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  • 1995-1999  (3)
  • 1940-1944
  • Cardiac transplant  (1)
  • Key words Gingival hyperplasia  (1)
  • monitoring  (1)
  • multi-layer porous media  (1)
Material
Years
  • 1995-1999  (3)
  • 1940-1944
Year
Keywords
  • 1
    ISSN: 1436-3771
    Keywords: Key words Gingival hyperplasia ; Nifedipine adverse effects ; Cardiac transplant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The prevalence and severity of gingival overgrowth in organ-transplant patients medicated with cyclosporin are greater in patients concomitantly medicated with nifedipine; however, no relationship between the gingival overgrowth and any of the nifedipine pharmacological variables has been demonstrated. The study examined the effect of five nifedipine pharmacological variables (nifedipine dosage, plasma concentration and gingival crevicular fluid concentration, M1 metabolite plasma concentration and the nifedipine:M1 ratio). The effect of the nifedipine variables on the gingival overgrowth score were examined using univariate and multivariate regression analysis. Adjustment for the effect of other risk factors was made by adding the distribution of each of the nifedipine variables in turn to a stepwise regression model containing previously identified risk factors for this condition. Despite the high levels of nifedipine sequestered in the GCF, only the plasma concentration of nifedipine was identified as a risk factor for the severity of gingival overgrowth in these patients (P = 0.01) once adjusted for other known risk factors (r 2 for the model = 55%).
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-1634
    Keywords: solute transport ; multi-layer porous media ; analytical solution ; integral transform
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Technology
    Notes: Abstract An analytical solution to the one-dimensional solute advection-dispersion equation in multi-layer porous media is derived using a generalized integral transform method. The solution was derived under conditions of steady-state flow and arbitrary initial and inlet boundary conditions. The results obtained by this solution agree well with the results obtained by numerically inverting Laplace transform-generated solutions previously published in the literature. The analytical solution presented in this paper provides more flexibility with regard to the inlet conditions. The numerical evaluation of eigenvalues and matrix exponentials required in this solution technique can be accurately and efficiently computed using the sign-count method and eigenvalue evaluation methods commonly available. The illustrative calculations presented herein have shown how an analytical solution can provide insight into contaminant distribution and breakthrough in transport through well defined layered column systems. We also note that the method described here is readily adaptable to two and three-dimensional transport problems.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Water resources management 13 (1999), S. 205-218 
    ISSN: 1573-1650
    Keywords: groundwater ; management ; monitoring ; pollution prevention ; saline intrusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: Abstract The Chalk aquifer of the English South Downs is very heavily utilised. The groundwater resources have enjoyed a formal programme of management which started in the 1950s, although a number of actions had been taken earlier in order to deal with saline intrusion and potential risk to groundwater quality from urbanisation. In the late 1950s the policy of ‘leakage/storage’ boreholes was first adopted, whereby the ‘leakage’ boreholes along the coast were pumped in winter to intercept fresh water discharge to the sea and to maximise the recharge potential inland, and inland ‘storage’ boreholes were used, as much as possible, in the summer months only. A comprehensive monitoring programme supported by aquifer modelling has enabled a gradual increase in overall abstraction to take place without increasing groundwater degradation due to saline intrusion. There have been various pollution prevention strategies over the years, and these have been effective in protecting the groundwater despite the high population density and widespread agricultural activity within the South Downs. The management of the aquifer has clearly been successful; there are many lessons from this experience that can be applied to other regions and other aquifers.
    Type of Medium: Electronic Resource
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