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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 68 (1996), S. 2538-2540 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: It is demonstrated that focused-ion-beam written in-plane-gate transistors, working at room temperature can be realized on (100) silicon-on-insulator wafers, separated by implanted oxygen, without the need for epitaxial growth processes. Typical channel widths are in the sub-μm range. Their electrical features at room temperature are characterized by transport and Hall measurements. The channel current is measured as a function of the geometrical channel width and the implanted dose. Activation of the implanted gallium by rapid thermal annealing changes the character of the insulating lines from Ohmic barriers to npn-junctions. Consequently the leakage current across the barriers decreases significantly, the direct current output characteristics of the transistors are improved with higher implantation doses and smaller geometrical channel widths are achievable. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Industrial & engineering chemistry research 28 (1989), S. 174-178 
    ISSN: 1520-5045
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 13 (1986), S. 0 
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Ultraviolet tight (UV)-induced tumours in mice are often highly immunogenic and have unique (individually specific) antigens which cause tumour rejection in normal mice. The molecular nature of these unique ‘rejection’ or ‘transplantation’ antigens is not known. We have recently isolated a syngeneic monoclonal antibody (mAb), CP28, that recognizes a unique tumour-specific antigen on the UV-induced regressor tumour 1591-RE. Further analysis revealed that the antibody-recognized antigen represents a novel major histocompatibility complex (MHC) class I molecule. However, the relationship of this molecule to the unique T cell-recognized antigen that causes tumour rejection remained unresolved. In this study we have explored the relationship of the antibody-defined tumour-specific novel class I molecule to the rejection antigen, that we have previously defined with a cytolytic T cell (CTL) clone (‘anti-A’). Two different lines of evidence suggested a close relationship. First, it was found that random subclones of the 1591-RE tumour expressed different levels of the CP28-defined antigen which correlated with the level of lysis by the anti-A CTL clone. Second, the selection of antigen-loss variants using either the anti-A CTL clone or the mAb CP28 resulted in the simultaneous loss of both the CP28 as well as the ‘A’ antigen. This tight correlation strongly suggests a relationship between the antibody-defined and the T cell-defined antigen. However, the role of the antibody-recognized antigen in causing transplantation rejection still needs to be determined.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 104 (1996), S. 7239-7248 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The supposedly very simple system of a saturated solution of ZnBr2 in water exhibits unusually complex and therefore interesting structural behavior. Motivated by this, Mager did a detailed x-ray diffraction study (Th. Mager, PhD. thesis, Universität Würzburg, 1991), and we performed a long molecular dynamics (MD) simulation—using potential parameters from the general purpose GROMOS force field—of such a solution, which can be grossly characterized by the formula ZnBr2⋅3H2O. We start by calculating those properties that are directly accessible through the experiment from the MD simulation, in order to validate the physical relevance of the simulation. Seeing that the simulation delivers results that are compatible with those of the experiment, we proceed by analyzing the MD simulation in much more detail according to the static and dynamic structure of the system, thereby gaining insight into the structural behavior of ZnBr2⋅3H2O that is very difficult, if at all possible, to get from experimental studies. To this end we use the Voronoi algorithm to define coordination shells around atoms and ions in ZnBr2⋅3H2O. We study the time averaged as well as the time-resolved geometry and composition of these coordination shells and find that octahedral coordination of Zn2+ ions is the dominant geometry in ZnBr2⋅3H2O, and that these octahedra are remarkably stable (after 1 ns only 10% decayed). We further find evidence for polymerlike Zn2+ chains, where O atoms of water and Br− ions connect the Zn2+ ions. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Immunology 6 (1988), S. 465-483 
    ISSN: 0732-0582
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The C3H UV-induced fibrosarcoma, 1591, is highly immunogenic and, therefore, is readily rejected when transplanted into immunocompetent syngeneic recipients. Previous analysis of 1591 with tumour-specific or H-2-reactive monoclonal antibodies revealed that this antigenicity might be due to the expression of two novel class I major histocompatibility complex (MHC) antigens. In this report we describe the molecular cloning and initial characterization of three genes which account for all of the unique serological class I reactivities observed on this tumour. These include two distinct, but highly conserved, H-2L-like genes, and a third gene the product of which bears determinants which are characteristic of both the tumour and of class I products of the H-2k haplotype. Moreover, each of these genes contains a polymorphic restriction enzyme fragment which is detected in the class I sequences of 1591 relative to normal C3H tissue. Since the expression of these polymorphic class I sequences is relevant to the immunogenicity of 1591, the mutational events by which these genes were generated may be significant to the immunobiology of this tumour.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz 43 (2000), S. 323-327 
    ISSN: 1437-1588
    Keywords: Schlüsselwörter Umwelt und Gesundheit ; Aktionsprogramm ; Umweltmedizin ; Risikomanagement gesundheitsbezogene Umweltqualitätsziele ; Keywords Environment and Health ; Action Programme ; Environmental Medicine ; Risk Management ; Health Related Environmental Quality Objectives
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract In fulfilling the commitment to the European Conferences on Environmental Health the Federal Ministry for Health and the Federal Ministry for the Environment, Nature Conservation and Nuclear Safety presented a joint “Action Programme on Environment and Health”. The action programme is backed up by a comprehensive documentation presenting the current status and findings and providing justification for the proposed goals and measures. The programme covers the following subjects: environment health monitoring and reporting, information management, risk perception and risk acceptance, environmental medicine, measures to improve co-operation among competent national authorities, international co-operation. The programme also conveys media- and substance-oriented quality objectives, in particular concerning outdoor air and climate; indoor air; water resources, soil, food; ionising radiation; noise; substances and preparations. The programme is aimed at supporting the policy development in the field of environment and health. The planing of detailed steps and the programme's implementation will be performed in close co-ordination and co-operation of all parties interested/involved and afflicted/affected.
