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  • 2000-2004
  • 1980-1984  (3)
  • Affective disturbances/etiology  (1)
  • Chronotherapy  (1)
  • Ehrlich ascites-tumor  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Annals of hematology 43 (1981), S. 85-88 
    ISSN: 1432-0584
    Keywords: Lewis lung carcinoma ; Circadian growth rhythm ; Cyclophosphamide ; Chronotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Lewis lung carcinoma cells show marked diurnal growth variations with a peak of DNA synthetizing activity between 8.00 and 12.00 p.m. Therapy with cyclophosphamide is most effective at 8.00 a.m. and 8.00 p.m. Preliminary results show that this diurnal rhythm cannot be altered by abolition of the light and dark periods.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Ehrlich ascites-tumor ; Hypercaloric feeding ; Proliferation kinetics of tumor cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Oral feeding of mice with hypercaloric diets inhibited growth of a hyperdiploid Ehrlich ascites tumor significantly and modified proliferation kinetics of tumor cells if feeding started 7 days before tumor transplantation. Furthermore, the tumor take rate was significantly reduced. The 4 hypercaloric diets contained as main energy sources carbohydrates, or unsaturated fatty acids, or saturated fatty acids, or a mixture of these substrates. Inhibition of tumor growth was not observed if hypercaloric feeding started on the same day the tumor transplantation occurred. Tumor bearing animals lived significantly longer compared to controls if they are on a hypercaloric diet with unsaturated fatty acids as main energy source. Survival was not influenced by the time feeding started. That means that partial prevention of cachexia was the main reason for longer survival. Feeding with a diet poor in proteins led in both experimental sets to a statistically not significant shortening of the median survival time compared to controls.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European archives of psychiatry and clinical neuroscience 230 (1981), S. 339-349 
    ISSN: 1433-8491
    Keywords: Haemodialysis ; Depression/etiology ; Affective disturbances/etiology ; MMPI/comparative study ; Human ; Hämodialyse ; Depression/Ätiologie ; Stimmungsschwan ; kungen/Ätiologie ; MMPI/vergleichende Studie ; Mensch
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 32 ambulante Hämodialyse-Patienten wurden über einen Zeitraum von 8 Tagen mehrfach täglich durch psychometrische Fremd- und Selbstbeurteilungsskalen in ihrer Befindlichkeit eingeschätzt. Ziel der Untersuchung war es, depressive Verstimmungen in ihrer Häufigkeit und Ausprägung bei Hämodialyse-Patienten zu erfassen. Es sollte zudem geprüft werden, inwieweit derartige depressive Verstimmungen zur Frage der biochemischen Determiniertheit von depressiven Syndromen beitragen können. Es fanden sich subjektiv erlebte kurzfristige depressive Stimmungsschwankungen in etwa 15% der Fälle, die in den psychometrischen Fremdbeurteilungen jedoch nicht zu objektivieren waren. Derartige depressive Verstimmungen sind somit als „Modelldepression“ für die biologische Depressions-Forschung nicht geeignet. Geringe Häufigkeit und Schwere der depressiven Verstimmungen, sowie psychopathologischer Längs- und Querschnitts-befund lassen die Hämofiltration als wesentlichen Depressionsfaktor im Sinne der Katecholamin-/Indolamin-Mangel-Hypothese unwahrscheinlich erscheinen.
    Notes: Summary Over a period of 8 days, 32 haemodialysis out-patients were studied. Psychometric alien- and self-rating questionnaires were completed twice a day. The aim of the study was to produce a survey of the frequency and severity of depression in haemodialysis patients. It was speculated that the potency of haemodialysis in producing depression might be a helpful model in searching for biochemical factors in this disorder. Self-ratings showed short-term depressive changes in mood in about 15% of cases, which were not confirmed by alien-rating scales. It is concluded that neither incidence and severity nor longitudinal and cross-sectional profiles support a biochemical determination of depression in haemodialysis patients.
    Type of Medium: Electronic Resource
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