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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 236 (1998), S. 513-521 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract · Background: Central serous chorioretinopathy is characterized on indocyanine green angiography by areas of transient choroidal hyperfluorescence. These findings are thought to be the consequence of altered permeability of the choroidal vessels. · Methods: The indocyanine green angiograms of 41 patients between 40 and 60 years of age, with central serous chorioretinopathy and of 120 patients above 64 years of age with occult choroidal neovascularization due to age-related macular degeneration were reviewed for the presence of transient indocyanine green leakage. Twelve eyes of 9 patients above 64 years of age with (1) fluorescein leakage of undetermined source corresponding with well-delineated zone(s) of retinal pigmentary changes and (2) transient indocyanine green hyperfluorescence are reported in detail. · Results: Transient indocyanine green hyperfluorescence was seen in all eyes with central serous chorioretinopathy, either typical or chronic, and was seldom seen in occult choroidal neovascularization due to age-related macular degeneration. In the series of chronic serous chorioretinopathy in patients above 64 years of age, four classic choroidal neovascular membranes were found in 12 eyes. Most patients presented multizonal transient choroidal hyperfluorescence in both eyes on indocyanine green angiography. · Conclusion: Transient choroidal hyperfluorescence is suggestive for chronic central serous chorioretinopathy in older patients presenting retinal pigmentary disease with fluorescein leakage of undetermined source. Chronic central serous chorioretinopathy is not uncommonly associated with classic choroidal neovascularization in the elderly.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Graefe's archive for clinical and experimental ophthalmology 236 (1998), S. 346-353 
    ISSN: 1435-702X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  · Background: The main cause of vision loss in patients with angioid streaks is choroidal neovascularization and subsequent macular degeneration. Indocyanine green angiography allows visualization of the choroidal circulation and may be superior to fluorescein angiography in the evaluation of patients with angioid streaks. · Methods: The ophthalmoscopic, fluorescein and indocyanine green angiographic characteristics of angioid streaks were studied in 34 patients with such streaks. Nineteen patients had pseudoxanthoma elasticum and 15 patients had isolated angioid streaks. The fluorescence characteristics of the ’peau d’orange’ and of choroidal neovascularization, when present, were also analyzed. · Results: Angioid streaks may be hyperfluorescent, hypofluorescent or invisible on indocyanine green angiography. Hyperfluorescent streaks were found in 88% of eyes, hypofluorescent streaks in 11%; in 18% of eyes some streaks were not visualized by indocyanine green angiography. The peau d’orange stained as a speckled pattern in the midperiphery; the flecks were concentrated temporal to the macula. Eighteen eyes presented classic and 6 occult choroidal neovascularization. In several eyes a plaque-like lesion was seen on indocyanine angiography that did not correspond to occult choroidal neovascularization on fluorescein angiography. · Conclusion: Indocyanine angiography outlines angioid streaks as well as the peau d’orange appearance better than fluorescein angiography in the majority of cases. In some cases, however, funduscopically visible streaks can not be visualized. Sometimes classic choroidal neovascular membranes are not visualized by conventional indocyanine green angiography. Occult choroidal neovascularization is better defined by indoycanine green angiography. The fluorescence of angioid streaks and of plaque-like lesions makes the interpretation of indocyanine green angiography difficult.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Documenta ophthalmologica 55 (1983), S. 91-105 
    ISSN: 1573-2622
    Keywords: choroidal neovascularization ; natural history ; prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The natural history of choroidal neovascularization is described. Whereas the evolution of the response in various conditions is more or less similar, the extent of the lesion and thus the ultimate prognosis probably depends on the etiology and perhaps also on the involvement of the choroid. The prognosis is also markedly influenced by the site of appearance of the choroidal neovascular membrane.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-2622
    Keywords: Antioxidant ; Plasma ; Senile cataract
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between overall plasma antioxidant activity and senile cataract was examined in 148 subjects aged 37–90 years. Antioxidant activity of plasma from 52 control and 96 patients with senile cataract was determined by a method which measures the capacity of plasma to inhibit auto-oxidation of bovine brain homogenate. In contrast to previous studies which demonstrated a relationship between decreased levels of antioxidant components in blood and the occurrence of lens opacities, the present study does not show any significant difference between subjects with and without senile cataract.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 16 (1992), S. 197-198 
    ISSN: 1573-2630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 18 (1994), S. 49-49 
    ISSN: 1573-2630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 1 (1979), S. 171-174 
    ISSN: 1573-2630
    Keywords: multiple optic pits ; serous detachment ; wedge-shaped choroidal dystrophy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A case of double optic pit is presented with minimal macular involvement but with an extensive wedge-shaped area of choroidal dystrophy in the nasal fundus. This wedge-shaped area of dystrophy is ophthalmoscopically and fluoroangiographically similar to the lesions of choroidal infarction. As however, it is situated near the nasal pit it might be the result of an unnoticed serous detachment related to the presence of the pit.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 1 (1979), S. 197-198 
    ISSN: 1573-2630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    International ophthalmology 2 (1980), S. 61-62 
    ISSN: 1573-2630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-2630
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract High resolution surface receiver coil nuclear magnetic resonance imaging (MRI) of the eye and paraorbital areas was performed in a patient with a malignant choroidal melanoma before and after local radiotherapy using rhutenium application. The resulting improvement in signal-to-noise ratio allows for a reduction in the imaging voxel size to 0.31 × 0.31 × 3 mm3 which provided useful morphological information with respect to delineation of tumoral mass. In the same MRI session using a standard head coil imaging method, T1 and T2 relaxation time values were calculated in regions of interest of 3 × 3 mm by means of transversal scan images of orbital and cranial tissues performed in scan times of 7 to 9 minutes. The procedure presented here combines in one single session high resolution imaging performance, previously unobservable in MRI and in other noninvasive imaging techniques, with fast and reliable measurement of T1 and T2 relaxation times within small regions of interest. MRI, a non ionizing technique, offers within reasonable acquisition times not only a good multiplanar description of the site, size and volume of normal and pathologic orbital structures, but, in addition, the prospect of soft tissue differentiation and of accurately documenting the response to and side effects of the therapy of ocular tumors.
    Type of Medium: Electronic Resource
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