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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 1158-1162 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The axial magnetic compression experiment of the field-reversed configuration (FRC) plasma is reported. The FRC produced in the theta-pinch system is translated into the confinement region. The separatrix length of the translated FRC is decided by the mirror distance. The compression is done in a manner as shortening the distance in time. The compression coil is installed inside the chamber to raise the strength of the confinement field at the neighborhood of the mirror. The mirror distance is compressed to be 70% of the original one. The increment of the separatrix radius is observed to be 14%. This is nearly consistent with the adiabatic calculation. The decay rate of the radius has a constant value. From the line integrated density signal measured by the interferometer, no n=2 rotational instability is observed even in the case of the compression. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 5 (1998), S. 3649-3655 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Plasma parameters, particle end loss flux, flow velocity, and pressure are measured using a radial array of magnetic probes and directional electrostatic probes, in order to investigate particle loss processes in the edge layer of a field-reversed configuration (FRC). A plasma flow toward the end region is detected outside the separatrix between the axial midplane and the end region. The exhaust flow is also found in the end region. These results imply that particles are lost radially across the separatrix and then axially to the end. Measured flow velocity in the end region agrees within an error of 20% with the fluid-theory prediction, in which isentropy and axial momentum balance along magnetic flux tubes are assumed. The existence of the sonic condition in the end region is also suggested, analogous to ordinary fluid flow in a nozzle. The magnetic flux embedded in the edge layer of the confinement region and in the end region agrees within an error of 30%. These results indicate the applicability of the magnetohydrodynamics (MHD) theory for particle end loss. The end loss time along the open field agrees with the MHD prediction within an error of 20%. The measured particle loss flux from the end region is explained by the MHD theory within an error of 20%. The plasma outside the separatrix is considered to behave as hydrodynamic flow through the magnetic loss channel, contrary to the previous work [L. C. Steinhaur, Phys. Fluids 29, 3379 (1986)]. It seems that the magnetic mirror field improves the particle confinement in the edge plasma of the FRC and thus assist the FRC confinement as previously predicted [Slough et al., Nucl. Fusion 24, 1537 (1984)]. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 6 (1999), S. 4672-4678 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A two-dimensional magnetohydrodynamic (MHD) simulation of an axial magnetic compression on a field-reversed configuration (FRC) plasma is carried out for the parameter range of a corresponding experiment conducted on the FRC Injection Experiment (FIX) [S. Okada et al., 17th IAEA Fusion Energy Conference 1998 (International Atomic Energy Agency, Vienna) (in press)]. The simulation results show that during the initial stage of the magnetic compression the front part of the FRC plasma is mainly compressed radially, and that after this stage, the compression is primarily axial. Of particular interest is expected that the closed magnetic flux surfaces of the FRC can be retained without any degradation during the magnetic compression process. Further, it is observed in the simulation that the axial magnetic compression enables a transition of the MHD equilibrium from a long and thin to a short and fat FRC. The effects of this magnetic compression on FRC plasmas are discussed. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 8 (2001), S. 3630-3634 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Adiabatic magnetic compression experiments on a field-reversed configuration (FRC) plasma are reported. The compression is performed on a long FRC held in a straight mirror field. The separatrix length of the FRC is limited by the distance between the magnetic mirrors. The mirror distance is compressed in time to 35% of the original one by the compression coil installed inside the chamber, and the separatrix length is shortened to 38%. The separatrix radius of the compressed FRC increases by 56% and the aspect ratio (separatrix length/separatrix diameter) changes from 12.6 to 4.1. Magnetic probes with the compensation circuit are utilized to investigate the dynamic transition phase during the compression. The transition process is found from these measurements to be divided into three stages, where a new equilibrium state is achieved in the final stage. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 2294-2297 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The first experimental result of high power (14 kV, 23 A) neutral beam (NB) injection into a high-beta field-reversed configuration (FRC) is demonstrated. The result makes it clear that the NB injection improves the plasma performance, increasing the configuration lifetime more than 200% in comparison with the ordinary FRC under similar conditions. A novel NB injection system is presented for application to FRC plasmas. A set of three concave electrodes for beam extraction is used to focus the beam enabling to pass through a narrow port. The target of beam injection is a large bore FRC plasma contained in a mirror field with a mirror ratio of 2–9. