Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    AT LEAST FOUR MHC CLASS I GENES ARE TRANSCRIBED IN THE HORSE: PHYLOGENETIC ANALYSIS SUGGESTS AN UNUSUAL EVOLUTIONARY HISTORY FOR THE MHC IN THIS SPECIES (1995)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of immunogenetics 22 (1995), S. 0 
    Details
    ISSN: 1744-313X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: Nineteen horse MHC class I specificities have been serologically identified previously at a single locus (ELA-A), and two other specificities appear to be coded at other loci. Biochemical studies indicate that there are at least two expressed loci. In order to establish the number of transcribed horse MHC class I genes, we made a cDNA library from a heterozygous animal (ELA-A3/A7), and screened for positive clones using a bovine class I probe. More than 200 class I clones were isolated in this way, and so far seven unique full length sequences have been identified. All of the sequences are predicted to code for surface expressed, functional molecules. The number of different sequences identified demonstrate that at least four genes are transcribed, although variations in transmembrane length (which is generally conserved in class I loci) suggest that five genes could be represented. Evolutionary analysis of these sequences (and two additional sequences known to represent different horse class I loci) reveals no firm relationships, such that the division between the different loci cannot be discerned. These results suggest an unusual evolutionary history for the horse MHC, the precise nature of which may be revealed only following further cross-species comparisons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1744-313X.1995.tb00239.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Effect of Structure on the Stereochemistry of Electrode Reactions. Monobromo C4 Dibasic Acids and Esters (1961)
    s.l. : American Chemical Society
    Analytical chemistry 33 (1961), S. 330-334 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60171a005
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    An Improvement in the Ductility of Beryllium at High Temperatures (1960)
    [s.l.] : Nature Publishing Group
    Nature 187 (1960), S. 494-496 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig 1. Vacuum cast, pebble beryllium extruded at 1,050 C. 44 : 1 reduction Fig. 2. Thermally reduced beryllium, vacuum cast and extruded at 1,050 C. 44 :1 reduction Some increase in low-temperature ductility can be obtained by fabrication techniques which develop a texture in which the basal ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/187494b0
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Congenital diaphragmatic hernia: lung compliance after antenatal tracheal obstruction or surgical correction of the defect (1996)
    Springer
    Pediatric surgery international 11 (1996), S. 524-527 
    Details
    ISSN: 1437-9813
    Keywords: Diaphragmatic hernia ; Compliance ; Plug Fetal surgery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fetal lambs with diaphragmatic herniae (CDH) created surgically at 73 days' gestation were subjected to three different forms of intrauterine correction: silastic patch correction of the diaphragmatic defect plus an abdominal patch at 101 days gestation; an intrathoracic “silo” at 101 days; and a tracheal “plug” obstruction at 101 or 129 days. At 143 days' gestation (term 145–149 days), the lambs were delivered by caesarean section and ventilated for 30 min before undergoing respiratory compliance measurements. These results were compared to those of normal lambs and animals with uncorrected herniae. The total respiratory system compliance values in those groups undergoing corrections were remarkably similar: those with any form of correction had a significant improvement (P 〈 0.05) compared to those with herniae and no correction (patch = 1.57 = ± 0.182 ml/cm H2O; silo = 1.53 ± 0.179; plug at 101 days = 1.66 ± 0.311; plug at 129 days = 2.00 ± 0,175; without correction = 0.62 ± 0.073). None, however, reached the values of those with normal lungs: 2.72 ± 0.223 (P 〈 0.05). This improvement in compliance in all corrected groups suggests that fetal tracheal obstruction is as effective as the two more invasive forms of open fetal surgery carried out in this study and, as this procedure lends itself to surgery through a small uterine incision or “minimally invasive” surgery, it may be the procedure of choice to reduce the incidence of preterm labour for those human fetuses undergoing antenatal correction of a CDH.bb
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00626057
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Food partitioning by lake-dwelling triclads and glossiphoniid leeches: field and laboratory experiments (1996)
    Springer
    Oecologia 106 (1996), S. 544-550 
    Details
    ISSN: 1432-1939
    Keywords: Triclads ; Leeches ; Lakes ; Food ; Competition
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The triclads Polycelis tenuis and Dugesia polychroa and the glossiphoniid leeches Glossiphonia complanata and Helobdella stagnalis are abundant on the stony shores of productive British lakes. All species are food limited and there is considerable overlap in the diets of these triclads and leeches. This paper investigates interactions between the two groups using field and laboratory experiments to try to identify the mechanism of their co-existence. Triclad and leech numbers were manipulated inside experimental enclosures, mathced by controls, erected on the stony shore of an eutrophic English lake. Increasing the numbers of P. tenuis and D. polychroa prior to the reproductive season in spring resulted in a significant decrease in the numbers and body size of G. complanata and H. stagnalis compared with control populations in the summer months, and vice versa. However, increases and decreases were temporary with a readjustment of numbers and body size to control levels in the autumn