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Cystic fibrosis: Normal volumes of red cells (1976)

Emrich, H. M. ; Heitz, J. ; Katz, S. ; [et al.]

Springer

European journal of pediatrics 122 (1976), S. 293-296

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ISSN: 1432-1076

Keywords: Cystic fibrosis ; Red cells ; Salt-transport defect ; Valinomycin ; Gramicidin D

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Description / Table of Contents: Zusammenfassung Das mittlere Zellvolumen (MCV) und der Volumen-Variationskoeffizient von Erythrocyten wurde mit Hilfe eines elektronischen Partikel-Volumen-Analysators (Zentralstrahlcapillare) bei Patienten mit Mucoviscidose (cystische Pankreasfibrose (C.F.)) und gesunden Kontrollen gemessen. Da die Meßwerte bei C.F. nicht signifikant von den Normalwerten abweichen, wird ein ausgeprägter Defekt des Salztransportes bei C. F.-Erythrocyten als unwahrscheinlich angesehen. Nach Zusatz von Valinomycin zu Normalerythrocyten wird eine Volumenabnahme (durch Steigerung der K+-Permeabilität), nach Zusatz von Gramicidin D eine Volumenzunahme (durch Steigerung der Na+-Permeabilität) beobachtet. Zugabe von C.F.-Schweiß zu Normalerythrocyten bewirkt keine Volumenänderung. Hieraus wird geschlossen, daß der „C.F.-Faktor” keinen Einfluß auf die passive Ionenpermeabilität der Erythrocytenmembran hat.

Notes: Abstract Normal values of mean cell volume (M.C.V.) and of distribution of single cell volumes (S.C.V.) have been observed in erythrocytes of patients with cystic fibrosis using an electronical particle-volume analyzer (sheath flow detector). From these results a strong defect in red cell salt transport seems improbable. Valinomycin induces shrinking (by increase of K+ permeability) and gramicidin D induces swelling (by increase of Na+ permeability) of normal erythrocytes. Addition of C.F. sweat to normal erythrocytes induces no volume change. From this result no influence of the “C.F. factor” on passive ion permeability is concluded.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00481510

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F〈sub〉2〈/sub〉-Laser Angle Nanomodification of PET (2007)

Slepička, Petr ; Heitz, J. ; Siegel, Jakub ; [et al.]

s.l. ; Stafa-Zurich, Switzerland

Materials science forum Vol. 567-568 (Dec. 2007), p. 257-260

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ISSN: 1662-9752

Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008

Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics

Notes: This work is focused on laser modification of polymers with different angles ofincidence. Periodic surface structures generated by linearly polarized F2 laser light (157 nm) onpolyethyleneterephthalate (PET) were studied. Atomic force microscopy was used to study thetopological changes induced by the laser irradiation. The laser irradiation induces the formation ofperiodic ripple structures, the width of and the height being angle dependent. The periodic structureswere formed with the laser fluence 4.70 mJ/cm2. The laser modified PET foils were coated with a50 nm thick gold layer by sputtering. After Au deposition on the laser PET foils with ripplestructure, the roughness of surface decreases in comparison to PET with ripples without Au coating