Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    CI-1002: A Combined Acetylcholinesterase Inhibitor and Muscarinic Antagonist (1995)
    Oxford, UK : Blackwell Publishing Ltd
    CNS drug reviews 1 (1995), S. 0 
    Details
    ISSN: 1527-3458
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1527-3458.1995.tb00275.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Inhibitors of V-Type ATPases, Bafilomycin A1 and Concanamycin A, Protect Against β-Amyloid-Mediated Effects on 3-(4,5-Dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium Bromide (MTT) Reduction (1999)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 72 (1999), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The functional viability of cells can be evaluated using a number of different assay determinants. One common assay involves exposing cells to 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), which is converted intracellularly to a colored formazan precipitate and often used to assess amyloid peptide-induced cytotoxic effects. The MTT assay was employed to evaluate the role of endosomal uptake and lysbsomal acidification in amyloid peptide-treated differentiated PC12 cell cultures using selective vacuolar-type (N-type) ATPase inhibitors. The macrolides bafilomycin A1 (BAF) and concanamycin A (CON) block lysosomal acidification through selective inhibition of the V-type ATPase. Treating nerve growth factor-differentiated PC12 cells with nanomolar concentrations of BAF or CON provides complete protection against the effects of β-amyloid peptides Aβ(1-42), Aβ(1-40), and Aβ(25-35) and of amylin on MTT dye conversion. These macrolides do not inhibit peptide aggregation, act as antioxidants, or inhibit Aβ uptake by cells. Measurements of lysosomal acidification reveal that the concentrations of BAF and CON effective in reversing Aβ-mediated MTT dye conversion also reverse lysosomal pH. These results suggest that lysosomal acidification is necessary for Aβ effects on MTT dye conversion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1999.0721939.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    The Reaction of Potassium Amide in Liquid Ammonia with Chloroethenes1 (1934)
    s.l. : American Chemical Society
    Journal of the American Chemical Society 56 (1934), S. 132-134 
    Details
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ja01316a040
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Resonant vibrational excitation of furan by low energy electron impact (1996)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 105 (1996), S. 7448-7453 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Our purpose was to investigate the resonant vibrational excitation of furan (C4H4O) in its electronic ground state by electron collisions. The electron energy loss measurements have been carried out at intermediate and low impact energies for a scattering angle of 30°. The spectra show peaks or groups of peaks corresponding to the excitation of the fundamental normal modes as also of the first harmonics and combinations. The energy dependence curve for the excitation of the C–H stretching vibrational modes is also reported for the impact energy range of 3–10 eV. It exhibits a broad structureless band with a maximum centered around 6 eV, which reveals an excitation mechanism through the intermediate of a shape resonance built on the electronic ground state of the neutral molecule. A comparison with benzene is made in order to help the analysis and to assign the nature as well as the symmetry of the resonance. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.472572
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Surface charge dependence of second harmonic generation from a brass electrode (1995)
    s.l. : American Chemical Society
    Langmuir 11 (1995), S. 711-715 
    Details
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/la00003a007
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Optical Second Harmonic Generation as a Probe of Selective Dissolution of Brass (1995)
    s.l. : American Chemical Society
    Langmuir 11 (1995), S. 3457-3466 
    Details
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/la00009a031
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    HELEN HART, REMARKABLE PLANT PATHOLOGIST (1900-1971) (1996)
    Palo Alto, Calif. : Annual Reviews
    Annual Review of Phytopathology 34 (1996), S. 13-23 
    Details
    ISSN: 0066-4286
    Source: Annual Reviews Electronic Back Volume Collection 1932-2001ff
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Biology
    Notes: Helen Hart was a Professor of Plant Pathology at the University of Minnesota from 1924 until retirement in 1966. Born in Janeville, Wisconsin, she died at Grants Pass, Oregon. Her scholarly research concentrated on wheat stem rust to understand host pathogen relationships and to develop rust-resistant cultivars. She did not teach formal courses but was heavily involved in making seminars a vital part of instruction, in teaching languages needed for graduate studies, and as an informal advisor for most rust research theses. She had common sense, excellent scientific judgment, and sound instincts on personnel matters that served the department well. A talented science writer, Hart served as editor of hundreds of theses and departmental manuscripts for publication. Her writing and editing skills were used as associate editor of Phytopathology for two years and as editor-in-chief from 1944-1951. A strong advocate of The American Phytopathological Sociecty, Helen Hart served on Council for 12 years and as President in 1956. Helen Hart was a great professional scientist who had a far-reaching impact on plant pathology during the twentieth century.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1146/annurev.phyto.34.1.13
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Identification of histidine residues in Wolinella succinogenes hydrogenase that are essential for menaquinone reduction by H2 (1998)
