Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Characterization of AlxGa1−xAs/GaAs heterojunction bipolar transistor structures using cross-sectional scanning force microscopy (2000)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 1937-1942 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have characterized base-layer width and dopant distributions on cleaved cross-sections of AlxGa1−xAs/GaAs heterojunction bipolar transistor (HBT) structures using a variation of electrostatic force microscopy. The contrast observed is sensitive to the local dopant concentration through variations in the depletion layer depth extending into the sample surface, and enables delineation of individual device regions within the epitaxial layer structure with nanoscale spatial resolution. In two epitaxially grown HBT structures, one with 50 nm base width and the other with 120 nm base width, we are able to delineate clearly the emitter, base, collector, and subcollector regions, and to distinguish regions within the collector differing in dopant concentration by a factor of two. We have also distinguished clearly between the base widths in these samples and have precisely measured the difference to be 63±3 nm, in excellent agreement with the nominal difference of 70±7 nm. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.372116
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    The Use of an Oral Fluid Immunoglobulin G ELISA for the Detection of Helicobacter pylori Infection in Children (2002)
    Oxford, UK : Blackwell Science Ltd
    Helicobacter 7 (2002), S. 0 
    Details
    ISSN: 1523-5378
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background. Enzyme linked immunosorbent assay (ELISA) evaluation of oral fluid immunoglobulin G (IgG) antibodies to Helicobacter pylori is a unique approach for both epidemiological studies and the diagnosis of infection, especially in children. The use of oral fluid sampling to evaluate specific H. pylori IgG antibodies has advantages over serum, including reduced biohazard risk and noninvasive collection. Oral fluid sampling is fast and involves minimal patient discomfort. Since children facilitate transmission of H. pylori infection, a simple, accurate, noninvasive diagnostic test is necessary for large epidemiologic studies. The aim of our study was to evaluate a new oral fluid ELISA for detection of IgG antibodies to H. pylori in children.Materials and methods. We compared this new oral fluid ELISA with the HM-CAPTM serum ELISA and gastric biopsy histology using 779 oral fluid samples from children collected at 11 clinical sites across the United States. This cohort included 315 children symptomatic for abdominal pain and 464 asymptomatic. All samples were evaluated in a double blind manner. The oral fluid ELISA demonstrated a sensitivity of 76.2% and a specificity of 94.0% in children 2 months old to 201/2 years, as compared with the HM-CAPTM serologic assay. The assay’s sensitivity improved to 81.3% in children aged 5 or greater and the specificity remained at 94.0%. When compared with gastric biopsy histology in the same age group, the oral fluid ELISA demonstrated a sensitivity of 71.7% and a specificity of 90.4%.Results. This new oral fluid ELISA is moderately sensitive and offers a very specific method for detecting H. pylori infection in older children, but it is of little value in children under the age of 5 years.Conclusions. Overall, we conclude that this oral fluid ELISA does not appear to be a helpful clinical tool for the diagnosis of H. pylori infection in children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1083-4389.2002.00062.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Crystallization and preliminary X-ray diffraction studies of the influenza C virus glycoprotein (1996)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 52 (1996), S. 1041-1045 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Influenza C virus contains a single surface glycoprotein in its lipid envelope which is the hemagglutinin-esterase-fusion glycoprotein (HEF). HEF binds cell-surface receptors, is a receptor-destroying enzyme (a 9-O-acetylesterase), and mediates the fusion of virus and host cell membranes. A bromelain-released soluble form of HEF has been crystallized. Two different tetragonal forms have been identified from crystals with the same morphology [P1(3)22, a = b = 154.5, c = 414.4 Å, and P41(3)212, a = b = 217.4, c = 421.4 Å]. Both crystal forms share a common packing scheme. Synchrotron data collection and flash cooling of crystals have been used for high-resolution data collection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444996005021
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Kutane Reaktionen bei Morbus Crohn Vaskulitiden verschiedener Etagen des Hautorgans (1997)
    Springer
    Der Hautarzt 48 (1997), S. 328-331 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Morbus Crohn ; Ileitis terminalis ; Kutane Vaskulitis ; Purpura Schönlein-Henoch ; Erythema nodosum ; Key words Crohn disease ; Ileitis terminalis ; Cutaneous vasculitis ; Schönlein-Henoch purpura ; Erythema nodosum
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Two young female patients presented with recurrent erythema and Henoch-Schönlein purpura respectively. In both cases clinical, histological and radiological showed relatively mild, but previously undiagnosed Crohn’s disease as a trigger. We describe the treatment of the underlying disease and the symptomatic treatment of skin lesions. Categories of specific and unspecific skin lesions associated with Crohn’s disease, as described in the literature, are presented. Vasculitic changes of the deep versus the superficial dermal plexus are discussed.
    Notes: Zusammenfassung Wir berichten über 2 junge Patientinnen mit rezidivierendem Erythema nodosum, bzw. Purpura-Schönlein-Henoch unklarer Genese. Bei der klinischen, histologischen und radiologischen Diagnostik zeigte sich in beiden Fällen als Trigger ein relativ mild verlaufender, bisher nicht erkannter Morbus Crohn. Die spezifische Therapie der Grunderkrankung bzw. symptomatische Behandlung der Hauterscheinungen wird beschrieben. Die Einteilung der spezifischen und unspezifischen Crohn-assoziierten Hautsymptome in der Literatur wird dargestellt, und die vaskulitischen Veränderungen des tiefen versus des oberflächlichen dermalen Gefäßplexus werden diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050591
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Liver transplantation for the treatment of urea cycle disorders (1998)
    Springer
    Journal of inherited metabolic disease 21 (1998), S. 112-118 
    Details
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The principal goal of therapy when liver transplantation is used for the treatment of metabolic disease is to correct the metabolic error. By doing so, liver transplantation eliminates the hepatic and peripheral consequences of the error. Inborn errors involving the urea cycle appear on theoretical grounds to be amenable to treatment using liver transplantation and, indeed, published data demonstrate that this approach to therapy can be successful. The purpose of this study is to examine the outcome of liver transplantation done for the indication of urea cycle defects in a large group of patients. The first goal of the study is to determine with certainty that liver transplantation corrects hyperammonaemia and halts the progress of disease. A second goal is to determine the extent of neurological recovery in children previously injured by hyperammonaemia. The final goal is to understand whether the quality of life is improved and medical expense is reduced by transplantation. The study involved a survey of major transplantation centres. Four centres provided data about 16 patients, 14 of whom were alive 11 months to 6 years after transplantation. The results demonstrate that liver transplantation resulted in correction of hyperammonaemia in all patients. The neurological outcome after transplantation correlated closely with the condition prior to transplantation. This population of patients has had relatively few problems in the long term related to the liver transplant itself. The quality of life seems to be much improved, but further study will be needed to confirm this. Limited data involving two patients show a reduction in the cost of care. We conclude from our experience that liver transplantation can be an effective treatment for children with urea cycle defects.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1005317909946
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...