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  • 2000-2004  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 76 (2000), S. 3825-3827 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Optical excitation has been combined with the scanning tunneling microscope and a laser-induced change in the tunneling gap width of about 0.25 Å, shows a resonance effect with the electronic absorption of the sample, a monolayer of the J-aggregating dye 1,1′-diethyl-2,2′-cyanine bromide on a silver substrate. The strength of the effect is reduced by spacing the J aggregate away from the silver substrate using a carboxylic acid functionalized alkylthiol self-assembled monolayer. We propose that the origin of the resonant response is the nonradiative decay of the molecular excited state into the underlying metal substrate that causes local heating and thermal expansion. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford UK : Blackwell Science Ltd
    Journal of advanced nursing 33 (2001), S. 0 
    ISSN: 1365-2648
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A descriptive study of meaning of illness in chronic renal disease Aim. To explore the subjective meaning of illness in a sample of renal patients. Background. Patients’ illness representations, such as the meaning they attach to illness, may affect their coping and adaptation. Improved understanding in this area may therefore benefit patient care. Meaning of illness has not previously been explored in renal disease. Design and methods. Cross-sectional survey (n=405) in a single regional renal unit in the North of England. Ethical approval was obtained and patients gave written consent. The instrument used was an eight-item schema, based on the work of Lipowski (1970, Psychiatry in Medicine1, 91–102). Field notes regarding rationale for choice were recorded concurrently, then content analysed to enable identification of themes. The chi-square test (significance level P 〈 0·05) was used to analyse differences in selected meaning in older and younger patients; males and females; and patient groups (predialysis, haemodialysis and transplant). Findings. ‘Challenge’ was selected by most patients (n=253, 62·5%), with similar results in all three patient groups. Slightly more older than younger patients selected ‘challenge’, although the difference was not statistically significant and older patients more commonly had a fatalistic interpretation of the option. More men selected ‘challenge’ than women. Those selecting ‘challenge’ and ‘value’ appeared to have a more positive outlook than other patients. Conclusions. Patients had identifiable meanings for their illness, and these may be associated with their response to renal disease. The schema appeared to be comprehensive, but is in need of further refinement. Consideration of the possible influence of social desirability is necessary.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1572-994X
    Keywords: viroids ; apscaviroids ; phylogenetic analysis ; RNA quasi-species ; subviral RNAs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Field-grown citrus trees often harbor complex mixtures of 4–5 different viroid species, and the presence of citrus viroid III (CVd-III) has been shown to reduce the rate of tree growth without inducing disease. To more fully define the structure of its quasi-species, we have examined nine citrus viroid complexes for the presence of previously undescribed sequence variants of CVd-III. Analysis of 86 full-length cDNAs generated from these nine viroid complexes by RT-PCR revealed the presence of 20 new CVd-III variants. Chain lengths ranged from 293–297 nucleotides, and sequence changes were confined largely to the lower portions of the central conserved region and variable domain. The previously described variants CVd-IIIa (297 nt) and CVd-IIIb (294 nt) were clearly predominant, but phylogenetic analysis indicated that certain isolates may contain representatives of two additional fitness peaks. At least one group of CVd-III variants appears to have arisen as a result of RNA recombination. Populations recovered from diseased/declining trees were the most diverse, but even dwarfing isolates originating from old line Shamouti trees showed considerable variability.
    Type of Medium: Electronic Resource
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