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  • 1
    Electronic Resource
    Electronic Resource
    A randomised controlled trial of a new handheld vacuum extraction device (2005)
    Oxford, UK and Malden, USA : Blackwell Science Ltd
    BJOG 112 (2005), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective  To evaluate the effectiveness of a new handheld vacuum delivery device.Design  Randomised controlled trial.Setting  Southmead Hospital, Bristol, UK.Population  One hundred and ninety-four women requiring delivery with vacuum extraction.Methods  Women were recruited into the study while still in early labour. If during delivery, vacuum extraction was indicated they were then randomly allocated to either a new handheld vacuum device, the Kiwi Omnicup, or to a ‘standard’ vacuum cup selected by the obstetrician. The ‘standard group’ consisted of the silastic (66/98, 67%) or the metal cups (32/98, 33%). Study data were recorded at completion of the delivery and at 24–48 hours. An additional brief symptom questionnaire was completed by the mother at 10 days postnatally. Statistical analyses were done on an ‘intention-to-treat’ basis.Main outcome measures  The primary outcome was the successful completion of delivery with the allocated instrument. Secondary outcomes were substantial fetal scalp trauma and substantial maternal trauma.Results  The Omnicup was associated with a significantly higher failure rate than the standard cup [34%vs 21%, odds ratio (OR) = 1.9 (1.01–3.6)]. This difference persisted after adjusting for confounding factors [adjusted OR = 2.25 (1.01–5.0)] and resulted in significantly more forceps deliveries in the Kiwi Omnicup group [22%vs 10%, unadjusted OR = 2.5 (1.1–5.5)]. The caesarean section rates were similar in both groups [9.4%vs 8.2%, OR = 1.2 (0.4–3.2)]. Rates of substantial scalp trauma and maternal trauma were similar in both groups. However, there were more cases of jaundice in the standard cup group [2.3%vs 12.0%, unadjusted OR = 0.18 (0.04–0.82) and adjusted OR = 0.10 (0.01–0.88)].Conclusions  The Omnicup is not as successful at achieving a vaginal delivery as the combination of the currently used vacuum cups.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2005.00729.x
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  • 2
    Electronic Resource
    Electronic Resource
    Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: Results of a pilot study (1997)
    Springer
    Inflammation research 46 (1997), S. 420-422 
    Details
    ISSN: 1420-908X
    Keywords: Key words: Dapsone metabolites — LTB4— Polymorphonuclear leukocytes — Skin — Chemotaxis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Objective: Dapsone (4,4'diaminodiphenylsulfone) is effective in treating leprosy, chronic inflammatory conditions and opportunistic infections in HIV patients. By the oral route, the sulfone is metabolized to monoacetyldapsone (MADDS) and dapsone hydroxylamine (DDS-NOH). We have addressed the question as to whether these dapsone metabolites have anti-inflammatory properties of their own in vivo.¶Treatment and Methods: After two weeks topical pre-treatment with MADDS (1%), DDS-NOH (1%) and clobetasol proprionate (CP; 0.05%) dissolved in acetone, as a reference, 10 ng leukotriene B4 (LTB4) were applied on the upper arms of eight healthy volunteers. After 24 h, biopsies were taken and the polymorphonuclear leukocytes (PMN) were quantified fluorometrically using elastase as marker enzyme.¶Results: MADDS did not show any inhibitory activity on trafficking of PMN compared to the corresponding control and nontreated area (untreated: 790 ± 450 PMN/10 μg skin; p 〉 0.05, acetone: 840 〉 578 PMN/10 μg skin; MADDS: 1099 〉 556 PMN/10 μg skin), whereas DDS-NOH caused a statistically significant inhibition of PMN accumulation as did the reference CP (DDS-NOH: 128 〉 143 PMN/10 μg skin; CP: 86 〉 131 PMN/10 μg skin, p 〈 0.01).¶Conclusions: These results indicate that DDS-NOH has anti-inflammatory potential which might contribute to the effectiveness of dapsone therapy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s000110050215
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  • 3
    Electronic Resource
    Electronic Resource
    Lieblingsspeisen und Einflüsse auf die Nahrungspräferenzen von Kindergartenkindern (1996)
    Springer
    European journal of nutrition 35 (1996), S. 143-149 
    Details
    ISSN: 1436-6215
    Keywords: Nahrungspräferenzen ; Verzehrsgewohnheiten ; Lieblingsspeisen ; Ernährungserziehung ; sozial-kulturell ; Food preferences ; eating habits ; favorite foods ; nutritional education ; sociocultural data
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary This study was conducted by the Technical University of Munich-Weihenstephan on behalf of the Department of Education of the city of Munich. A total of 82 children as well as their parents and 23 kindergarten teachers in five Munich kindergartens were questioned about their food preferences, and their sociocultural data were gathered. The results showed that the nationality and the religion of the mother were fundamental to the origin and consolidation of the eating habits of the children. Other important und influencing factors were: the peer group and the teachers in the kindergarten, the father's job, the sex and the age of the children. When comparing the food preferences of the children and their role models, it was found that the preferences and aversions were more similar to those of their own mothers/teachers/members of the peer group than to those of children of other peer groups, other parents or other teachers.
    Notes: Zusammenfassung Im Auftrag des Schulreferats der Stadt München wurden an der Technischen Universität München-Weihenstephan insgesamt 83 Kinder sowie deren Eltern und 23 Erzieherinnen in 5 Münchner Kindergärten zu ihren Nahrungspräferenzen befragt und ihre sozial-kulturellen Einflüsse untersucht. Die Ergebnisse zeigten, daß die Staatsangehörigkeit und Religion der Mutter wesentlich zur Entstehung und Festigung der Verzehrsgewohnheiten von Kindern beitragen. Als weitere wichtige Einflußfaktoren erwiesen sich die Kindergartengruppe, der Beruf des Vaters, das Geschlecht und das Alter der Kinder. Beim Vergleich der Nahrungspräferenzen von Kindern und ihren Bezugspersonen zeigte sich, daß die Vorlieben und Abneigungen von Kindern und ihren eigenen Müttern/Erzieherinnen/Gruppenkameraden ähnlicher waren als die von Kindern und Müttern/Erzieherinnen/Gruppenkameraden anderer Kindergartenkinder. Daraus wird der Schluß gezogen, daß die eigene Mutter und Bezugspersonen einen hohen Einfluß bei der Ausprägung von Nahrungspräferenzen haben.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01622862
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