Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 11
    facet.materialart.
    Unknown
    GENESIS OF NUMBER-FORMS. (1897)
    Urbana, etc. : Periodicals Archive Online (PAO)
    American Journal of Psychology. 8:4 (1897:July) 506 
    Details
    ISSN: 0002-9556
    Topics: Psychology
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:1016-1897-004-00-000003
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 12
    Electronic Resource
    Electronic Resource
    Insulin resistance as a programmed response to fetal undernutrition (1996)
    Springer
    Diabetologia 39 (1996), S. 1119-1122 
    Details
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400663
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 13
    Electronic Resource
    Electronic Resource
    A relationship between impaired fetal growth and reduced muscle glycolysis revealed by 31P magnetic resonance spectroscopy (1995)
    Springer
    Diabetologia 38 (1995), S. 1205-1212 
    Details
    ISSN: 1432-0428
    Keywords: Key words31P nuclear magnetic resonance spectroscopy ; skeletal muscle ; glucose metabolism ; fetal growth ; programming.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thinness at birth is associated with insulin resistance and an increased prevalence of non-insulin-dependent diabetes mellitus in adult life. As muscle is an important site of insulin resistance, and because thin babies have reduced muscle mass, thinness at birth may affect muscle structure and function and impair carbohydrate metabolism. We have therefore used 31P magnetic resonance spectroscopy to investigate the bioenergetics of gastrocnemius and flexor digitorum superficialis muscles in 16 normoglycaemic women who had a low (≤ 23 kg/m3) and 9 women who had a high (〉 23 kg/m3) ponderal index at birth. In the flexor digitorum superficialis study anaerobic metabolism was stressed with a constant heavy workload. Low ponderal index subjects fatigued more rapidly (3.3 vs 5.8 min); as phosphocreatine decreased, the accompanying drop in muscle pH was less than in the high ponderal index group. In the first minute of exercise phosphocreatine fell and adenosine diphosphate rose more rapidly (p = 0.04 and 0.03, respectively). Gastrocnemius showed a similar trend late in exercise (this exercise was more oxidative, becoming more anaerobic with increasing workload). These changes were not explained by differences in body composition, muscle mass or blood flow. The findings are consistent with a decreased lactic acid and glycolytic adenosine triphosphate production in the low ponderal index group and suggest the possibility that the mechanisms which control substrate utilisation and metabolism in adult life be programmed during prenatal life. [Diabetologia (1995) 38: 1205–1212]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422370
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 14
    Electronic Resource
    Electronic Resource
    Insulin resistance as a programmed response to fetal undernutrition (1996)
    Springer
    Diabetologia 39 (1996), S. 1119-1122 
    Details
    ISSN: 1432-0428
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00400663
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 15
    Electronic Resource
    Electronic Resource
    A common mitochondrial DNA variant is associated with insulin resistance in adult life (1998)
    Springer
    Diabetologia 41 (1998), S. 54-58 
    Details
    ISSN: 1432-0428
    Keywords: Keywords Insulin resistance ; mitochondrial DNA ; mitochondrial diabetes.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Mitochondrial DNA is maternally inherited. Mitochondrial DNA mutations could contribute to the excess of maternal over paternal inheritance of non-insulin-dependent diabetes mellitus (NIDDM). We therefore investigated the relationship between this variant, insulin resistance and other risk factors in a cohort which had been well characterised with respect to diabetes. Blood DNA was screened from 251 men born in Hertfordshire 1920–1930 in whom an earlier cohort study had shown that glucose tolerance was inversely related to birthweight. The 16 189 variant (T- 〉 C transition) in the first hypervariable region of mitochondrial DNA was detected using the polymerase chain reaction and restriction digestion. DNA analysis showed that 28 of the 251 men (11 %) had the 16 189 variant. The prevalence of the 16 189 variant increased progressively with fasting insulin concentration (p 〈 0.01). The association was independent of age and body mass index and was present after exclusion of the patients with NIDDM or impaired glucose tolerance. We found that insulin resistance in adult life was associated with the 16 189 variant. This study provides the first evidence that a frequent mitochondrial variant may contribute to the phenotype in patients with a common multifactorial disorder. [Diabetologia (1998) 41: 54–58]
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001250050866
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 16
    Electronic Resource
    Electronic Resource
    A relationship between impaired fetal growth and reduced muscle glycolysis revealed by 31P magnetic resonance spectroscopy (1995)
    Springer
    Diabetologia 38 (1995), S. 1205-1212 
    Details
    ISSN: 1432-0428
    Keywords: 31P nuclear magnetic resonance spectroscopy ; skeletal muscle ; glucose metabolism ; fetal growth ; programming
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Thinness at birth is associated with insulin resistance and an increased prevalence of non-insulin-dependent diabetes mellitus in adult life. As muscle is an important site of insulin resistance, and because thin babies have reduced muscle mass, thinness at birth may affect muscle structure and function and impair carbohydrate metabolism. We have therefore used 31P magnetic resonance spectroscopy to investigate the bioenergetics of gastrocnemius and flexor digitorum superficialis muscles in 16 normoglycaemic women who had a low (≤ 23 kg/m3) and 9 women who had a high (〉23 kg/m3) ponderal index at birth. In the flexor digitorum superficialis study anaerobic metabolism was stressed with a constant heavy workload. Low ponderal index subjects fatigued more rapidly (3.3 vs 5.8 min); as phosphocreatine decreased, the accompanying drop in muscle pH was less than in the high ponderal index group. In the first minute of exercise phosphocreatine fell and adenosine diphosphate rose more rapidly (p=0.04 and 0.03, respectively). Gastrocnemius showed a similar trend late in exercise (this exercise was more oxidative, becoming more anaerobic with increasing workload). These changes were not explained by differences in body composition, muscle mass or blood flow. The findings are consistent with a decreased lactic acid and glycolytic adenosine triphosphate production in the low ponderal index group and suggest the possibility that the mechanisms which control substrate utilisation and metabolism in adult life be programmed during prenatal life.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00422370