    Oxford BSL : Blackwell Science Ltd
    Molecular microbiology 30 (1998), S. 0 
    Details
    ISSN: 1365-2958
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Notes: The cytochrome b subunit (HydC) of Wolinella succinogenes hydrogenase binds two haem B groups. This is concluded from the haem B content of the isolated hydrogenase and is confirmed by the response of its cytochrome b to redox titration. In addition, three of the four haem B ligands were identified by characterizing mutants with the corresponding histidine residues replaced by alanine or methionine. Substitution in HydC of His-25, His-67 or His-186, which are, in addition to His-200, predicted to be haem B ligands, caused the loss of quinone reactivity of the hydrogenase, while the activity of benzylviologen reduction was retained. The corresponding mutants did not grow with H2 as electron donor and either fumarate or polysulphide as terminal electron acceptor. The mutants grown with formate and fumarate did not catalyse electron transport from H2 to fumarate or to polysulphide, or quinone reduction by H2, in contrast to the wild-type strain. Cytochrome b was not reduced by H2 in the Triton X-100 extract of the mutant membranes, which contained wild-type amounts of the mutated HydC protein. Substitution in HydC of His-122, His-158 or His-187, which are predicted not to be haem B ligands, yielded mutants with wild-type properties. Substitution in HydA of His-188 or of His-305 resulted in mutants with the same properties as those lacking one of the haem B ligands of HydC. His-305 is located in the membrane-integrated C-terminal helix of HydA. His-188 of HydA is predicted to be a ligand of the distal iron–sulphur centre that may serve as the direct electron donor to the haem B groups of HydC. The results suggest that each of the three predicted haem B ligands of HydC tested (out of four) is required for electron transport from H2 to either fumarate or polysulphide, and for quinone reactivity. This also holds true for the two conserved histidine residues of HydA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2958.1998.01100.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    DUODENAL ULTRASONOGRAPHY IN THE NORMAL ADULT HORSE (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Veterinary radiology & ultrasound 36 (1995), S. 0 
    Details
    ISSN: 1740-8261
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ultrasonography was used to evaluate the duodenum of 6 clinically normal horses. Examinations were performed in horses which each, alternatively, received diets of; 1) concentrates and hay, 2) hay only, or 3) after 36 hours of starvation. The duodenum was constantly visualized just ventral to the right kidney at the 16th and 17th intercostal spaces on a line joining the olecranon and tuber sacrale. Cranial to the 16th intercostal space visibility depended on thickness of interposing liver and lung field interference. Duodenal distensions, contractions and content are described. Starved horses had fewer contractions and distensions than horses on hay, or hay and concentrate diets but the difference was not significant. Duodenal wall thickness ranged from 3–4 mm. Ultrasonographically five layers, corresponding to the mucosal surface, mucosa, submucosa, muscularis propria and serosa, could be identified. A necropsy specimen of the duodenum was evaluated histologically and Ultrasonographically in a water bath for comparison.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1740-8261.1995.tb00212.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Coincident conductive and reflective middle and lower crust in southern British Columbia (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Geophysical journal international 120 (1995), S. 0 
    Details
    ISSN: 1365-246X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Geosciences
    Notes: Processing and interpretation of magnetotelluric data, recorded as part of the LITHOPROBE Southern Cordillera transect studies, across the boundary of the Intermontane and Omineca morphogeological belts reveals: (a) high electrical conductivity in the middle and lower parts of the crust everywhere, and (b) a depth dependency of geoelectric strike. The data have been modelled using two different inversion algorithms and different methods for correcting ‘static shifts’. The two different approaches gave similar results: the depth to the top of a conductive layer decreases from 15-17 km in the west across the Intermontane Belt to 8-10 km across the transition to the Omineca Belt. The top of this conductive layer is closely coincident with a layer of increased seismic reflectivity as shown by reprocessing of collocated LITHOPROBE seismic-reflection data. The eastward shallowing is associated with an increase in heat flow such that the top of the conductive and reflective zones remains at 400-450°C. This coincidence suggests that the increased reflectivity and the high electrical conductivity observed in the middle crust may have a common cause, and that their presence is limited to where the present temperature exceeds a critical value. One explanation that meets these conditions is that both the conductivity and reflectivity are produced by a small amount of aqueous fluid porosity. We propose that fluids are trapped in the middle crust by a ductile shear zone, previously interpreted from the seismic sections as the Okanagan Valley Fault to the west of Okanagan lake. The geoelectrical strike varies from N25°W for the first 5-10 km of the crust, to N20°E for the middle/lower crust, and to N60°E for the upper mantle. This variation indicates that the exotic terrane material is concentrated in the uppermost part of the crust and that the remainder of the crust is composed of ancestral North American rocks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-246X.1995.tb05915.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...