ISSN:
1435-232X
Keywords:
Key words Single nucleotide polymorphism
;
Colorectal cancer
;
Hepatocellular carcinoma
;
Axin
;
Cdx-2
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Axin and Cdx-2 play important roles in the tumorigenesis of human liver and colon. We have identified seven novel single-nucleotide polymorphisms (SNPs) in the AXIN1 gene and three in the CDX-2 gene. The identification of SNPs in these cancer-associated genes establishes a basis for future investigations to detect losses of heterozygosity in tumors; these SNPs may also provide genetic background information associated with cancer risk.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s100380070036
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