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  • 1
    ISSN: 1435-2451
    Keywords: Key words Appendectomy ; Laparoscopy ; Meta-analysis ; Randomized controlled trials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aim: To compare the effectiveness and safety of laparoscopic and conventional “open” appendectomy in the treatment of acute appendicitis. Methods: Meta-analysis of randomised controlled trials available by May 1998 that compared both techniques. Within each trial and for each outcome an effect size was calculated; the effect sizes were then pooled by a random-effects model. Results: We summarised outcome data of 2877 patients included in 28 trials. Operating time was +16 min (95% confidence interval +12–20 min) longer for laparoscopic appendectomy. Overall complication rates were comparable, but wound infections were definitely reduced after laparoscopy [rate difference –4.2%, (–2.3% to –6.1%)]. Intra-abdominal abscesses, however, occurred slightly more frequently [+0.9%, (–0.4% to +2.3%)]. Hospital stay after laparoscopic appendectomy was 15 h (8–23 h) shorter, and patients returned to full fitness or work 7 days (5–9 days) earlier. Pain intensity on day 1 was slightly less. Heterogeneity was present for some outcome measures due to methodological differences among the primary studies. Conclusion: Laparoscopic appendectomy reduces wound infections and eases postoperative recovery. Nevertheless, the various differences among the primary studies and their partly flawed methodology make it difficult to generalise from these findings.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Intensivmedizin und Notfallmedizin 34 (1997), S. 426-431 
    ISSN: 1435-1420
    Keywords: Key words Trauma ; scoring systems ; APACHE ; mortality prediction ; quality control ; Schlüsselwörter Trauma ; Scores ; APACHE ; Mortalität ; Prognose ; Qualitätskontrolle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Der APACHE II Score wird häufig als Methode zur Schweregradklassifikation und Prognosestellung bei Intensivpatienten genutzt. Der Vergleich mit der tatsächlich beobachteten Mortalität erlaubt eine Qualitätskontrolle im Sinne eines Soll-Ist-Vergleichs. Intensivpflichtige Traumapatienten zeigten in einer prospektiven Beobachtungsstudie eine höhere Mortalität als die Prognose nach APACHE II erwarten ließ. Eine Überprüfung der Prognose anhand trauma-spezifischer Score-Systeme sollte die Eignung des APACHE II Scores bei Traumapatienten prüfen. Methode: Aus einer vollständigen Erfassung aller Intensivpatienten während eines 18-Monats-Zeitraums wurden die Traumapatienten identifiziert. Eine Durchsicht der Krankenakten sowie der prospektiven Notarztprotokolle ermöglichte die Bestimmung des Injury Severity Scores (ISS), des Revised Trauma Scores (RTS) sowie des TRISS. Ergebnisse: Von 938 Intensivpatienten wurden 91 als Traumapatienten (9,4%) identifiziert. Von diesen sind 11 verstorben (12,1%). Der APACHE II Score für diese Patienten war im Mittel 10,0 Punkte, was einer Prognose von 7,1% entspricht. Die Prognosen (ROD, risk of death) der trauma-spezifischen Scores lagen durchweg höher: ISS = 26,3 Punkte (RODISS = 20%), RTS = 6,38 Punkte (RODRTS = 6 – 13%) und TRISS = 0,.78 (RODTRISS = 22%). Subgruppenanalysen zeigen, daß insbesondere bei älteren Patienten und Patienten mit einem Schädel-Hirn-Trauma die Prognosen nach APACHE deutlich unter der tatsächlichen Mortalitätsrate als auch der auf TRISS basierenden Prognose liegen. Schlußfolgerung: Der APACHE II Score unterschätzt systematisch das Mortalitätsrisiko bei intensivpflichtigen Traumapatienten. Die Prognoseaussage sollte daher nicht ohne gleichzeitige Betrachtung trauma-spezifischer Scores interpretiert werden.
    Notes: Summary Introduction: The APACHE II score is a well-known measure of illness severity and is widely used for patient classification and outcome prediction in critically ill patients. Since 1993, the surgical intensive care unit (ICU) in Cologne-Merheim uses the APACHE II score for assessment of quality of care by comparing actual versus predicted mortality. The subgroup of trauma patients was identified as showing higher mortality rates than expected from scoring. A comparison with trauma-specific score systems can prove the appropriateness of the APACHE II score in trauma patients. Methods: All trauma patients in the surgical intensive care unit within an 18 months period were identified. All patients had a routine prospective APACHE II assessment. Hospital records and pre-hospital emergency physician protocols for all trauma patients were reviewed and trauma-specific prognostic scores (ISS, RTS, TRISS) were calculated. Subgroup analyses (head injury; severity of trauma; age) were performed. Results: Among 938 patients treated in the surgical ICU, 91 trauma patients were identified; 11 of them died (12.1%). The mean APACHE II score at ICU entry for this group was 10.0, which corresponds to an estimated 7.1% risk of death (RODAPACHE). The standardized mortality ratio (SMR) is, thus, 1.70. Trauma-specific scoring systems reveal higher risk of death estimates: mean ISS = 26.3 (RODISS = 20%), mean RTS = 6.38 (RODRTS = 6 – 13%), and mean TRISS = 0.78 (RODTRISS = 22%). Subgroup analysis shows under-estimation of ROD by APACHE II in elderly patients and patients with head injuries. Conclusion: The results of APACHE II score assessment in the group of trauma patients should be interpreted carefully since the actual risk of death is under-estimated. A parallel assessment of trauma-specific scoring systems like TRISS should always accompany risk of death estimates in these type of patients.
    Type of Medium: Electronic Resource
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