ZIB

Treffer pro Seite

Treffer 1 - 3 | 3 Treffer

Sortierung

Digitale Medien

Acetylcholine-sensitivity and local regenerative activity in denervated frog slow muscle fibres (1984)

Lehouelleur, J. ; Noireaud, J. ; Schmidt, H.

Springer

Pflügers Archiv 402 (1984), S. 88-93

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1432-2013

Schlagwort(e): Slow muscle fibres ; Denervation ; ACh-sensitivity ; Local electrical activity

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract 1. The distribution of acetylcholine (ACh)-sensitive membrane areas was determined in 11–75 days denervated slow muscle fibres ofRana temporaria by iontophoretic application of acetylcholine. The fibres were also stimulated directly, and their electrical activity was recorded with an intra- and an extracellular electrode. 2. During the first two weeks following denervation the size of the ACh-sensitive fibre surface was similar to that of normal slow fibres, but a spreading out of ACh-sensitivity occurred between the 13th and 20th day. 3. The slow fibre membrane did not become homogeneously ACh-sensitive; even after long periods of denervation large local sensitivity gradients could be observed. Throughout the denervation period maximum values of ACh-sensitivity were in the same range as in normal slow fibres. 4. Action potentials were fully developed when ACh-sensitivity started to spread out. Extracellularly recorded inward currents varied in amplitude along the fibre surface, and either one or two peaks were observed in individual fibres. 5. The spatial relationship between inward current peaks and peaks of ACh-sensitivity was investigated in 12 fibres. Fifteen inward current peaks were located at distances of 30–640 μm from points of maximum ACh-sensitivity; only once did the centers of ACh-sensitivity and excitability coincide. 6. It is concluded that Na channels are incorporated into nonjunctional membrane areas of denervated slow fibres; this process preceds the incorporation of ACh-receptors by approximately one week.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00584836

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Digitale Medien

Oxidation of Alcohols with Benzyl(triethyl)ammonium Permanganate (1981)

Schmidt, H.-Jürgen ; Schäfer, Hans J.

Weinheim : Wiley-Blackwell

Angewandte Chemie International Edition in English 20 (1981), S. 104-104

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 0570-0833

Schlagwort(e): Chemistry ; General Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Zusätzliches Material: 1 Tab.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/anie.198101041

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Digitale Medien

Oxidation of Amines with Benzyl(triethyl)ammonium PermanganateDedicated to Professor Wilhelm Klemm on the occasion of his 85th birthday (1981)

Schmidt, H.-Jürgen ; Schäfer, Hans J.

Weinheim : Wiley-Blackwell

Angewandte Chemie International Edition in English 20 (1981), S. 109-109

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 0570-0833

Schlagwort(e): Chemistry ; General Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Zusätzliches Material: 1 Tab.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/anie.198101091

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 3 | 3 Treffer