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 17
    Electronic Resource
    Electronic Resource
    Distress and radiological investigations of the urinary tract in children (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 684-687 
    Details
    ISSN: 1432-1076
    Keywords: Radionuclide imaging ; Radiology ; Psychology ; Emotional stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distress associated with radiological investigations may be related to the information and style of parental explanation given to the child and the parents own coping style. In a questionnaire survey we assessed distress in relation to investigations of the urinary tract using the Groningen Distress Rating Scale and the Utrecht Coping List. We found the micturating cystourethrogram (MCUG) to be significantly more distressing than radionuclide investigations. MCUG distress was adversely correlated with passive and palliative parental coping styles. Results suggested that cognitive coping styles modelled by the parents ameliorated distress on dimercaptosuccinic acid scintigraphy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957153
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 18
    Electronic Resource
    Electronic Resource
    Distress and radiological investigations of the urinary tract in children (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 684-687 
    Details
    ISSN: 1432-1076
    Keywords: Key words Radionuclide imaging ; Radiology ; Psychology ; Emotional ; stress
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distress associated with radiological investigations may be related to the information and style of parental explanation given to the child and the parents own coping style. In a questionnaire survey we assessed distress in relation to investigations of the urinary tract using the Groningen Distress Rating Scale and the Utrecht Coping List. We found the micturating cystourethrogram (MCUG) to be significantly more distressing than radionuclide investigations. MCUG distress was adversely correlated with passive and palliative parental coping styles. Results suggested that cognitive coping styles modelled by the parents ameliorated distress on dimercaptosuccinic acid scintigraphy. Conclusion The high level of MCUG associated distress and presence of traumatised children in the MCUG sample, along with the potential for parental contribution to distress reduction, suggests that both children and parents would benefit from more active preparation programmes prior to MCUG testing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957153
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 19
    Electronic Resource
    Electronic Resource
    Cell-mediated infection of cervix derived epithelial cells with primary isolates of human immunodeficiency virus (1996)
    Springer
    Archives of virology 141 (1996), S. 1177-1189 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have previously demonstrated that HIV-infected transformed T-cells or monocytes adhere to monolayers of CD4-negative epithelial cells. Adhesion is soon followed by budding of HIV from infected mononuclear cells onto the surface of epithelial cells. Epithelial cells subsequently take up virus and become productively infected. Based on these findings, we proposed that sexual transmission of HIV may involve cell-mediated infection of intact mucosal epithelia of the urogenital tract. However, it has become increasingly clear that primary cells and HIV strains isolated from patients are more appropriate models for HIV infection than established cell lines and lab strains of virus. In the studies described here, we infected cervix-derived epithelial monolayers with primary monocytes infected with patient isolates of non-syncytial inducing (NSI) macrophage-tropic strains of HIV. Under the culture conditions employed, HIV-infected primary monocytes do not remain adherent to the apical surface of the epithelium, as did HIV-infected transformed cells. Instead, following adherence, the primary cells migrate between epithelial cells. Virus is secreted from a pseudopod as HIV-infected primary monocytes pass between cells of the epithelium. Productive infection of the epithelium was detected by p24 ELISA and PCR Southern blot analysis. Infection can be blocked by sera from HIV-seropositive individuals or by certain sulfated polysaccharides. These findings support the supposition that transmission of HIV may occur via cell-mediated infection of intact epithelia. The observations also hint at the possibility that HIV-infected monocyte/macrophages in semen or cervicalvaginal secretions could cross intact epithelia by passing between epithelial cells. Blocking studies suggest that it may be possible to inhibit sexual transmission of HIV either by antibodies in genital tract secretions or by a topical formulation containing certain sulfated polysaccharides.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01718823
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 20
    Electronic Resource
    Electronic Resource
    Development of a laser-based fluorescence microscope with subnanosecond time resolution (1996)
    Springer
    Journal of fluorescence 6 (1996), S. 119-125 
    Details
    ISSN: 1573-4994
    Keywords: Subnanosecond fluorescence microscopy ; fluorescence lifetime mapping ; phthalocyanine photosensitizer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract This report describes the development of a fluorescence microscope based on a standard inverted optical microscope which incorporates a pulsed picosecond dye laser excitation source and a detector consisting of a gated image intensifier coupled to a CCD camera. Fluorescence images have been obtained using gate durations of 0.5 ns from this apparatus, representing a reduction in gate duration of an order of magnitude compared with similar instruments reported by others recently. Subnanosecond gated fluorescence images of V79-4 Chinese hamster lung fibroblasts stained with a phthalocyanine photosensitizer used in photodynamic therapy are presented. The results of these measurements are discussed in terms of the intracellular distribution of the sensitizer. Other potential applications and limitations of this technique are also outlined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00732051
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...