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  • 2005-2009  (3)
  • 1995-1999  (6)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK and Boston, USA : Blackwell Publishers Ltd
    R & D management 27 (1997), S. 0 
    ISSN: 1467-9310
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: Despite the importance of the early stages of a product's life, very little attention has been paid to empirically testing the activities performed in the front end of new product development. This article presents the results of a survey of 53 individuals from fifteen high technology firms in the integrated circuit board industry. Our study adopts Cooper's (1988) ‘predevelopment’ model consisting of idea generation, product definition and project evaluation stages, and probes the activities undertaken in each stage. Particular activities were found to play pivotal roles in achieving the objectives of each stage. The results present a clarified view of front end activities that can be used as a starting point for adequately preparing products for development and market success.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Team performance management 11 (2005), S. 263-279 
    ISSN: 1352-7592
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Purpose - This article is the first in a two-part discussion of the determinants and performance consequences of concurrent engineering (CE) team usage in organizations. The purpose of this first article is to develop a model of the organizational factors that influence the extent that CE teams are used when developing new products. Design/methodology/approach - To test the model, 2,500 questionnaires were mailed to new product development (NPD) managers from the machinery, computer product, electrical equipment, and transportation equipment manufacturing industries, of which 189 usable questionnaires were returned, for a usable response rate of 7.5 percent. The data were analyzed using structural equation modeling with partial least squares. Findings - Results indicate that an innovative organizational climate and complex NPD activities both influence the extent that organizations support functional integration on NPD teams, and this support, in turn, influences the extent that organizations use CE teams. Analyzing the qualitative data using content analysis indicates additional factors influencing CE team usage. Research limitations/implications - To researchers, this study examines in detail the extent of CE team usage, thus addressing a major gap in the research literature. This study also addresses the concerns of researchers by examining organizational contextual factors. Practical implications - To NPD managers, this study highlights organizational precursor conditions needed in order for CE teams to be supported in the organizations, specifically complex NPD activities and an innovative organizational climate. By examining these two variables, NPD managers can gauge the likelihood that CE teams will be supported even before they are actually implemented.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Team performance management 11 (2005), S. 27-39 
    ISSN: 1352-7592
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Economics
    Notes: Purpose - This research aims to identify various organizational-level factors influencing support for cross-functional new product development (NPD) teams. Design/methodology/approach - A total of 2,500 questionnaires where mailed in 2003 to managers of product development from Canadian and US manufacturing organizations operating in the machinery, computer, electronic product, electrical equipment, and transportation equipment manufacturing industrial sectors. A total of 269 usable questionnaires were returned for a response rate of 11.1 percent. Findings - Results of performing regression analysis indicate that the quality of communication between the functional disciplines involved in NPD activities, perceived risks and complexity of using cross-functional NPD teams, and the complexity of the organization's NPD activities all influence organizational support for cross-functional NPD teams. Based on the qualitative data, additional reasons why cross-functional NPD teams may not be supported in organizations are identified and discussed. Research limitations/implications - The major limitation of this study is that the respondents are NPD managers. These managers commented on the extent that support for cross-functional NPD teams exists at the team, departmental, and senior management levels. Future research should focus on gauging organizational support for cross-functional NPD teams by directly surveying team members, functional managers, and senior managers. Practical implications - This study identifies various organizational-level factors influencing support for cross-functional NPD teams. Originality/value - This research is of value to managers using or implementing cross-functional teams, as it indicates potential organizational-level factors that may facilitate or hamper the usage of such teams. To researchers, it provides a starting point in studying the determinants of support for cross-functional NPD teams, and cross-functional teams in general.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature genetics 39 (2007), S. 1309-1310 
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Being rooted to the spot, plants are vulnerable to changes in their environments. Temperature in particular is quite challenging and can easily fluctuate within a 40 °C range in temperate climates. Although plants are largely unable to modulate their core temperature, they are far from passive ...
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1433-8726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature America Inc.
    Nature structural biology 6 (1999), S. 80-88 
    ISSN: 1072-8368
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] The crystal structure of calcium-bound unmyristoylated bovine neurocalcin from Escherichia coli has been determined at 2.4 Å resolution. The three-dimensional structure reveals a highly compact structure consisting of: (i) two pairs of calcium-binding EF-hands (EF1-EF2 and EF3-EF4); (ii) a ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Transition metal chemistry 24 (1999), S. 463-466 
    ISSN: 1572-901X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The bidentate ligands, 2-[(N-acetyl)aminopyridine] (AAPH, A) and 2-[(N-benzoyl)aminopyridine] (BAPH, B) have been used to synthesize copper(II) complexes including an exogenous ligand X (X = AcO−, HCO2 −, N3 − and benzimidazole). The complexes were characterized by elemental analysis, electronic and vibrational spectroscopy, magnetic and e.s.r. studies. E.s.r. parameters and visible spectra indicated that all the complexes are monomers and exist in distorted octahedral geometry except for benzimidazole. With benzimidazole as an exogenous ligand, a five coordinate complex is formed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    The journal of technology transfer 24 (1999), S. 81-96 
    ISSN: 1573-7047
    Source: Springer Online Journal Archives 1860-2000
    Topics: Technology
    Notes: Abstract This research investigates the critical elements affecting the ability of firms in developing countries to cultivate their technological capability through imported technology. The information obtained from forty-five technology recipient Indonesian manufacturing firms indicate that the cultivation of technological capability is affected by several factors such as a firm's technological absorption capacity in terms of R&D activities and availability of technical personnel; transfer channels; government's involvement; and a firm's learning culture. Also, the acquisition of mature technology just to boost production capacity or improve product quality contributes very little to the development of technological capability.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Proteins: Structure, Function, and Genetics 25 (1996), S. 261-264 
    ISSN: 0887-3585
    Keywords: X-ray diffraction ; calcium-binding myristoylation ; noncrystallographic symmetry ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Neurocalcins are novel brain-specific proteins that belong to a new subclass of the EF-hand super-family of calcium binding proteins, defined by the photoreceptor cell-specific protein recoverin (Terasawa et al., J. Biol. Chem. 267:19596-19599, 1992). Here we report the purification and crystallization of unmyristoylated recombinant bovine neurocalcin δ from Escherichia coli. Crystals of a bovine neurocalcin δ have been grown by macro-seeding at room temperature through vapor phase equilibration using the hanging drop technique with ammonium sulfate as the precipitating agent. The crystals diffract to at least 2.5 Å resolution and belong to monoclinic space group P2I with unit cell dimensions a = 42.734 Å, b = 94.343 Å, c = 50.696 Å, and β = 98.37°. The asymmetric unit contains two molecules, with corresponding crystal volume per protein mass (Vm) of 2.29 Å3/Da and solvent fraction of 45% by volume, exhibiting an approximate 222 point symmetry. © 1996 Wiley-Liss, Inc.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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