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 7 (2000), S. 4062-4069 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Two-dimensional numerical equilibria of field-reversed configuration (FRC) plasmas in the strong mirror field applied externally are studied by means of the Grad–Shafranov equation. Appropriate choice of the pressure function is necessary to obtain a thin and elongated equilibrium, as observed in the FRC Injection Experiment (FIX) [H. Himura et al., Phys. Plasmas 2, 191 (1995)]. To solve the Grad–Shafranov equation, the finite difference method is used, applying the boundary-fitted curvilinear coordinates and the attracted grids near the separatrix. The outstanding feature of the equilibria is the presence of a narrow and sharp spike in the toroidal current profile near the separatrix. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: The new ion energy analyzer is developed to measure the energy distribution function f(E(parallel),E⊥) of ions lost along the confinement magnetic field [M. Okubo et al., J. Plasma Fusion Res. 70, 1102 (1994)]. The end-loss ions have larger E⊥ components compared with their E(parallel) components in the magnetic mirror throat. In this case, the ion energy distribution function is distorted because of the incident angle dependency of the retarding grid transmission. We try to compensate a measured energy distribution function by calculated grid transmission functions. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 66 (1995), S. 1602-1604 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Pulse operation of electron cyclotron resonance plasma was performed for the fabrication of diamond films by chemical vapor deposition. With square wave amplitude modulation of microwaves at 500 Hz in frequency, the growth rate became twice as large as one of continuous operation with the same microwave power. Time resolved measurement of the optical emission from the pulse modulated plasma was also carried out. © 1995 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The hypertrophy/hyperplasia of airway smooth muscle (ASM) cells is one of the characteristic features of bronchial asthma. This structural change leads to the thickening of airway walls resulting in the amplification of airway narrowing. However, the pathogenesis of this structural change has not yet been determined. Eosinophils, which play a pathogenic role in asthma, have been demonstrated to have proliferative effects on fibroblasts and vascular smooth muscle cells.Objective We attempted to investigate the potential of eosinophils to induce the proliferation of ASM cells.Methods We examined the effect of lysates of eosinophils purified from peripheral blood of healthy donors on cultured human ASM cell proliferation.Results Eosinophil lysates significantly induced ASM cell proliferation in time- and dose-dependent manners, reaching a maximum on day 6 at 50% of eosinophil lysates (6.0 ± 0.7 × 104[mean ± SD] /well, n = 5 vs. 4.5 ± 1.1 × 104/well, n = 5; P 〈 0.05). This proliferative activity was heat-sensitive and recovered in the soluble fraction of the eosinophil lysates. Furthermore, the molecular weight of the mitogenic activity in the soluble fraction was identified as lower than 10 kDa. The inhibitory activity to ASM cell proliferation was also found in the insoluble fraction of the lysates.Conclusion These results indicate that circulating eosinophils store mitogenic activity for ASM cells, suggesting that eosinophils might contribute to the development of the hyperplasia of ASM cells in asthmatics through the release of the stored mitogenic activity upon stimulation at the site of inflammation.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Airway remodelling in asthma such as subepithelial fibrosis is thought to be the repair process that follows the continuing injury as of chronic airway inflammation. However, how acute allergic inflammation causes tissue injury in the epithelial basement membrane in asthmatic airways remains unclear. Matrix metalloproteinases (MMPs) capable of degrading almost all of the extracellular matrix components have been demonstrated to be involved in cell migration through the basement membrane in vivo and in vitro.Objective We investigated the alterations of matrix construction and the role of MMPs in matrix degradation in the subepithelium during acute allergic airway inflammation.Methods Airway inflammation, the ultrastructure of the subepithelium and injury of types III and IV collagen in tracheal tissues from ovalbumin (OVA)-sensitized mice after OVA inhalation with or without the administration of tissue inhibitor of metalloproteinase-2 (TIMP-2) and dexamethasone were evaluated by cell counting in bronchoalveolar lavage (BAL) fluids, electron microscopy and immunohistochemistry, respectively.Results The disruption of the lamina densa and matrix construction and the decrease of the immunoreactivity for type IV collagen in subepithelium were observed in association with the accumulation of inflammatory cells in airways 3 days after OVA inhalation. This disorganization of the matrix components in the subepithelium, as well the cellular accumulation, was abolished by the administration of TIMP-2 and dexamethasone. The immunoreactivity for type IV collagen in the subepithelium in OVA-inhaled mice returned to the level of that in saline-inhaled mice 10 days after inhalation in association with a decrease of the cell numbers in the BAL fluid. The immunoreactivity for type III collagen was changed neither 3 nor 10 days after OVA inhalation.Conclusion These results suggest that epithelial basement membrane gets injured by, at least in part, MMPs as a consequence of cell transmigration through the membrane during acute allergic airway inflammation.
    Type of Medium: Electronic Resource
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