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  • 2000-2004  (2)
  • 1960-1964
  • 1925-1929
  • Key words Holoprosencephaly  (1)
  • Vaccination programs  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Der Gynäkologe 33 (2000), S. 560-564 
    ISSN: 1433-0393
    Keywords: Schlüsselwörter Impfziele ; Impfplan ; Impferfolg ; Unerwünschte Nebenwirkungen des Impfens ; Keywords Vaccination aims ; Vaccination programs ; Vaccination success ; Undesirable side effects of vaccination
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Vaccination is one of the most powerful strategies in medical prevention. Although wide-scale vaccination programs have failed in the German population, real opponents to vaccination in our country are in the minority. An adequate vaccination protocol is important not only medically, but also cost-effective from a public health perspective. The lack of a vaccination programs as in other European countries represents a major, critical deficiency which should be rectified in Germany.
    Notes: Zusammenfassung Kaum eine andere Maßnahme wie die Impfung hat größeren präventiven medizinischen Charakter. Während eine Durchimpfung der Bevölkerung in Deutschland in vielen Bereichen nicht gelungen ist, sind tatsächliche Impfgegner in unserem Lande nur in einer Minderheit vorhanden. Gute Impfkonzepte sind nicht nur aus medizinischer Sicht richtig, sondern in der gesellschaftlichen Betrachtung auch kosteneffizient. Der Mangel in unserem Land ist, dass ein Impfprogramm fehlt, wie es in anderen Ländern, auch in Europa, bereits vorliegt. Aus diesem Grunde muss ein Impfkonzept in Deutschland durchgesetzt werden.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Key words Holoprosencephaly ; Aprosencephaly ; Pseudo-aprosencephaly ; Teratology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two cases out of a sample of 41 fetuses and infants with prosencephalic malformation, observed at the Institute of Pathology and Department of Neuropathology of the University of Heidelberg, are described here in detail. These cases presented grossly with microcephaly and missing forebrain, appearing to be cases of aprosencephaly. However, in one of these cases glio-mesenchymal membranes with an ependymal outline, consistent with the microscopic appearance of the dorsal sac membrane in holoprosencephaly and obviously representing remnants of a collapsed primitive prosencephalic vesicle, could be demonstrated. In the other case only hindbrain structures, with the exception of the cerebellum, were present without any demonstrable remnants of a prosencephalon. We propose that the microscopic specification of a primitive prosencephalic vesicle in the first case and similar cases does not justify the diagnosis of atelencephaly/aprosencephaly because the prosencephalon was not really missing (pseudo-aprosencephaly). The prosencephalic anlage had been formed but remained vesicular without further differentiation of a holospheric brain mantle as in common holoprosencephaly (‘vesicular forebrain’). We believe that pseudo-aprosencephaly represents the most primitive form of holoprosencephaly, in which the forebrain remains as a complete sac, linking classical holoprosencephaly with ‘true’ aprosencephaly, i.e., defective prosencephalic anlage due to developmental arrest. The ‘vesicular forebrain’ allows one to extend the classification of Probst by an additional category which might be termed complete sac category, intercalated between the dorsal sac category and ‘true’ atelencephaly/aprosencephaly.
    Type of Medium: Electronic Resource
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