ISSN:
1432-2072
Keywords:
Morphine
;
Self-stimulation
;
Response dependency
;
Lateral hypothalamus
;
Rats
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The effects of morphine (10mg/kg) on intracranial self-stimulation were studied in three separate test situations, each requiring rats to perform different types of responses. Self-stimulation was depressed in a test of rate of bar-pressing, to a lesser extent in a test of rate of wall-pressing in which a wider range of movements were reinforced, but not in a shuttle-box, with brain stimulation continuously available on one side of box. This response dependency suggests that the depressive effect of morphine on bar-pressing for lateral hypothalamic stimulation reflects a performance deficit rather than an effect on the reinforcing value of the stimulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00426791
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