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  • 1975-1979  (4)
  • 1960-1964  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 35 (1979), S. 685-686 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The inhibitory effect of various purine derivatives on PHA-induced human lymphocyte blast formation was studied. Two nucleoside cytokinins, N6-benzyladenosine and N6-isopentenyladenosine, inhibited blast formation at concentrations as low as 10−6 M. However, the other cytokinins, which lacked the ribosyl residue at N9 position, had to be at the higher molar concentration of 10−4 before they could induce the same inhibitory effect.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 35 (1979), S. 696-699 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Trans-4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) antagonized the effect of exogenous androgens on the ventral prostate (VP) in castrated rats as well as the effect of endogenous androgens in intact rats. FA, however, had no effect on the seminal vesicles (SV) and levator ani muscle (LAM), nor oestrogenic effect in female rats and mice. FA did not antagonize the receptor binding of testosterone nor inhibit the conversion of testosterone into 5α-dihydrotestosterone (DHT).
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-0428
    Keywords: Synthetic human connecting peptide ; C-peptide immunoreactivity (CPR) ; urine CPR ; blood CPR ; radioimmunoassay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A double-antibody radioimmunoassay method, using synthetic human connecting peptide as an immunizing antigen and standard, was evaluated for clinical assay of blood and urine samples. Normal fasting blood connecting peptide immunoreacivity (CPR) was 2.45±0.96 ng/ml, increasing promptly after a 50 g oral glucose load, but somewhat slower than insulin. Molar concentration of CPR exceeded that of insulin. CPR responses to glucose were subnormal in diabetics, very low in juvenile-type cases, and often poor in patients on insulin treatment. Fasting CPR levels were elevated in patients on corticosteroid treatment and with uraemia. A patient with insulin “auto-antibod” had high serum CPR. A considerable amount of CPR appeared in urine. Normal daily excretion of CPR was 1.52±0.55 μg/kg or 55.1±18.2 ng/mg creatinine. Urine CPR was very low in juvenile-type diabetics, and elevated in patients on corticosteroid treatment. The results confirm that blood and urine CPR are useful measures of the endocrine pancreatic function.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 21 (1960), S. 300-313 
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Klinische Beobachtungen an Patienten, die der präsacralen Neurektomie unterzogen wurden, um sie von der Cystalgie zu befreien, zeigten bemerkenswerte Erfolge und nur geringe Komplikationen dieses Eingriffs. Die Resultate sprechen für eine derartige Operation nach sorgfältiger Indikationsstellung. Darüber hinaus wurden die Mechanismen durch Experimente an Hunden untersucht.
    Abstract: Résumé L'observation clinique de malades qui ont été soumis à la neurectomie présacrale pour les soulager des douleurs de la vessie, a démontré l'efficacité et la rarité des complications chirurgicales. Le résultat indique que l'opération doit être faite après un triage sévère des indications. Les mécanismes d'action ont été, en outre, étudiés au moyen d'expériences sur des chiens.
    Notes: Summary A clinical observation on patients subjected to presacral neurectomy to relieve them from cystalgia showed remarkable effectiveness and slight complications. The result indicates that the operation should be performed, strictly choosing the indications. Moreover, its mechanisms were investigated by the experiment employing dogs.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1572-8838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wurden bei 187 Hunden Durchtrennungen bestimmter Anteile der Blaseninnervation vorgenommen und jeweils die hierdurch bedingten Veränderungen der Blase cystometrisch und gleichzeitig biochemisch ausgewertet. Dabei fiel auf, daß nach Durchtrennung der vorderen und hinteren Wurzeln der entsprechenden Sacralnerven mit gleichzeitiger Entfernung der Sacralganglien Blasenvolumen und Blaseninnendruck sich gleich verhielten wie nach Durchtrennung der Nn. pelvici; d. h. das Blasenvolumen sank und der Innendruck stieg an. Wurden bei Durchtrennung der hinteren und vorderen Wurzeln der Sacralnerven die Sacralganglien jedoch belassen, so stieg das Blasenvolumen an und der Innendruck fiel ab. Biochemisch wurde festgestellt, daß nach Durchtrennung der jeweiligen Blaseninnervation regelmäßig jeweils der O2-Verbrauch die CO2-Abgabe, die Bernsteinsäuredehydrogenase und die Cholinesterase in der Blase sich verminderten, während die Milchsäuredehydrogenase und die P32-Aufnahme in die energiereichen Phosphatverbindungen anstiegen. Diese Relation war nach Entfernung der Sacralganglien nicht mehr nachweisbar.
    Abstract: Résumé Chez 187 chiens nous avons sectionné des rameaux définis des nerfs innervants la vessie et déterminé les modifications consécutives sur la vessie autant au point de vue cystométrique que biochimique. Nous avons observé ainsi que la section des racines antérieures et postérieures des nerfs sacrés correspondants et l'enlèvement concomitant des ganglions sacraux amènent les mêmes modifications que celles que l'on observe après section des nerfs pelviens, à savoir une diminution du volume de la vessie et une augmentation de la pression intravésicale. En respectant les ganglions sacraux et en limitant à sectionner les sources antérieures et postérieure il y a au contraire augmentation du volume vésical et chute de la pression intravésicale. La section des nerfs innervant la vessie amène une chute de la consommation d'oxygène et de la production d'acide carbonique de la paroi vésicale ainsi qu'une diminution de l'activité de la succino-déhydrogénase et de la cholinestérase, alors que l'activité de la lacto-déhydrogènase et la vitesse d'incorporation du P32 dans les composés phosphoriques riches en énergie augmentent. Ces faits ne s'observent plus après suppression concomitante des ganglions sacraux.
    Notes: Summary In 187 dogs we cut through certain branches of the nerves innervating the urinary bladder and we determined the changes caused thereby from a cytometrical and a biochemical point of view. We thus observed that the section of the corresponding ventral and dorsal sacral nerves accompanied by the removal of the sacral ganglions brought about the same changes as those observed after section of the pelvic nerves, i. e., a diminution of the volume of the urinary bladder and an augmentation of the intravesical pressure. Leaving the sacral ganglions and restricting ourselves to the section of the ventral and dorsal roots, we ascertained, however, an augmentation of the vesical volume a diminution of the intravesical pressure. The section of the nerves innervating the urinary bladder brought about a diminution of the consumption of oxygen and of the production of carbonic acid of the vesical wall as well as a diminution of the activity of the succinodehydrase and of the cholinesterase while the activity of the lacto-dehydrase and the speed of incorporation of the P32 into the phosphoric compounds rich in energy augmented. These facts were no more observed after the simultaneous suppression of the sacral ganglions.
    Type of Medium: Electronic Resource
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