ISSN:
1432-0800
Source:
Springer Online Journal Archives 1860-2000
Topics:
Energy, Environment Protection, Nuclear Power Engineering
,
Medicine
Notes:
Summary Rats submitted to p,p′-DDT at 200 ppm in drinking water showed increased p, p′-DDT storage which was not statistically different from that of thyroidectomized rats receiving p, p′-DDT. Rats receiving p, p′-DDT also showed increased fat storage of total o, p′-DDT and Dieldrin and decreased total BHC storage. Thyroidectomy decreased the amount of p, p′-DDT naturally occurring in the animal body and raised the metabolization of this compound. In thyroidectomized rats submitted to the same dosage of p, p′-DDT, increased storage of p, p′-DDT, o, p′-DDT and Dieldrin was found. A statistically significant increase in BHC was also observed. It is concluded that p, p′-DDT in the diet may affect the storage level of other organochlorine insecticides depending on its concentration, and that the physiopathological state of the body, e. g. thyroidectomy has a definite influence on the storage of organochlorine insecticides in the animal body and on their biological effect.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01560963
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