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  • 2005-2009
  • 1985-1989  (1)
  • 1970-1974  (1)
  • Clinical Response  (1)
  • Pinus resinosa  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The possible role of metabolites in therapeutic response to chlorpromazine treatment (1973)
    Springer
    Psychopharmacology 32 (1973), S. 279-284 
    Details
    ISSN: 1432-2072
    Keywords: Chlorpromazine ; 7-Hydroxychlorpromazine ; Chlorpromazine Sulphoxide ; Clinical Response
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Eight male adult schizophrenic patients undergoing chronic treatment with chlorpromazine were investigated. Clinical assessments were made weekly by a psychiatrist who was unaware of the biochemical findings. Blood samples were drawn 3 h after the first daily dose and the plasma concentrations of chlorpromazine and 11 of its metabolites were assessed by a direct scan technique employing quantitative thin layer chromatography. Patients that responded well to treatment had high plasma levels of chlorpromazine and 7-hydroxychlorpromazine; whereas non-responders had high plasma levels of chlorpromazine sulphoxide. These preliminary findings support the hypothesis that chlorpromazine metabolites play an important role in determining clinical response to treatment, which arose from the failure of previous investigators to show a statistically significant relationship between plasma levels of the parent compound and clinical response.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422150
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cross-attraction between two species ofMatsucoccus (1986)
    Springer
    Journal of chemical ecology 12 (1986), S. 609-617 
    Details
    ISSN: 1573-1561
    Keywords: Sex pheromone ; interspecific attraction ; red pine scale ; Matsucoccus resinosae ; Matsucoccus n. sp. ; Pinus resinosa ; Pinus thunbergiana ; Homoptera ; Coccoidea ; Margarodidae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract In laboratory bioassays, males ofMatsucoccus resinosae fromPinus resinosa in New York andMatsucoccus n. sp. fromPinus thunbergiana in Korea were strongly attracted to crude hexane extracts ofM. resinosae females, andM. resinosae males responded strongly to extracts ofMatsucoccus n. sp. females. Males of the two species responded similarly to gas chromatographic fractions and subfractions of a pentane extract ofM. resinosae females. Sex pheromones of these two species appear to be the same or very similar.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01012096
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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