 °C for t≥25 min. The stoichiometric films are uniform with a grain size of 20–40 nm. A diffusion coefficient of silicon in SiC of 4×10−15 cm2/s at 900 °C was determined. Because the diffusion of silicon is faster through preferential paths in the SiC film, such as grain boundaries and other crystalline defects, pits and voids are produced in the silicon substrate when the C60 predeposited film covers larger areas. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.364395
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  • 4
    Electronic Resource
    Electronic Resource
    Ovarian regression and apoptosis in the South American teleost Leporinus taeniatus Lütken (Characiformes, Anostomidae) from the São Francisco Basin (2005)
    Oxford, UK; Malden, USA : Blackwell Science Ltd
    Journal of fish biology 67 (2005), S. 0 
    Details
    ISSN: 1095-8649
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Involution and resorption of both postovulatory and atretic follicles were analysed in piau-jejo Leporinus taeniatus(Characiformes, Anostomidae) in order to evaluate the role of apoptosis during ovarian regression. Histological and ultrastructural analyses showed hallmarks of apoptosis in the granulosa: aggregation of compacted chromatin against the nuclear envelope, cell shrinkage, surface blebbing, loss of cell adhesion and cell fragmentation into apoptotic bodies. Protein synthesis activity preceded the onset of the cell death. The breakdown of the basement membrane led to the detachment of the granulosa cells into the follicular lumen. TUNEL-positive reactions were detected in in situ DNA fragmentation of granulosa of both postovulatory and atretic follicles. Apoptosis increased in a time-dependent manner contributing to reduction of the follicular areas. The apoptotic index (per cent of apoptotic cells) of the granulosa increased in postovulatory follicles soon after spawning, then these follicles degenerated and only remnants were observed at 7 days. In contrast, the granulosa cells reabsorbed the yolk during follicular atresia and the apoptotic index increased only in the late stage of regression. The results indicated apoptosis as the major mechanism to rapidly eliminate postovulatory follicles and being an essential process in the ovarian regression after spawning.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1095-8649.2005.00854.x
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  • 5
    Electronic Resource
    Electronic Resource
    Islet cell and insulin autoantibodies in organ-specific autoimmune patients. Their behaviour and predictive value for the development of Type 1 (insulin-dependent) diabetes mellitus. A 10-year follow-up study (1987)
    Springer
    Diabetologia 30 (1987), S. 292-297 
    Details
    ISSN: 1432-0428
    Keywords: Type 1 (insulin-dependent) diabetes mellitus ; autoimmune diabetes ; islet cell autoantibodies ; insulin autoantibodies ; organ-specific autoimmune diseases
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To evaluate the behaviour and predictive value of islet cell and insulin autoantibodies in patients with organspecific autoimmune diseases, we followed 21 non-diabetic subjects for a mean period of 84±27 months. Ten patients were persistently seropositive for complement-fixing islet cell antibodies and high titres of immunoglobulin G islet cell antibodies (≥ 1∶8). The prevalence of persistent insulin autoantibodies in this group was 67%. Seven patients (70%) developed Type 1 (insulin-dependent) diabetes mellitus after a latency period of 2–60 months. The predictive value of complement-fixing islet cell antibodies was 65%, and in the presence of both complement-fixing islet cell and insulin autoantibodies the predictive value rose to 76%. Eleven patients were seronegative for complement-fixing islet cell antibodies and had low immunoglobulin G islet cell antibodies titres (〈 1∶8) that were either persistent or transient, or that fluctuated during follow-up. The prevalence of persistent insulin autoantibodies in this group was 45%; only one subject developed Type 1 diabetes. The predictive value of persistent islet cell antibodies (complement-fixing positive/negative) was 54%, and it rose to 70% when both islet cell and insulin autoantibodies were present. Individuals with only insulin autoantibodies or immunoglobulin G islet cell antibodies did not develop diabetes mellitus. A high frequency of HLA-DR3 and/or DR4 was found in patients who developed diabetes mellitus. Thus, the presence of both islet cell and insulin autoantibodies in patients with organ-specific autoimmune disease appears to confer the highest risk of progression toward Type 1 diabetes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00299020
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  • 6
    Electronic Resource
    Electronic Resource
    Detection of pyridinium cross-links in human bile (1995)
    Springer
    Calcified tissue international 57 (1995), S. 415-418 
    Details
    ISSN: 1432-0827
    Keywords: Pyridinium cross-links ; Bile ; Excretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract This study evaluated whether pyridinium cross-links, which are positively charged, besides renal clearance are also cleared by the liver into bile. In 13 human bile samples tested, we were able to detect both pyridinoline (PYD) and deoxypyridinoline (DPD) in small amounts which were estimated to be about 1–2% of the amount usually found in urine. To further evaluate the amount of pyridinium cross-links excreted through bile, we studied the stability of these compounds at the alkaline pH of bile. No effect on their stability was detected over a 6-hour incubation. The origin of these molecules in bile and the significance of this finding in the use of PYD and DPD as bone resorption markers are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00301942
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  • 7
    Electronic Resource
    Electronic Resource
    Collagen Type I of Rat Cortical and Trabecular Bone Differs in the Extent of Posttranslational Modifications (1996)
    Springer
    Calcified tissue international 58 (1996), S. 65-69 
    Details
    ISSN: 1432-0827
    Keywords: Key words: Collagen — Glycosylation — Trabecular — Cortical — Bone.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. This study sought to evaluate whether the architecture of the matrix of cortical and trabecular bone is exactly the same. For this purpose we analyzed the extent of some posttranslational modifications of type I collagen, which is the major component of bone matrix. Ten female and 10 male 100-day-old rats were sacrificed and the content of hydroxylysine, glycosylated hydroxylysine, and pyridinium cross-links of collagen from cortical and trabecular bone was determined. The amount of each compound was expressed as a molar ratio with hydroxyproline. The collagen posttranslational modification pattern appears to be the same in both sexes but with a higher extent of differences in females compared with males. Comparing cortical and trabecular bone, the former contains a higher amount of hydroxylysine residues whereas in the latter, glycosylation of hydroxylysine is higher and pyridinium cross-link concentration is lower. Moreover, an inverse linear relationship between glycosylated hydroxylysine and pyridinium cross-links concentration was established, both for female (r =−0.455, P= 0.04) and male rats (r =−0.426; P= 0.06). This paper discusses what these findings may mean in functional terms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002239900012
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