after reproduction had ceased. It is suggested that increasing the numbers of either group elevated the severity of both intra- and interspecific competition for food. The “condition” of prey may, in part, determine the strength of competition, and this was examined in laboratory experiments in which different densities and ratios of P. tenuis and H. stagnalis were offered either live of recently crushed Asellus aquaticus. In monospecific controls, growth rates of P. tenuis were greater when fed on crushed than live Asellus, but there was no significant difference in the growth of H. stagnalis fed either live or crushed prey. In mixed cultures of predators, P. tenuis and H. stagnalis were the superior competitors when fed on crushed and live Asellus, respectively. However, when competitive pressure was low, at low densities of predators, the presence of H. stagnalis in mixed cultures fed on live prey was beneficial to the growth of P. tenuis. These results are explained in terms of the greater ability of triclads to detect damaged prey, leaking body fluids, due to their sophisticated chemosensory system, and the ability of leeches to capture live prey due to the presence of suckers. It is concluded that co-existence of the two groups in British lakes is assisted by the partitioning of food on a live or damaged basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00329714
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Contrasting mortality in young freshwater leeches and triclads (1995)
    Springer
    Oecologia 101 (1995), S. 317-323 
    Details
    ISSN: 1432-1939
    Keywords: Leeches ; Triclads ; Lakes ; Food Mortality
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A guild of leeches and triclads coexist and are the most numerous invertebrate predators on the stony shores of productive British lakes. Populations of all species are food-limited. Mortality of recruited young is considerably higher in leech than in triclad populations, and this paper investigates reasons for this. In particular, the feeding success of young leeches and triclads in relation to prey species, prey size, prey condition (alive or crushed), spatial heterogeneity (with or without the presence of stones or gravel), and the presence or absence of other young or adults predators (leeches or triclads) of the same or different species are investigated in the laboratory. Feeding success by young leeches and triclads on crushed prey without the presence of stones was high, but declined dramatically in leeches but not triclads when stones were present. Young leeches and triclads were inept at capturing live prey, of a small or large size, with the exception of soft-bodied prey such as oligochaetes. Feeding success by young predators on live prey was not increased by the presence of other young predators of the same or different species. With only a few exceptions, the presence of adult leeches, and to a much lesser extent adult triclads, increased the feeding success, growth and survival of young leeches and triclads. It is concluded that the high mortality of young leeches, compared to triclads, in field populations is due to their inability to locate damaged food in an environment with spatial heterogeneity due to a poorly developed chemosensory system. High and low levels of juvenile morality are accompanied by high and low reproductive rates in leech and triclad populations, respectively. It is unusual for a food limited population to have a high level of recruitment, but it is speculated that the characteristically high reproductive output in parasitic leeches, from which predaceous leeches are derived or have affinities, has been retained to counterbalance high juvenile mortality rates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00328817
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Increased capacity for photosynthesis in wheat grown at elevated CO2: the relationship between electron transport and carbon metabolism (1995)
    Springer
    Planta 197 (1995), S. 482-489 
    Details
    ISSN: 1432-2048
    Keywords: Carbon assimilation ; Chlorophyll fluorescence ; Electron transport ; Elevated CO2 ; Photosynthesis ; Triticum (photosynthesis)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Spring wheat (Triticum aestivum L.) was grown under optimal nutrition for six weeks at 700 and 350 μmol·mol−1 CO2 and simultaneous measurements of photosystem-II (PSII) chlorophyll fluorescence and gas exchange were conducted on intact attached leaves. Plants grown at elevated CO2 had double the concentration of CO2 at the carboxylation site (Cc) despite a lowered stomatal (gs) and mesophyll (gm) conductance compared with ambient-grown plants. Plants grown at elevated CO2 had a higher relative quantum yield of PSII electron transport (ΦPSII) and a higher relative quantum yield of CO2 fixation (ΦCO 2). The higher ΦPSII was due to a larger proportion of open PSII centres, estimated by the coefficient of photochemical quenching of fluorescence (qp), with no change in the efficiency of light harvesting and energy transduction by open PSII centres (F′v/F′m). Analysis of the relationship between ΦPSII and ΦCO 2 conducted under various CO2 and O2 concentrations showed that the higher ΦCO 2 for a given ΦPSII in leaves developed under elevated CO2 was similar to that obtained in leaves upon a partial reduction in photorespiration. Calculation of the allocation of photosynthetic electron-transport products to CO2 and O2 showed that for leaves developed in elevated CO2, there was an increase in both total linear electron flow and electron flow to CO2 and a decrease in electron flow to O2. Plants developed under elevated CO2 showed positive acclimation manifested by a higher ΦCO 2 when measured under ambient CO2 and higher assimilation rates in A/Ci curves. Initial and total activity of ribulose-1,5-bisphosphate carboxylase-oxygenase (Rubisco EC 4.1.1.39) measured in vitro increased by 16 and 15% respectively in leaves from plants grown in elevated CO2, which was in agreement with a 15% higher in vivo carboxylation efficiency. It is concluded that growth of spring wheat at elevated CO2 enhances photosynthesis due to a change in the balance of component processes manifested as an increased capacity for carbon fixation, total electron transport and Rubisco activity, and a concomitant partial reduction of photorespiration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196670
