Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    ISSN: 1573-739X
    Keywords: Albumin ; Clinical practice guidelines ; Daily patient specific decision support ; Drug use evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Chromatographic analysis of bisphosphonates in the past has been based primarily on reversed‐phase liquid chromatography (RPLC) and ion‐exchange chromatography. Gas chromatography (GC) and recently even capillary electrophoresis have also been employed. For bioanalysis, pre‐treatment of the sample is a major part of the analysis; protein precipitation, calcium precipitation, solid‐phase extraction (SPE) and derivatization have demonstrated to play an important role in bisphosphonate assays. For some of these treatments, for example SPE and derivatization, automation may be possible. Derivatization is a prerequisite for GC analysis of bisphosphonates; a volatile derivative has to be formed. For liquid chromatography, two types of derivatization are known for bisphosphonates. First, the bisphosphonate side chain can be modified by a chemical reaction to yield a derivative with advantageous chromatographic and spectroscopic properties. Secondly, by complexation of both phosphonate groups or of phosphate after decomposition of the analyte, a coloured complex can be formed. The most sensitive bioanalytical methods are based on RPLC and fluorescence detection, if necessary after derivatization. If low detection limits are not required, for example for analysis of pharmaceutical preparations, non-specific detection methods can be applied.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 0947-5117
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Description / Table of Contents: Reduction of copper loss in potable water in domestic installations by water treatmentIn the scope of examinations for water-supply companies the effects of water treatment processes on the corrosion behaviour of materials which are used for water distribution (unalloyed steel, asbestos-cement, galvanized steel and copper) were tested by the Rhenian-Westphalian Institute of Waterchemistry and Watertechnology (IWW), Institute at the Gerhard-Mercator-University-GH Duisburg.Experimental studies have been made with copper sections and weighed ring specimens. The testing conditions were similar to those in a real domestic installation. Specimens taken at different testing times have been investigated with respect to mass loss measurements. The testing results demonstrate the possibility to estimate the concentrations on copper transported into the sewage sludge by domestic sewage. The testing conditions are described and the dominant influence of the water characteristics with respect to the water treatment processes are discussed.The experiments have shown that the central dosage of inhibitors, especially phosphate-products, is able to reduce the load of copper in domestic sewage in water systems with high concentrations of natural salts. The deacidification associated with water softening and slow-decarbonisation is qualified to reduce the load of copper in water systems with high concentrations on carbon dioxide.
    Notes: Im Rahmen von Untersuchungen für Wasserversorgungsunternehmen wurden am Rheinisch-Westfälischen Institut für Wasserchemie und Wassertechnologie (IWW), Institut an der Gerhard-Mercator-Universität GH Duisburg, Versuche zum Einfluß verschiedener Wasseraufbereitungsverfahren auf das Korrosionsverhalten der in der Wasserverteilung eingesetzten Werkstoffe (unlegierter Stahl, Asbestzement, feuerverzinkter Stahl und Kupfer) durchgeführt. Dabei wurden u.a. Massenverlustraten an Kupfer ermittelt, die eine Abschätzung der aus der Hausinstallation über das Abwasser in den Klärschlamm gelangenden Kupfermengen ermöglicht. Es wird die verwendete Versuchsmethodik beschrieben. Anhand der erhaltenen Ergebnisse wird der Einfluß der Wasserbeschaffenheit, insbesondere nach verschiedenen Verfahren der Aufbereitung diskutiert und bewertet.Als Zwischenergebnis ist festzuhalten, daß die Zugabe von Phosphaten sehr gut geeignet erscheint, die ins Abwasser gelangende Kupferfracht zu reduzieren, wenn Wässer vorliegen, die aufgrund ihres Neutralsalzgehaltes (Chlorid, Sulfat, Nitrat) örtliche Korrosion in besonderem Maße begünstigen. Die chemische Entsäuerung (i.e. Entsäuerung mit einer Base, bei der gleichzeitig eine Enthärtung und Entcarbonisierung des Wassers stattfindet) erweist sich dort als besonders vorteilhaft, wo die erhöhte Kupferfracht des Ausgangswassers im wesentlichen durch einen hohen Gehalt an Kohlenstoffdioxid bedingt ist.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...