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  • 2000-2004  (4)
  • elasmobranch  (2)
  • Microarray Gene expression Structural analysis Geometry  (1)
  • aspartic acid  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Functional & integrative genomics 1 (2000), S. 174-185 
    ISSN: 1438-7948
    Keywords: Microarray Gene expression Structural analysis Geometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract. A microarray experiment gives a snapshot of the state of an organism in terms of the relative abundances of its mRNA transcripts, locating the organism at a point in a high dimensional state space where each axis represents the relative expression level of a single gene. Multiple experiments generate a cloud of points in this gene expression space. We present a geometric approach to analyzing the covariational properties of such a cloud and use a dataset from Saccharomyces cerevisiae as an illustration. In particular, we use singular value decomposition to identify significant linear sub-structures in the data and analyze the contributions of both individual genes and functional classes of genes to these major directions of variation. Analyzing the publicly available yeast expression data, we show that under all experimental conditions the variation in expression is limited to a small number of linear dimensions. Projections of individual gene axes onto the significant dimensions can order the contribution of individual genes to variation in expression within an experiment. We show that no particular groups of genes characterize particular experimental conditions. Instead, the particular structure of the coordinated expression of the entire genome characterizes a particular experiment.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Topics in catalysis 13 (2000), S. 175-177 
    ISSN: 1572-9028
    Keywords: diketopiperazines ; hydrogenation ; amino acid ; aspartic acid ; chiral auxiliary
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The dehydrodiketopiperazines 6 undergo face selective hydrogenation with a 5% palladium on carbon catalyst to give the diketopiperazines 7 in high yield with excellent diastereoisomeric ratios (〉97%).
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-5133
    Keywords: movement behavior ; tracking ; elasmobranch ; ultrasonic telemetry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We used ultrasonic telemetry to determine the movement directions and movement rates of leopard sharks, Triakis semifasciata, in Tomales Bay, California. To analyze tide and time of day effects, we surgically implanted transmitters in the peritoneal cavities of one male and five female leopard sharks, which we located during summer for three to five sampling sessions lasting 12 to 24 h each. All leopard sharks showed strong movement direction patterns with tide. During incoming tides, sharks moved significantly (p〈0.0001) towards the inner bay, apparently to exploit the extensive inner bay muddy littoral zones' food resources. On outgoing tides, sharks showed significant (p〈0.0001) movements towards the outer bay. During high tide, there was no discernible pattern to their movements (p=0.092). Shark movement rates were significantly (p〈0.0001) greater during dark periods (mean±SE: 10.5±1.0 m min−1), compared with fully lighted ones (6.7±0.5 m min−1). Movement rates of longer sharks tended to be greater than those of shorter ones (range means±SE: 5.8±0.6 m min−1 for the 91 cm shark, to 12.8±1.6 m min−1 for the 119 cm shark), but the leopard sharks' overall mean movement rate (8.1±0.5 m min−1) was slower than other (more pelagic) sharks.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-5133
    Keywords: elasmobranch ; movement behavior ; Myliobatidae ; tracking ; ultrasonic telemetry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract We used ultrasonic telemetry to examine movement patterns of 11 bat rays, Myliobatis californica, in Tomales Bay, California. Tomales Bay is long (20 km) and narrow (1.4 km), and is hydrographically separated into outer and inner bay regions. The outer bay (the outermost 8 km) is characterized by oceanic conditions while the shallow inner bay (the innermost 12 km) features wide seasonal temperature shifts. Five rays were tracked monthly from October 1990 to November 1991 and six rays (four of which carried temperature-sensing transmitters) were tracked daily from 30 June to 16 July 1992. Mean bat ray movement rate was 8.84 m min−1 (range 4.49 to 13.40 m min−1) and was not significantly affected by size (p=0.592), tidal stage (p=0.610), or time of day (p=0.327). Movement direction was unrelated to tidal stage (p=0.472) but showed a highly significant diel pattern (p〈0.001). From 2:50–14:50 h, rays moved toward the warmer and shallower inner bay, while from 14:50–2:50 h they moved toward the cooler and deeper outer bay. These telemetry data, along with known bat ray foraging patterns and respiratory temperature-sensitivity, argue for behavioral thermoregulation as the primary influence on this movement pattern.
    Type of Medium: Electronic Resource
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