ISSN:
1437-7772
Keywords:
Key words Prostate cancer
;
Systematic biopsy
;
Transrectal ultrasonography
;
Prostate-specific antigen
;
T1c cancer
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Background. Random systematic biopsy is widely utilized for the diagnosis of prostate cancer. The standard method seems to be transrectal ultrasonography (TRUS)-guided sextant transrectal biopsy. In this study, the results of a TRUS-guided transperineal technique were evaluated. Methods. Between 1993 and 1996, 102 patients were diagnosed with prostate cancer by random systematic transperineal biopsy. Eight cores (four from the ventral side and four from the rectal side) were taken from each patient while the longitudinal section was monitored by TRUS. The lengths of the whole core and the cancerous lesion were measured in each biopsy specimen. The results of systematic biopsy were examined in relation to the findings of digital rectal examination (T category), histological grade, clinical stage, and serum level of prostate-specific antigen (PSA). Results. The number of positive cores increased with the T category. The percentage of cancers in the biopsy specimens also increased according to T category. In patients without metastasis, there was a weak correlation between the level of serum PSA and the cube of the total lengths of cancerous lesions in the biopsy specimens. Nonpalpable T1 cancers had more positive cores and a greater percentage of cancer on the ventral side, while in palpable cancers, cancerous tissues were found more often and at a greater incidence on the rectal side. Conclusion. There was a correlation between the clinical stage of prostate cancer and the pathological findings of random systematic transperineal biopsy under TRUS guidance.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s101470050084
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