ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The kinetics of the equilibrium in aqueous solution between the diasteromers of 2-Chloro-11-(4-methyl-1-piperazinyl-4-oxide)-dibenzo-[b, f]-1,4-thiazepine-5-oxide (V) have been investigated. Both isomers differ in the position of the oxygen atom of the sulphoxide group. The sulphoxide group. The isomer with a pseudo-equatorial oxygen atom is 0.75 kcal/mol more stable than the isomer with the pseudo-axial oxygen atom. The calculated free energies of activation δG≠ are 24.6 kcal/mol and 23.9 kcal/mol.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19690520831
Permalink