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    A point mutation in the gene encoding the Rubisco large subunit interferes with holoenzyme assembly (1996)
    Springer
    Plant molecular biology 31 (1996), S. 399-403 
    Details
    ISSN: 1573-5028
    Keywords: assembly ; tobacco ; chloroplast ; mutation ; Rubisco
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco), a key enzyme of photosynthetic CO2 fixation, is composed of 8 large and 8 small subunits. The Rubisco-deficient Nicotiana tabacum mutant Sp25 is able to synthesize the peptides for both subunits but does not contain any active holoenzyme. The phenotype is maternally inherited and thus caused by a mutation in the chloroplast genome, which also encodes the Rubisco large subunit. A comparison of the nucleotide sequences of the large subunit gene of the Sp25 mutant with that of the wild-type tobacco revealed a single nucleotide change in the Sp25 mutant. This resulted in an amino acid substitution at Gly-322, which was replaced by serine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00021801
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Predicting patients' utilities from quality of life items: an improved scoring system for the UBQ-H (1998)
    Springer
    Quality of life research 7 (1998), S. 703-711 
    Details
    ISSN: 1573-2649
    Keywords: UBQ-H ; quality of life ; utilities ; scoring system.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Utility-based Quality of Life – Heart Questionnaire (UBQ-H) is a cardiovascular extension of the Health Measurement Questionnaire. It is a multidimensional instrument that can be scored to yield a utility estimate using the Rosser Index and a classification algorithm developed for the Health Measurement Questionnaire. The aim of this study was to employ a statistical modelling approach to devise an improved scoring system. A sample of 201 cardiovascular patients completed the UBQ-H and assessed the utility of their own health state using standard gamble and time trade-off questions in an interview. Two new scoring methods were devised by regressing the UBQ-H data against patients' self-assessed utilities. The new methods gave utility estimates that correlated with angina/dyspnoea grades, life satisfaction scores and General Health Questionnaire (GHQ) scores. In a second sample of 1,112 cardiovascular patients, the UBQ-H utilities were able to distinguish between patients who had/had not experienced an adverse event (e.g. myocardial infarction) and were responsive to changes in health over time. The new scoring methods were not particularly more sensitive to quality of life effects than the original method based on the Rosser Index. However, they produced significantly lower estimates and more accurately reflected patients' self-assessed utilities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1008857131564
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    The regulation of component processes of photosynthesis in transgenic tobacco with decreased phosphoribulokinase activity (1996)
    Springer
    Photosynthesis research 49 (1996), S. 159-167 
    Details
    ISSN: 1573-5079
    Keywords: Key words ; carbon assimilation ; electron transport ; photorespiration ; Ribulose 1,5-bisphosphate regeneration limitation ; transgenic Nicotiana tabacum L.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Tobacco plants (Nicotiana tabacum L.) transformed with an inverted cDNA encoding ribulose 5-phosphate kinase (phosphoribulokinase,PRK; EC 2.7.1.19) were employed to study the in vivo relationship between photosynthetic electron transport and the partitioning of electron transport products to major carbon metabolism sinks under conditions of elevated ATP concentrations and limited ribulose 1,5-bisphosphate (RuBP) regeneration. Simultaneous measurements of room temperature chlorophyll fluorescence and CO2 gas exchange were conducted on intact leaves. Under ambient CO2 concentrations and light intensities above those at which the plants were grown, transformants with only 5% of PRK activity showed ‘down-regulation” of PS II activity and electron transport in response to a decrease in net carbon assimilation when compared to wild-type. This was manifested as a decline in the efficiency of PS II electron transport (ΦPS II), an increase in dissipation of excess absorbed light in the antennae of PS II and a decline in: total linear electron transport (J1), electron transport dedicated to carbon assimilation (JA) and electron transport allocated to photorespiration (JL). The transformants showed no alteration in the Rubisco specificity factor measured in vitro and calculated in vivo but had a relatively smaller ratio of RuBP oxygenation to carboxylation rates (vo/vc), due to a higher CO2 concentration at the carboxylation site (Cc). The relationship between ΦPS II and ΦCO 2was similar in transformants and wild-type under photorespiratory conditions demonstrating no change in the intrinsic relationship between PS II function and carbon assimilation, however, a novel result of this study is that this similar relationship occurred at different values of quantum flux, J1, JA, JL and vo/vc in the transformant. For both wild-type and transformants, an assessment was made of the possible presence of a third major sink for electron transport products, beside RuBP oxygenation and carboxylation, the data provided no evidence for such a sink.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00117666
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...