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NMR visibility of 35Cl- in human erythrocytes (1995)

Riddell, Frank G. ; Zhou, Zhe

Chichester : Wiley-Blackwell

Organic Magnetic Resonance 33 (1995), S. 66-69

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ISSN: 0749-1581

Keywords: NMR ; 35C1 NMR ; Erythrocytes ; Visibility of Quadrupolar Nuclei ; Relaxation ; Chemistry ; Analytical Chemistry and Spectroscopy

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: Contrary to previous reports, Cl- is visible by 35Cl NMR inside human erythrocytes. In spectra run at 49.01 MHz the intracellular chloride has a linewidth at half-height of ca 700 Hz and shows double Lorentzian character. Mn2+ was used to relax the extracellular 35Cl- to allow the intracellular 35Cl- to be seen. The experimental protocol described should allow NMR observation of anion transport rates in human erythrocytes.

Additional Material: 6 Ill.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1002/mrc.1260330111

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