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Region 4 of σ as a target for transcription regulation (2003)

Dove, Simon L. ; Darst, Seth A. ; Hochschild, Ann

Oxford, UK : Blackwell Science Ltd

Molecular microbiology 48 (2003), S. 0

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ISSN: 1365-2958

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Biology , Medicine

Notes: Bacterial σ factors play a key role in promoter recognition, making direct contact with conserved promoter elements. Most σ factors belong to the σ70 family, named for the primary σ factor in Escherichia coli. Members of the σ70 family typically share four conserved regions and, here, we focus on region 4, which is directly involved in promoter recognition and serves as a target for a variety of regulators of transcription initiation. We review recent advances in the understanding of the mechanism of action of regulators that target region 4 of σ.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1046/j.1365-2958.2003.03467.x

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