Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 2000-2004
  • 1990-1994  (3)
  • Polymer and Materials Science  (2)
  • (Dichloromethylene)bisphosphonate  (1)
  • Brillouin spectroscopy of ultraoriented poly(ε-caprolactone) films  (1)
Material
Years
  • 2000-2004
  • 1990-1994  (3)
Year
Keywords
  • 1
    ISSN: 1432-0851
    Keywords: Liposomes ; (Dichloromethylene)bisphosphonate ; Kupffer cells ; Metastatic growth ; Liver
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The evidence that Kupffer cells are capable of controlling metastatic growth in the liver in vivo is largely circumstantial. The best approach when studying natural cytotoxicity activities of Kupffer cells is to investigate the effect of Kupffer cell elimination on tumour growth. Until now it has not been possible to eliminate Kupffer cells without affecting other cell populations. We have recently developed a new method to eliminate Kupffer cells selectively: intravenous injection of liposome-encapsulated (dichloromethylene)bisphosphonate (Cl2MDP-liposomes) leads to effective elimination of all Kypffer cells, without affecting non-phagocytic cells. Wag/Rij rats were injected with Cl2MDP-liposomes. After 48 h, rats were inoculated with syngeneic CC531 colon carcinoma cells by injection in the portal system. The results show a strongly enhanced tumour growth in the liver of the Cl2MDP-liposometreated rats. In these animals, livers were almost completely replaced by tumour and had increased in weight, whereas in the control groups only a few (four to eight) small (1-mm) tumour nodules were found. These data show that selective elimination of Kupffer cells results in enhanced tumour growth in the liver, implying that Kupffer cells play a crucial role in controlling tumour growth in the liver.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 30 (1992), S. 1173-1176 
    ISSN: 0887-6266
    Keywords: poly(ε-caprolactone) films on highly oriented PTFE substrate ; Brillouin spectroscopy of ultraoriented poly(ε-caprolactone) films ; crystallization of ultra-oriented poly(ε-caprolactone) on PTFE sustrate ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    Electronic Resource
    Electronic Resource
    Bognor Regis [u.a.] : Wiley-Blackwell
    Journal of Polymer Science Part B: Polymer Physics 31 (1993), S. 505-512 
    ISSN: 0887-6266
    Keywords: ferroelectric copolymers ; Brillouinspectroscopy ; irradiation ; acoustic properties ; molecular orientation ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Acoustic, opto-acoustic, and x-ray investigations have been performed in order to study the influence of irradiation, electrical poling, and mechanical orientation on the morphology of ferroelectric random copolymers of vinylidene fluoride and trifluorethylene {P[VDF/TrFE] (70/30)}. The influences of these different treatments on the molecular orientation distribution of the amorphous and crystalline phases are discussed, as well as their influences on the crystallinity of the material. The elastic stiffness and the related viscosity tensors of P[VDF/TrFE] (70/30), the elastic stiffness modulus of the amorphous matrix, and the hierarchy of stiffness constants of the crystalline state have been determined. © 1993 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...