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Identification of novel polymorphisms in the AXIN1 and CDX-2 genes (2000)

Lin, Y.-M. ; Kato, T. ; Satoh, S. ; [et al.]

Springer

Journal of human genetics 45 (2000), S. 254-256

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ISSN: 1435-232X

Keywords: Key words Single nucleotide polymorphism ; Colorectal cancer ; Hepatocellular carcinoma ; Axin ; Cdx-2

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Abstract Axin and Cdx-2 play important roles in the tumorigenesis of human liver and colon. We have identified seven novel single-nucleotide polymorphisms (SNPs) in the AXIN1 gene and three in the CDX-2 gene. The identification of SNPs in these cancer-associated genes establishes a basis for future investigations to detect losses of heterozygosity in tumors; these SNPs may also provide genetic background information associated with cancer risk.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/s100380070036

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