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  • 2005-2009  (38)
  • 1
    Electronic Resource
    Electronic Resource
    Erdheim-Chester Disease of the Breast: A Case Report and Review of the Literature (2005)
    Oxford, UK : Blackwell Publishing Ltd
    The @breast journal 11 (2005), S. 0 
    Details
    ISSN: 1524-4741
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract:  Erdheim-Chester disease (ECD) is a rare xanthomatous non-Langerhans cell histiocytosis which involves the marrow space of the long bones. Extraosseous sites most commonly affected include the eyes, lungs, pituitary glands, and kidneys. We report the case of a 49-year-old woman who presented with palpable breast nodules, followed by progressive soft tissue and subcutaneous disease, and involvement of the long bones, dysarthria, and dysphagia. The histopathologic features and skeletal radiography findings are consistent with ECD. This case represents an unusual presentation, which led to delayed diagnosis, as ECD of the breast has been rarely reported. ECD should be considered in the differential diagnosis of histiocytoid breast lesions, including fat necrosis and histiocytoid invasive mammary carcinoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1075-122X.2005.00133.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    The Impact of a Three-Tier Formulary on Demand Response for Prescription Drugs (2005)
    350 Main Street , Malden , MA 02148 , USA , and PO Box 1354, 9600 Garsington Road , Oxford OX4 2XG , UK . : Blackwell Publishing, Inc.
    Journal of economics & management strategy 14 (2005), S. 0 
    Details
    ISSN: 1530-9134
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: A large number of health plans and employers have adopted three-tier prescription drug formularies in an effort to control rising prescription drug costs. We assessed the behavioral response to three-tier adoption by estimating econometric models of the probability of selecting drugs assigned to the third tier with the highest co-payment requirement and changes in expected out-of-pocket (OOP) spending. We concluded that implementation of the three-tier formulary resulted in some shifting of costs from the plan to enrollees and some bargaining power gained for the payer, with plan savings from manufacturer rebates a likely result.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1530-9134.2005.00080.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    MODELING THE DISTRIBUTION OF DIFFUSE NITROGEN SOURCES AND SINKS IN THE NEUSE RIVER BASIN OF NORTH CAROLINA, USA (2005)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 41 (2005), S. 0 
    Details
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: This study quantified nonpoint source nitrogen (NPS-N) sources and sinks across the 14,582 km2 Neuse River Basin (NRB) located in North Carolina, to provide tabular data summaries and graphic overlay products to support the development of management approaches to best achieve established N reduction goals. First, a remote sensor derived, land cover classification was performed to support modeling needs. Modeling efforts included the development of a mass balance model to quantify potential N sources and sinks, followed by a precipitation event driven hydrologic model to effectively transport excess N across the landscape to individual stream reaches to support subsequent labeling of transported N values corresponding to source origin. Results indicated that agricultural land contributed 55 percent of the total annual NPS-N loadings, followed by forested land at 23 percent (background), and urban areas at 21 percent. Average annual N source contributions were quantified for agricultural (1.4 kg/ha), urban (1.2 kg/ha), and forested cover types (0.5 kg/ha). Nonpoint source-N contributions were greatest during the winter (40 percent), followed by spring (32 percent), summer (28 percent), and fall (0.3 percent). Seasonal total N loadings shifted from urban dominated and forest dominated sources during the winter, to agricultural sources in the spring and summer. A quantitative assessment of the significant NRB land use activities indicated that high (greater than 70 percent impervious) and medium (greater than 35 percent impervious) density urban development were the greatest contributors of NPS-N on a unit area basis (1.9 and 1.6 kg/ha/yr, respectively), followed by row crops and pasture/hay cover types (1.4 kg/ha/yr).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1752-1688.2005.tb03789.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Enhancing Homeland Security: Development of a Course on Critical Infrastructure Systems (2006)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Journal of homeland security and emergency management 3 (2006), S. 4 
    Details
    ISSN: 1547-7355
    Source: Berkeley Electronic Press Academic Journals
    Topics: Political Science , Sociology
    Notes: The rise of the American homeland security endeavor has created demands for knowledgeable professionals to address issues of critical infrastructure assurance. James Madison University has recently developed a survey course on infrastructure performance using a complex systems approach. Course development was facilitated by the enthusiastic support and participation of a multi-disciplinary faculty team. The course is designed for a broad student audience including physical science, public administration, health, business, economics and sociology majors. The course has been successful in terms of graduate and undergraduate student enrollment and has generated positive student feedback.Drawing on recent work from the physical, engineering, and social sciences, we take an interdisciplinary approach to understanding complex system operation and failure. We begin by considering historical examples of major system failures. We then explore the components, operation, and complex interdependencies of the infrastructures most critical to society. We divide critical infrastructures into three classes - commodity, service, and information - and focus on the electric power, health services and telecommunication sectors as representative examples. Students are exposed to literatures that inform their understanding of large, complex, and risky technical systems. Course material illustrates how complex systems engender unexpected interactions of failures to occur that can result in a cascade of increasingly serious disturbances often culminating in disaster. A major component of the course is devoted to defining and measuring risk. The final instruction block is devoted to risk management strategies involving both technology and public policy. The course concludes with the presentation of student projects that may address a historical complex system failure case study, an assessment of an existing infrastructure system, or survey a specific topic on complex system operation and failure.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/jhsem/vol3/iss4/4
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Targeting Corporate Political Strategy: Theory and Evidence from the U.S. Accounting Industry (2007)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Business and politics 9.2007, 2, art1 