    Notes: Zusammenfassung Das gemeinsame Aktionsprogramm “Umwelt und Gesundheit” des Ministeriums für Gesundheit und des Ministeriums für Umwelt, Naturschutz und Reaktorsicherheit löst die eingegangene Verpflichtung ein, die aus den europäischen Umweltkonferenzen resultiert. Das Programm dient dem Ziel, eine Handlungsbasis aufzustellen, auf welcher der Gesundheitszustand der Bürger und Bürgerinnen in Bereichen sichergestellt wird, die durch ungünstige Einflüsse von Umweltnoxen physikalischer Natur, mediengetragenen Umweltnoxen oder durch Aufnahme beim Umgang mit Verbraucherprodukten des täglichen Bedarfs oder durch die Nahrung gefährdet sein können. Das Programm wurde auf dem Hintergrund eines ausführlichen Dokumentationsbandes erstellt, der den aktuellen Sach- und Erkenntnisstand ausführlich darstellt und damit die vorgeschlagenen Ziele und Maßnahmen inhaltlich begründet. Das Programm enthält folgende Themen: umweltbezogene Gesundheitsbeobachtung und -berichterstattung, Informationsmanagement, Umgang mit Risiken, Umweltmedizin, Verbesserung der bestehenden Behördenstrukturen und internationale Zusammenarbeit. Das Programm enthält zudem verschiedene medien- und stoffbezogene Qualitätsziele zu folgenden Themen: Außenluft und Klima; Innenraumluft; Wasserressourcen, Boden, Lebensmittel, ionisierende Strahlung; Lärm sowie Stoffe und Zubereitungen. Das Programm soll eine Arbeitsgrundlage für die weitere Entwicklung des Politikfeldes Umwelt und Gesundheit bilden. Die weitere Ausgestaltung um Umsetzung des Programms wird in intensivem Diskurs mit allen Beteiligten und Betroffenen erfolgen.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Forschung im Ingenieurwesen 63 (1997), S. 202-205 
    ISSN: 1434-0860
    Source: Springer Online Journal Archives 1860-2000
    Topics: Technology
    Description / Table of Contents: Abstract  A mixed-signal algorithm for low-pass filtering is proposed in this paper. This algorithm shows the same behavior for a large number of signals as the low pass. For this reason the algorithm is suitable for the low pass filtering of signals with finite energy.
    Notes: Zusammenfassung  In der vorliegenden Arbeit wird ein Mixed-Signal-Verfahren für die Tiefpaßfilterung vorgeschlagen. Dieses Verfahren besitzt für eine große Klasse von Signalen das gleiche Verhalten wie der ideale Tiefpaß. Damit eignet sich das Verfahren zur Tiefpaßfilterung von Signalen mit endlicher Energie.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 81 (1998), S. 263-270 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents In this paper the behaviour of the causal variant of the ideal low-pass is investigated. It is shown that this system is not stable with respect to the energy norm. An input signal with finite energy is given in the paper such that the output signal has an infinite energy. This result solves a problem proposed by Professor Mathis.
    Notes: Übersicht In der Arbeit wird gezeigt, daß die kausale Variante des idealen Tiefpasses ein bezüglich der energetischen Norm instabiles System ist. Es wird ein Eingangssignal mit endlicher Energie angegeben, so daß das Ausgangssignal eine unendliche Energie besitzt. Dieses Resultat löst eine Problemstellung von Professor Mathis.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 81 (1998), S. 263-270 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Description / Table of Contents: Contents In this paper the behaviour of the causal variant of the ideal low-pass is investigated. It is shown that this system is not stable with respect to the energy norm. An input signal with finite energy is given in the paper such that the output signal has an infinite energy. This result solves a problem proposed by Professor Mathis.
    Notes: Übersicht In der Arbeit wird gezeigt, daß die kausale Variante des idealen Tiefpasses ein bezüglich der energetischen Norm instabiles System ist. Es wird ein Eingangssignal mit endlicher Energie angegeben, so daß das Ausgangssignal eine unendliche Energie besitzt. Dieses Resultat löst eine Problemstellung von Professor Mathis.
    Type of Medium: Electronic Resource
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