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  • 1995-1999  (4)
  • 1870-1879
  • Critically ill  (2)
  • Key words Hydroxypropylmethylcellulose  (2)
Source
Material
Years
  • 1995-1999  (4)
  • 1870-1879
Year
Keywords
  • 1
    Electronic Resource
    Electronic Resource
    Relations between the selenium status and the low T3 syndrome after major trauma (1996)
    Springer
    Intensive care medicine 22 (1996), S. 575-581 
    Details
    ISSN: 1432-1238
    Keywords: Low T3 syndrome ; Selenium ; Deiodination ; Glutathione peroxidase ; Balance study ; Critically ill ; Trauma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective Thyroxine (T4) is deiodinated to triiodothyronine (T3) by the hepatic type I iodothyronine deiodinase, a selenoprotein that is sensitive to selenium (Se) deficiency. After severe injury, T4 deiodination is decreased, leading to the low T3 syndrome. Injury increases free radical production, which inactivates the iodothyronine deiodinase. The aims were to study the Se status after major trauma and to investigate its relation to the low T3 syndrome. Design Preliminary prospective descriptive study. Setting Intensive care unit at a university teaching hospital. Patients and methods 11 patients aged 41±4 years (mean±SEM), with severe multiple injuries (Injury Severity Score 29±2 points). A balance study was performed from day 1 to day 7. Serum and urine samples were collected from the time of admission until day 7, then on days 10, 15, 20, 25 and 30. Nonparametric tests and Pearson's correlation coefficients were used for analysis. Results Cumulated Se losses were 0.88±0.1 μmol/24h. Serum Se was decreased from admission to day 7. T3, free T3, and the T3/T4 ratio were low until day 5, being lowest on day 2; T4 and thyroid stimulating hormone were normal. Serum Se was correlated with T3 (r=0.55,p=0.0001), and with free T3 (r=0.35). Conclusion Se status is altered after trauma, with decreased Se serum levels upon admission to the ICU but with no major Se losses. Se is probably redistributed to the tissues. The correlation between Se and T3, along with the parallel decrease in T4 deiodination, indicates that reduced deiodination might be related to the transient decrease in serum Se.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708099
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Relations between the selenium status and the low T3 syndrome after major trauma (1996)
    Springer
    Intensive care medicine 22 (1996), S. 575-581 
    Details
    ISSN: 1432-1238
    Keywords: Key words Low T3 syndrome ; Selenium ; Deiodination ; Glutathione peroxidase ; Balance study ; Critically ill ; Trauma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: Thyroxine (T4) is deiodinated to triiodothyronine (T3) by the hepatic type I iodothyronine deiodinase, a selenoprotein that is sensitive to selenium (Se) deficiency. After severe injury, T4 deiodination is decreased, leading to the low T3 syndrome. Injury increases free radical production, which inactivates the iodothyronine deiodinase. The aims were to study the Se status after major trauma and to investigate its relation to the low T3 syndrome. Design: Preliminary prospective descriptive study. Setting: Intensive care unit at a university teaching hospital. Patients and methods: 11 patients aged 41±4 years (mean±SEM), with severe multiple injuries (Injury Severity Score 29±2 points). A balance study was performed from day 1 to day 7. Serum and urine samples were collected from the time of admission until day 7, then on days 10, 15, 20, 25 and 30. Non-parametric tests and Pearson‘s correlation coefficients were used for analysis. Results: Cumulated Se losses were 0.88±0.1 μmol/24 h. Serum Se was decreased from admission to day 7. T3, free T3, and the T3/T4 ratio were low until day 5, being lowest on day 2; T4 and thyroid stimulating hormone were normal. Serum Se was correlated with T3 (r=0.55, p=0.0001), and with free T3 (r=0.35). Conclusion: Se status is altered after trauma, with decreased Se serum levels upon admission to the ICU but with no major Se losses. Se is probably redistributed to the tissues. The correlation between Se and T3, along with the parallel decrease in T4 deiodination, indicates that reduced deiodination might be related to the transient decrease in serum Se.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708099
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Characterization of hydroxypropyl- methylcellulose-stabilized emulsions (1998)
    Springer
    Colloid & polymer science 276 (1998), S. 1019-1023 
    Details
    ISSN: 1435-1536
    Keywords: Key words Hydroxypropylmethylcellulose ; emulsions ; particle size ; active laser scanning
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Emulsions stabilized with hydroxypropylmethylcellulose were characterized with respect to their particle size and their flow behavior. This part of the study focuses on the former. Active laser scanning revealed that the particle size is independent of the hydroxymethylcellulose content. The critical density of the surface film was determined to be ≤0.01 g/m2. This is the basis for the interpretation of the flow behavior, which is described in detail in part II of this contribution.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050341
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Characterization of hydroxypropylmethyl- cellulose-stabilized emulsions (1998)
    Springer
    Colloid & polymer science 276 (1998), S. 1024-1031 
    Details
    ISSN: 1435-1536
    Keywords: Key words Hydroxypropylmethylcellulose ; emulsions ; stabilization ; flow behavior ; rheometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract  Emulsions stabilized with hydroxypropylmethylcellulose were characterized with respect to their particle size and their flow behavior. This part of the study focuses on the latter. During shear experiments an increase in viscosity was detected with increasing phase volume fraction. After a critical phase volume fraction, φ, of 0.6 had been exceeded, yield stresses of between 7 and 17 Pa were exhibited. In the emulsions without yield stress the relative emulsion viscosities were examined against the relevant theories, which resulted in good agreement being found with the predictions of Krieger and Dougherty. Using the extrapolated maximum phase volume fraction, it was thus possible to calculate the thickness of the adsorbate layer as approximately 60 nm. In the dynamic measurements, a maximum was determined for the material functions. This was attributed to shear-induced restructuring processes in the emulsions. The dynamic measurements in the linear viscoelastic range showed that, in spite of increasing phase volume fraction, the critical relaxation time decreased, whereas the values of the moduli rose at small oscillation frequencies. Time-dependent measurements showed that thixotropy was detected for emulsions with a phase volume fraction of φ≥0.7. Creep tests showed that the compliance fell with increasing phase volume fraction. The zero shear modulus and the relative elastic compliance were calculated for the emulsions that exhibited yield stresses. Good agreement was found between the zero shear modulus and the values for the storage modulus determined in dynamic measurements.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003960050342
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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