    Details
    ISSN: 1369-5258
    Source: Berkeley Electronic Press Academic Journals
    Topics: Political Science , Economics
    Notes: By analyzing the interaction between a business firm and multiple government institutions (including a regulatory agency, an executive and a bicameral legislature), we develop predictions about how firms target their political strategies at different branches of government when seeking more favorable public policies. The core of our argument is that firms will target their resources at the institution that is 'pivotal' in the policy-making process. We develop a simple framework, drawing on the political science literature, which identifies pivotal institutions in different types of political environments. We find empirical support for our thesis in an analysis of how U.S. accounting firms shifted their political campaign contributions between the House and Senate in response to the threat of new regulations governing auditor independence during the 1990s.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/bap/vol9/iss2/art1
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Educating the Future eHealth Professional Nurse (2006)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    International journal of nursing education scholarship 3.2006, 1, art13 
    Details
    ISSN: 1548-923X
    Source: Berkeley Electronic Press Academic Journals
    Topics: Medicine
    Notes: Nursing is at the cusp of a truly revolutionary time in its history with the emergence of electronic health (eHealth) technologies to support client care. However, technology itself will not transform healthcare without skilled practitioners who have the informatics background to practice in this new paradigm of client care. Nurse educators have been slow to react to the matter of the necessary knowledge, skills, and practice competencies required for nurses to function as eHealth practitioners. Specifically, undergraduate nursing education must take a proactive stance towards curriculum development in the areas of eHealth and informatics. The purpose of this paper, therefore, is to propose recommendations about the review and redesign of nursing curricula in relation to nursing informatics. Recommendations include increased information literacy education, interdisciplinary collaboration, and client-centred technologies. Recommendations for faculty development in nursing informatics are also provided.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/ijnes/vol3/iss1/art13
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Real Output in Mental Health Care during the 1990s (2006)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Forum for health economics & policy 9 (2006), S. 5 
    Details
    ISSN: 1558-9544
    Source: Berkeley Electronic Press Academic Journals
    Topics: Medicine , Economics
    Notes: Health accounts document changes over time in the level and composition of health spending. There has been a continued evolution in the ability to track such outlays. Less rapid has been the ability to interpret changes in spending. In this paper we apply quality adjusted price indexes for several major mental disorders to national mental health expenditure account estimates to assess changes in real "output". We show that using the new price indexes reveals large gains in real output relative to the application of the U.S. Bureau of Labor Statistics' indexes.
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/fhep/9/1/5
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Comments on Richard Zeckhauser's Investing in the Unknown and Unknowable (2006)
    Berkeley, Calif. : Berkeley Electronic Press (now: De Gruyter)
    Capitalism and society 1.2006, 2, art8 
    Details
    ISSN: 1932-0213
    Source: Berkeley Electronic Press Academic Journals
    Topics: Economics
    Type of Medium: Electronic Resource
    URL: http://www.bepress.com/cas/vol1/iss2/art8
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Combining a regional climate model with a phytoplankton community model to predict future changes in phytoplankton in lakes (2005)
    Oxford, UK : Blackwell Science Ltd
    Freshwater biology 50 (2005), S. 0 
    Details
    ISSN: 1365-2427
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: 1. Linking a regional climate model (RCM) configured for contemporary atmospheric greenhouse gas concentrations, with a phytoplankton community model (PROTECH) produced realistic simulations of 20 years of recent phytoplankton data from Bassenthwaite Lake, in the North-West of England.2. Meteorological drivers were derived from the RCM to represent a future climate scenario involving a 1% per annum compound increase in atmospheric CO2 concentrations until 2100. Using these drivers, PROTECH was run for another 20 year period representing the last two decades of the 21st century.3. Comparison of these present and future simulations revealed likely impacts on the current seasonal phytoplankton development. Under future climate conditions, the simulated spring bloom showed an increase in cyanobacteria dominance caused by greater success of Planktothrix. Also, the summer cyanobacteria bloom declined earlier because of nutrient limitation caused by the increased spring growth. Overall productivity in the lake did not change.4. Analysis showed that these predicted changes were driven by changes in water temperature, which were in turn triggered by the higher air temperatures predicted by the RCM.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2427.2005.01409.x
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Spatial learning with unilateral and bilateral hippocampal networks (2005)
    Oxford, UK : Blackwell Science Ltd
    European journal of neuroscience 22 (2005), S. 0 
    Details
    ISSN: 1460-9568
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This study investigated the ability of animals to learn both reference memory and delayed matching-to-place variants of the watermaze after large lesions of the hippocampus that deliberately spared only small remnants of the structure. Groups were created that had differing blocks of residual tissue in the septal pole of the hippocampus (15% or 30% of total volume), located either unilaterally (30 or 50% on one side, 0% on the other) or bilaterally (30 + 30%). These groups were capable of learning the reference memory task, as indexed by normal spatially focused searching in a probe trial, but their rate of learning was slower than that of sham-lesioned rats. An impairment in the rate of learning was also seen in the delayed match–to-place task, where one-trial memory was observed only at the shortest (5 s) intertrial interval in the lesioned groups with the largest sparing. In both tasks performance was proportional to the volume of hippocampus spared and independent of whether this was unilaterally or bilaterally located. The findings are compatible with distributed processing accounts of hippocampal memory storage.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-9568.2005.04255.x
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