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Saturation effects in Y2SiO5:Tb under low-voltage excitation (2000)

Stoffers, C. ; Lee, R. Y. ; Penczek, J. ; [et al.]

Woodbury, NY : American Institute of Physics (AIP)

Applied Physics Letters 76 (2000), S. 949-951

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ISSN: 1077-3118

Source: AIP Digital Archive

Topics: Physics

Notes: Low-voltage field emission device phosphors that are excited at high current densities often exhibit brightness saturation with increasing current. The physical processes responsible for saturation can be complex, with several mechanisms contributing, including ground state depletion and excited energy transfer. A two-level model, in conjunction with cathodoluminescence brightness and transient measurements, is used to show the influence of ground state depletion and thermal quenching on the saturation behavior of Y2SiO5:Tb under low-voltage excitation. © 2000 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.125901

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Monoaminergic Activity in Subregions of Raphé Nuclei Elicited by Prior Stress and the Neuropeptide Corticotropin-Releasing Factor (2003)

Summers, C. H. ; Kampshoff, J. L. ; Ronan, P. J. ; [et al.]

Oxford, UK : Blackwell Science Ltd

Journal of neuroendocrinology 15 (2003), S. 0

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ISSN: 1365-2826

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Corticotropin-releasing factor (CRF) coordinates neuroendocrine responses to stressful stimuli; one mechanism through which CRF may modulate hypothalamic-pituitary-adrenal axis activity is via actions on neuromodulatory systems such as serotonergic systems. Recent electrophysiological studies and the distribution of CRF receptors within midbrain and pontine raphé nuclei suggest that stress and CRF may have actions on topographically organized subpopulations of serotonergic neurones. We compared the effects of vehicle or intracerebroventricular r/hCRF injections (0, 0.1, 1 or 10 µg) in rats previously maintained in home cages or restrained for 1 h, 24 h before injection, on monoamine and monoamine metabolite tissue concentrations in the dorsal (lateral wings, rostral midline, caudal midline), median (rostral, caudal) and interfascicular raphé subdivisions of the midbrain and pontine raphé nuclei, using brain microdissection and high-performance liquid chromatography with electrochemical detection. At the lowest dose studied (0.1 µg), CRF infusions in previously stressed rats decreased 5-hydroxytryptophan (5-HTP) and 5-hydroxyindoleacetic acid (5-HIAA) concentrations only within the rostral median raphé nucleus. At higher doses, CRF infusions in previously stressed rats increased tissue concentrations of 5-HTP, serotonin (5-HT), or the serotonin metabolite, 5-HIAA, within rostral (but not caudal) regions of the median and dorsal raphé nuclei. By contrast, restraint stress alone had no effect on tissue concentrations of 5-HTP, 5-HT or 5-HIAA measured 24 h later in any subdivision, while CRF injections in rats not previously exposed to restraint stress, with few exceptions, also had no effect. These results suggest that the effects of CRF on serotonergic function are context-dependent, dose-dependent, and regionally specific within subdivisions of the brainstem raphé nuclei.